CT引导下射频消融术治疗肝癌患者的远期#br# 疗效及对AFP、CEA水平的影响#br#

ObjectiveTo study the long term efficacy of CT guided radiofrequency ablation in patients with primary liver cancer and its effect on patients alpha fetoprotein (AFP) and carcinoembryonic antigen (CEA) levels. MethodsA total of 100 patients with primary liver cancer treated in the Second Affiliated Hospital of Chengdu Medical College from May 2016 to October 2018 were randomly divided into a test group and a control group, each with 50 patients. The control group was treated with traditional hepatic arterial infusion chemotherapy and embolization. In the experimental group, CT guided radiofrequency ablation was used in the experimental group. The survival rates and tumor volume changes at different stages of the two groups were followed up. The AFP and CEA levels of the two groups were compared before and after treatment. ResultsThe 1 year and 2 year survival rates of patients in the test group were significantly higher than those in the control group (88％ vs. 70％) and (84％ vs. 64％), and the incidence of adverse reactions was significantly lower than that in the control group (8％ vs. 26％). The difference was statistically significant (P<005); the tumor volume of the two groups of patients gradually decreased after treatment, and the tumor volume at different stages after treatment in the experimental group was significantly smaller than the control group (P<005); the AFP after treatment in the two groups And CEA levels decreased significantly, and the levels of the two indicators in the test group were significantly lower than those in the control group (P<005). ConclusionsThe rational use of CT guided radiofrequency ablation for the treatment of primary liver cancer can significantly improve the long term treatment effect, help to optimize the level of tumor markers such as AFP and CEA, and can take advantage of minimally invasive treatment to ensure Safety of clinical treatment.     

老年ERCP术后胰腺炎患者血清hs-CRP、PCT、RDW水平变化及其与胰腺炎严重程度的关系

目的 分析老年内镜逆行胰胆管造影(ERCP)术后胰腺炎(PEP)患者血清超敏C-反应蛋白(hs-CRP)、降钙素原(PCT)、红细胞分布宽度(RDW)水平变化及其与胰腺炎严重程度的关系.方法 选择235例行ERCP的老年患者,根据ERCP术后24 h内是否出现急性胰腺炎分为非PEP组(n=126)和PEP组(n=109...     

内镜逆行胰胆管造影术治疗急性胆源性胰腺炎的临床疗效

目的 探讨急性胆源性胰腺炎患者经内镜逆行胰胆管造影术治疗的效果.方法 选取我院收治的80例急性胆源性胰腺炎患者的临床资料,病患收治时间在2013年5月至2015年5月间,将患者随机分为两组,每组各有病患40例,对照组给予药物保守治疗,观察组在对照组基础上采用内镜逆行胰胆管造影术治疗,比较两组患者的炎症因子指标变化情况与治疗结果 分析.结果 ①观察组治疗后的炎性因子指标与对照组相较有统计学意义(P<0.05).②观察组的住院时间、肠道恢复通气时间、腹痛缓解时间、血清淀粉酶恢复正常时间明显短于对照组,对比有统计学意义(P<0.05).结论 急性胆源性胰腺炎患者接受常规保守治疗后,还需经内镜逆行胰胆管造影术治疗,能够促使其临床症状得以改善,值得临床推广应用.     

华蟾素微球联合顺铂及阿霉素经肝动脉化学栓塞治疗肝癌的效果及预后

目的:探讨选用华蟾素微球联合顺铂以及阿霉素经肝动脉化学栓塞对肝癌患者进行治疗的效果及预后.方法:选取2018年10月—2019年10月本院收治的60例肝癌患者,按随机数字表分为两组,给予对照组(30例)患者顺铂联合阿霉素经肝动脉化学栓塞治疗,给予观察组(30例)患者华蟾素微球+顺铂+阿霉素经肝动脉化学栓塞治疗,观察患者...     

circ＿0005230通过靶向miR-548c-3p影响胆管癌细胞增殖和凋亡的机制

目的：探讨环状RNA(circ RNA)circ＿0005230对miR-548c-3p的靶向调控和对胆管癌细胞增殖和凋亡的作用与机制。方法：实时定量PCR(q PCR)检测胆管癌组织中circ＿0005230和miR-548c-3p表达。将人胆管癌细胞RBE分为si-NC组、si-circ＿0005230组、pc DNA-NC组、pc DNA-circ＿0005230组、miR-NC组、miR-548c-3p组、si-circ＿0005230+anti-miR-NC组、si-circ＿0005230+anti-miR-548c-3p组,分别通过Lipofectamine 2000转染si-NC、si-circ＿0005230、pc DNA-NC、pc DNA-circ＿0005230、miR-NC、miR-548c-3p mimic、si-circ＿0005230和anti-miR-NC、si-circ＿0005230和miR-548c-3p inhibitor。以CCK-8法、克隆形成实验、免疫印迹实验（Western blot）和流式细胞术分别进行细胞的增殖、克隆形成、细胞周期蛋...     

CT引导下射频消融术治疗肝癌患者的远期疗效及对AFP、CEA水平的影响

目的 研究CT引导下射频消融术治疗原发性肝癌患者的远期疗效及其对患者甲胎蛋白(AFP)和癌胚抗原(CEA)水平的影响.方法 选取2016年5月至2018年10月成都医学院第二附属医院收治的100例原发性肝癌患者,随机分为试验组和对照组,每组50例,对照组采用传统肝动脉灌注化疗栓塞术治疗,试验组采用CT引导下射频消融术治...