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目的 探讨抽吸术联合微波消融术治疗甲状腺良性实体结节的安全性和有效性。方法 选取2022年1—5月于成都医学院第二附属医院·核工业四一六医院接受超声引导下甲状腺实体结节抽吸术联合微波消融术治疗的94例(94个结节)甲状腺良性实体结节患者为研究对象。在治疗后第1个月和第3个月分别记录患者甲状腺结节体积变化、结节体积缩小率(VRR)及并发症发生情况。结果 甲状腺实体结节抽吸术毕甲状腺结节体积缩小>50%,再配合微波消融止血,术后第3个月VRR(61.24±6.85)%明显大于术后第1个月VRR(54.40±12.50)%,差异有统计学意义(P<0.05)。患者治疗期间或治疗后均未观察到严重并发症;5例(5.3%)患者出现暂时性声音改变,并在3个月内恢复。94个结节治疗后,1个(1.1%)出血,2个(2.1%)术后感染,3个(3.2%)术后积液,所有结节在短期随访时体积进一步减小。结论 超声引导下抽吸术联合微波消融术治疗甲状腺良性实体结节安全有效,并发症少,且肿块明显缩小。 相似文献
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ObjectiveTo study the long term efficacy of CT guided radiofrequency ablation in patients with primary liver cancer and its effect on patients alpha fetoprotein (AFP) and carcinoembryonic antigen (CEA) levels. MethodsA total of 100 patients with primary liver cancer treated in the Second Affiliated Hospital of Chengdu Medical College from May 2016 to October 2018 were randomly divided into a test group and a control group, each with 50 patients. The control group was treated with traditional hepatic arterial infusion chemotherapy and embolization. In the experimental group, CT guided radiofrequency ablation was used in the experimental group. The survival rates and tumor volume changes at different stages of the two groups were followed up. The AFP and CEA levels of the two groups were compared before and after treatment. ResultsThe 1 year and 2 year survival rates of patients in the test group were significantly higher than those in the control group (88% vs. 70%) and (84% vs. 64%), and the incidence of adverse reactions was significantly lower than that in the control group (8% vs. 26%). The difference was statistically significant (P<005); the tumor volume of the two groups of patients gradually decreased after treatment, and the tumor volume at different stages after treatment in the experimental group was significantly smaller than the control group (P<005); the AFP after treatment in the two groups And CEA levels decreased significantly, and the levels of the two indicators in the test group were significantly lower than those in the control group (P<005). ConclusionsThe rational use of CT guided radiofrequency ablation for the treatment of primary liver cancer can significantly improve the long term treatment effect, help to optimize the level of tumor markers such as AFP and CEA, and can take advantage of minimally invasive treatment to ensure Safety of clinical treatment. 相似文献
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目的:探讨选用华蟾素微球联合顺铂以及阿霉素经肝动脉化学栓塞对肝癌患者进行治疗的效果及预后.方法:选取2018年10月—2019年10月本院收治的60例肝癌患者,按随机数字表分为两组,给予对照组(30例)患者顺铂联合阿霉素经肝动脉化学栓塞治疗,给予观察组(30例)患者华蟾素微球+顺铂+阿霉素经肝动脉化学栓塞治疗,观察患者... 相似文献
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夏旭良 《中华普外科手术学杂志(电子版)》2020,14(1):94-96
目的探讨经口入路腔镜下甲状腺癌根治术的临床疗效及预后。
方法回顾性分析2016年1月至2017年12月150例甲状腺癌患者资料,根据术式不同分为采取开放手术治疗的传统组及采取经口入路腔镜下甲状腺癌根治术的经口组各75例。数据均采用SPSS22.0统计软件进行处理,术中术后各项指标、术后疼痛评分、生活质量评分采用(
±s)表示,独立t检验,并发症发生率采用χ2检验,P<0.05表示差异有统计学意义。
结果经口组手术时间、住院时间、术中出血量、术后引流量、术后疼痛评分、术后并发症发生率均低于传统组(P<0.05);淋巴结清扫数量大于传统组(P<0.05)。两组出院时生活质量评分差异无统计学意义(P>0.05),术后6个月、术后12个月均较出院时明显提高(P<0.05),组间比较经口组均高于传统组(P<0.05);随访1年,经口组复发率、颈部淋巴结转移率、远处转移率均低于对照组,差异有统计学意义(P<0.05)。
结论经口入路腔镜下甲状腺癌根治术治疗甲状腺癌取得的临床效果更佳,且患者预后更为理想,可作为优选治疗方案。 相似文献
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目的:探讨环状RNA(circ RNA)circ_0005230对miR-548c-3p的靶向调控和对胆管癌细胞增殖和凋亡的作用与机制。方法:实时定量PCR(q PCR)检测胆管癌组织中circ_0005230和miR-548c-3p表达。将人胆管癌细胞RBE分为si-NC组、si-circ_0005230组、pc DNA-NC组、pc DNA-circ_0005230组、miR-NC组、miR-548c-3p组、si-circ_0005230+anti-miR-NC组、si-circ_0005230+anti-miR-548c-3p组,分别通过Lipofectamine 2000转染si-NC、si-circ_0005230、pc DNA-NC、pc DNA-circ_0005230、miR-NC、miR-548c-3p mimic、si-circ_0005230和anti-miR-NC、si-circ_0005230和miR-548c-3p inhibitor。以CCK-8法、克隆形成实验、免疫印迹实验(Western blot)和流式细胞术分别进行细胞的增殖、克隆形成、细胞周期蛋... 相似文献
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目的 研究CT引导下射频消融术治疗原发性肝癌患者的远期疗效及其对患者甲胎蛋白(AFP)和癌胚抗原(CEA)水平的影响.方法 选取2016年5月至2018年10月成都医学院第二附属医院收治的100例原发性肝癌患者,随机分为试验组和对照组,每组50例,对照组采用传统肝动脉灌注化疗栓塞术治疗,试验组采用CT引导下射频消融术治... 相似文献
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