全文获取类型
收费全文 | 1843篇 |
免费 | 122篇 |
国内免费 | 10篇 |
专业分类
耳鼻咽喉 | 14篇 |
儿科学 | 34篇 |
妇产科学 | 42篇 |
基础医学 | 212篇 |
口腔科学 | 22篇 |
临床医学 | 158篇 |
内科学 | 471篇 |
皮肤病学 | 89篇 |
神经病学 | 139篇 |
特种医学 | 19篇 |
外科学 | 204篇 |
综合类 | 5篇 |
一般理论 | 1篇 |
预防医学 | 105篇 |
眼科学 | 10篇 |
药学 | 140篇 |
中国医学 | 5篇 |
肿瘤学 | 305篇 |
出版年
2023年 | 12篇 |
2022年 | 26篇 |
2021年 | 54篇 |
2020年 | 25篇 |
2019年 | 58篇 |
2018年 | 82篇 |
2017年 | 44篇 |
2016年 | 34篇 |
2015年 | 47篇 |
2014年 | 61篇 |
2013年 | 82篇 |
2012年 | 132篇 |
2011年 | 120篇 |
2010年 | 77篇 |
2009年 | 71篇 |
2008年 | 87篇 |
2007年 | 77篇 |
2006年 | 82篇 |
2005年 | 85篇 |
2004年 | 103篇 |
2003年 | 85篇 |
2002年 | 69篇 |
2001年 | 48篇 |
2000年 | 51篇 |
1999年 | 48篇 |
1998年 | 16篇 |
1997年 | 10篇 |
1996年 | 13篇 |
1995年 | 9篇 |
1994年 | 10篇 |
1993年 | 10篇 |
1992年 | 25篇 |
1991年 | 29篇 |
1990年 | 25篇 |
1989年 | 22篇 |
1988年 | 14篇 |
1987年 | 14篇 |
1986年 | 5篇 |
1985年 | 14篇 |
1984年 | 8篇 |
1983年 | 6篇 |
1982年 | 5篇 |
1980年 | 7篇 |
1977年 | 8篇 |
1976年 | 5篇 |
1974年 | 13篇 |
1973年 | 11篇 |
1972年 | 10篇 |
1971年 | 5篇 |
1967年 | 4篇 |
排序方式: 共有1975条查询结果,搜索用时 31 毫秒
1.
2.
Maria Gonzalez-Cao Cristina Carrera Juan Francisco Rodriguez Moreno Pedro Rodríguez-Jiménez Mónica Antoñanzas Basa Rosa Feltes Ochoa Teresa Puertolas Eva Muñoz-Couselo José Luis Manzano Ivan Marquez-Rodas Juan Martín-Liberal Ainara Soria Pilar Lopez Criado Almudena Garcia-Castaño Aram Boada Pablo Ayala de Miguel Susana Puig Guillermo Crespo Alfonso Berrocal 《Journal of the American Academy of Dermatology》2021,84(5):1412-1415
3.
4.
5.
6.
Hybrid tumours of the salivary glands. A report of two cases involving the palate and a review of the literature 总被引:1,自引:0,他引:1
Luz María Ruíz-Godoy R Adalberto Mosqueda-Taylor Lourdes Suárez-Roa Adela Poitevin Esther Bandala-Sánchez Abelardo Meneses-García 《European archives of oto-rhino-laryngology》2003,260(6):312-315
Hybrid tumours are very rare salivary gland lesions composed of two or more different tumoural entities in a single neoplasm that arise within a definite topographical region. In most cases adenoid cystic carcinoma has been the predominant component in these lesions. In this study we describe two patients with hybrid tumours located in the palate, one in a 49-year-old woman and one in a 71-year-old man. The first case involved adenoid cystic carcinoma and mucoepidermoid carcinoma, and the patient in the second case exhibited adenoid cystic carcinoma and epithelial-myoepithelial carcinoma. Both patients were treated with surgery and radiotherapy, and there has been no evidence of recurrence after 13 and 36 months of follow-up, respectively. The recognition of the histologic component with the higher grade of malignancy in every case of hybrid tumour of the salivary glands is a necessary step to determine the biological behaviour and, consequently, to determine the proper therapeutic approach. 相似文献
7.
Chronic morphine treatment produced increases in [3H]-flunitrazepam binding in some hippocampal areas of the rat brain. The differences in binding were statistically significant in some cases. Both morphine-dependent and morphine-deprived (abstinence syndrome) animals showed an identical response in binding, which confirms a real, although small, increase in benzodiazepine binding sites in the hippocampus after morphine treatment, that is not affected by a naloxone-induced abstinence syndrome under the conditions studied. These findings support the hypothesis of a morphine-induced up-regulation of benzodiazepine binding sites in the hippocampus. A possible different response in benzodiazepine binding sites 1 and 2 could explain the different findings reported in the literature. Our data suggest that the detected increase in benzodiazepine binding would be mainly due to type 2 binding sites, since the hippocampus has a higher density of this type of benzodiazepine binding sites. 相似文献
8.
E. Pujade-Lauraine H. Lu S. Mirshahi J. Soria C. Soria A. Bernadou E. K. O. Kruithof H. R. Lijnen P. Burtin 《International journal of cancer. Journal international du cancer》1993,55(1):27-31
We studied the plasminogen activation system in tumor tissue by measuring the antigen level of the 2 plasminogen activators, tissue-type (t-PA) and urokinase-type (U-PA) and their inhibitors, plasminogen-activator inhibitors type-1 (PAI-1) and type-2 (PAI-2) in the tissue extracts of 43 human benign and malignant ovarian tumors. U-PA levels were significantly higher in malignant than in benign tumors. In addition, U-PA antigen levels were higher in the metastatic tissue of advanced disease (FIGO stage III) than in the primary localized tumor (FIGO stage I/II). Also PAI-1 concentrations tended to be higher in malignant than in benign tumors, but this difference was not statistically significant. In contrast, t-PA levels were lower in metastatic than in non-metastatic tumors, whereas PAI-2 levels were unrelated to the stage of ovarian malignancy. These results were integrated in a plasminogen-activation-dependent malignancy index (U-PA × PAI-1/t-PA). This index distinguished the different groups of benign ovarian tumors, localized and metastatic ovarian carcinomas better than U-PA levels. It could be useful as a prognostic indicator in ovarian cancer © 1993 Wiley-Liss, Inc. 相似文献
9.
P L Tazzari A Bolognesi D De Totero S Pileri R Conte J Wijdenes P Hervé M Soria F Stirpe M Gobbi 《Transplantation》1992,54(2):351-356
An immunotoxin containing the B-B10 MoAb, directed against the CD25 determinant, and the ribosome-inactivating protein saporin, inhibits 3H-TdR incorporation in phytohemagglutin, allogeneic-stimulated lymphocytes (primary and secondary mixed-lymphocyte reaction), and in an alloreactive T cell clone. A lower degree of inhibition was obtained with the B-B10 MoAb, which is known to inhibit IL-2 activity, as well as with the unconjugated compounds. These results suggest that the in vivo administration of the conjugate might be a more effective tool in the treatment of patients affected by graft-versus-host disease than B-B10 alone, by inducing an efficient killing of allogeneic-reacting T lymphocytes. 相似文献
10.
A direct in vitro tissue culture method is described for the quantitation of bovine leukemia virus, utlizing a feline S+L-- cell line. 相似文献