全文获取类型
收费全文 | 1186篇 |
免费 | 45篇 |
国内免费 | 13篇 |
专业分类
耳鼻咽喉 | 3篇 |
儿科学 | 17篇 |
妇产科学 | 12篇 |
基础医学 | 105篇 |
口腔科学 | 8篇 |
临床医学 | 74篇 |
内科学 | 318篇 |
皮肤病学 | 11篇 |
神经病学 | 32篇 |
特种医学 | 177篇 |
外科学 | 288篇 |
综合类 | 7篇 |
预防医学 | 32篇 |
眼科学 | 21篇 |
药学 | 45篇 |
中国医学 | 1篇 |
肿瘤学 | 93篇 |
出版年
2022年 | 10篇 |
2021年 | 24篇 |
2020年 | 10篇 |
2019年 | 26篇 |
2018年 | 23篇 |
2017年 | 21篇 |
2016年 | 26篇 |
2015年 | 23篇 |
2014年 | 35篇 |
2013年 | 49篇 |
2012年 | 63篇 |
2011年 | 58篇 |
2010年 | 28篇 |
2009年 | 32篇 |
2008年 | 43篇 |
2007年 | 51篇 |
2006年 | 38篇 |
2005年 | 37篇 |
2004年 | 43篇 |
2003年 | 31篇 |
2002年 | 32篇 |
2001年 | 32篇 |
2000年 | 24篇 |
1999年 | 30篇 |
1998年 | 20篇 |
1997年 | 31篇 |
1996年 | 29篇 |
1995年 | 25篇 |
1994年 | 27篇 |
1993年 | 15篇 |
1992年 | 12篇 |
1991年 | 22篇 |
1990年 | 16篇 |
1989年 | 31篇 |
1988年 | 22篇 |
1987年 | 15篇 |
1986年 | 24篇 |
1985年 | 17篇 |
1984年 | 21篇 |
1983年 | 7篇 |
1982年 | 15篇 |
1981年 | 9篇 |
1980年 | 10篇 |
1979年 | 17篇 |
1978年 | 8篇 |
1977年 | 13篇 |
1976年 | 6篇 |
1975年 | 12篇 |
1973年 | 4篇 |
1968年 | 4篇 |
排序方式: 共有1244条查询结果,搜索用时 15 毫秒
1.
Endoscopic endonasal removal of an intra-suprasellar Rathke's cleft cyst: case report and surgical considerations. 总被引:3,自引:0,他引:3
A Alfieri R Schettino A Tarfani O Bonzi G A Rossi L Monolo 《Minimally invasive neurosurgery》2002,45(1):47-51
An endoscopic endonasal approach was performed to remove an intra-suprasellar Rathke's cleft cyst. Rathke's cleft cyst are benign lesions, rarely diagnosed because they are often asymptomatic. To the best of our knowledge, at least 475 cases of Rathke's cleft cysts have been reported. They seem to arise from remnants of Rathke's pouch, an invagination of the stomodeum. A 52-year-old woman, complaining of bilateral frontal headaches, was operated on by using an endoscopic endonasal approach, for an intra-suprasellar tumor. The pre-operative diagnosis was non-functioning pituitary adenoma. Intra-operatively a creamy-coloured viscous tissue was found. After the removal of the cyst contents and of the capsule, the suprasellar structures were seen well. The chiasmatic cistern, the chiasm, the pituitary stalk and the pituitary gland were visualized with 0 and 30 degree endoscopes. The pathological findings showed a well-differentiated cuboidal epithelium. The diagnosis was Rathke's cleft cyst. No post-operative complications were observed. The endoscopic technique was particularly suitable in this case, both for the Rathke's cleft features and for an excellent outcome. The Rathke's cleft cyst was easily removed by suction and the cyst wall was entirely removed with curettes and pituitary punches. The hypophysis was distinguished from the cyst and was preserved. The surgical manoeuvres were all done under direct visual control. The absence of nasal packing and of breathing difficulties made comfortable the post-operative outcome. Thus, the endoscopic endonasal approach can be considered the favourite technique in case of either intra- and/or suprasellar Rathke's cleft cysts. 相似文献
2.
C. Shustik B. M. Jamison C. Alfieri S. Scherer R. Loertscher 《British journal of haematology》1995,91(1):167-168
Summary Allotransplantation of solid organs transfers passenger leucocytes which may give rise to a state of persistent microchimaerism. In this report we describe the case of a patient who developed a solitary plasmacytoma in a transplanted kidney more than 10 years after allografting. The diagnosis was established on the basis of the presence of a monoclonal IgG kappa peak in the serum, and light chain proteinuria, the plasmacytoid features of tumour cells including cell surface expression of IgG, kappa light chains, CD20, CD38 and CD56, the absence of lytic bone lesions and a normal bone marrow biopsy, and the disappearance of the monoclonal IgG peak after graft nephrectomy. A donor origin of the tumour was established by HLA DNA typing of tumour, tumour-free kidney tissue, and peripheral blood leucocytes, respectively. 相似文献
3.
4.
Shahriar Yazdanfar Gary S. Ledley Anthony Alfieri Clifford Strauss Morris N. Kotler 《Catheterization and cardiovascular interventions》1993,28(1):72-75
Percutaneous transluminal coronary angioplasty (PTCA) of heavily calcified rigid coronary arteries has decreased success and increased complication rates. Three cases are presented describing a new technique for the dilatation of severely calcified coronary arteries that were not dilatable by conventional angioplasty methods. This technique involves the use of a balloon dilatation catheter system parallel to a guide wire. © 1993 Wiley-Liss, Inc. 相似文献
5.
Hillmann JS; Mesgarzadeh M; Revesz G; Bonakdarpour A; Clancy M; Betz RR 《Radiology》1987,165(3):769-773
Proximal femoral focal deficiency, an uncommon congenital anomaly, necessitates early radiologic classification for surgical planning and treatment. Objective radiographic criteria, including femoral length index, acetabular depth index, acetabular angle index, and shape of the proximal femur were determined in 49 patients before cartilaginous ossification of the femoral capital epiphysis; final classification was based on follow-up radiographs or findings at arthrography or surgery. These parameters were analyzed to determine the accuracy and contributions of each in classification. Correct classification into one of three groups was possible in 86% of cases with use of three of the parameters: femoral length index, acetabular depth index, and shape of the proximal femur. The acetabular angle was found to contribute insignificantly to classification. Magnetic resonance imaging, used in only one case, depicted the nonossified cartilaginous femoral capital epiphysis, thus obviating the need for invasive diagnostic procedures and facilitating early classification. 相似文献
6.
7.
8.
To test the role of serotonin in chemotherapy-induced nausea and emesis, ten cancer patients were pretreated with the serotonin synthesis inhibitor para-chlorophenylalanine (PCPA). PCPA (2 g 8 hourly for 2 or 3 days prior to cisplatin) reduced the spontaneous urinary excretion of 5-hydroxyindoleacetic acid (5-HIAA), inhibited the increase in urinary 5-HIAA induced by cisplatin and markedly attenuated the acute period of nausea and vomiting associated with the cytotoxic drug. These results indicate that gastrointestinal serotonin mediates cisplatin-induced emesis and that the amount of serotonin released by cisplatin is a major factor in determining the severity of the acute period of emesis experienced by the patient. 相似文献
9.
L E Nicolle L Buffet N Alfieri R Tate 《Infection control and hospital epidemiology》1988,9(12):553-558
In a one-year retrospective review, 138 symptomatic infections were identified in 145 admissions to a rehabilitation unit. One hundred twenty-six (91%) infections were either urinary or skin and soft tissue infections. The daily incidence of infection increased with increasing numbers of infections for infected patients. Patient factors associated with infection included male sex, young age, spinal cord injury, admission for management of decubitus ulcers or urinary infection, history of urinary infection, urologic interventions or skin breakdown, and bladder and bowel incontinence. All patients with a history of chronic urinary infection or skin breakdown developed infection. In a logistic regression model, factors that were independently associated with risk of infection in the remaining patients included sex, incontinence, chronic neurologic disease, and prior urologic interventions. This review suggests rehabilitation patients are at high risk of acquiring nosocomial infection. The subgroup of patients with the highest risk of infection are identifiable by specific characteristics. 相似文献