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Libman A Bouamanivong S Southavong B Sydara K Soejarto DD 《Journal of ethnopharmacology》2006,106(3):303-311
A field survey of commonly used medicinal plants in the district of Paksan, Bolikhamsai Province in the Lao People's Democratic Republic (Lao P.D.R.) indicates that 55 species of plants, belonging to 49 genera in 31 families of vascular plants, are used in day-to-day medical therapy. Lao names along with uses and preparations for remedies are given. Seven species have medicinal uses that overlap with uses reported in the literature. No medicinal uses have been previously reported for 31 of the species collected based on ethnobotanical field interviews, signifying that their uses may be unique to Laos. Nine of the 31 previously unreported species are mentioned as medicinals multiple times, indicating that further research may be warranted. 相似文献
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Soejarto DD Zhang HJ Fong HH Tan GT Ma CY Gyllenhaal C Riley MC Kadushin MR Franzblau SG Bich TQ Cuong NM Hiep NT Loc PK Xuan le T Hai NV Hung NV Chien NQ Binh le T Vu BM Ly HM Southavong B Sydara K Bouamanivong S Pezzuto JM Rose WC Dietzman GR Miller BE Thuy TV 《Journal of natural products》2006,69(3):473-481
The impact of the University of Illinois at Chicago-based Vietnam-Laos International Cooperative Biodiversity Group (ICBG) Program "Studies on Biodiversity of Vietnam and Laos", which has been in operation for the period of 1998-2005, touches on five major areas of endeavor: (a) biodiversity inventory and conservation; (b) studies on medicinal plants; (c) drug discovery and development; (d) economic development; and (e) issues on intellectual property rights and benefit sharing in natural products drug discovery and development. Highlights are presented and the significance is discussed. 相似文献
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Bethany G. Elkington Kongmany Sydara Andrew Newsome Chang Hwa Hwang David C. Lankin Charlotte Simmler José G. Napolitano Richard Ree James G. Graham Charlotte Gyllenhaal Somsanith Bouamanivong Onevilay Souliya Guido F. Pauli Scott G. Franzblau Djaja Djendoel Soejarto 《Journal of ethnopharmacology》2014
Ethnopharmacological relevance
There is widespread use of traditional herbal remedies in the Lao PDR (Laos). It is common practice to treat many diseases with local plants. This research project documented and analysed some of these traditional remedies used to treat symptoms of tuberculosis (TB).Materials and methods
This research was executed by interviewing healers about plants used traditionally to treat the symptoms of TB. Samples of some of the plants were collected, and extracts of 77 species were submitted to various in vitro assays in order to determine the amount of growth inhibition of virulent Mycobacterium tuberculosis H37Rv (Mtb), as opposed to other microbes and mammalian Vero cells.Results
Interviews took place with 58 contemporary healers in 5 different provinces about plants currently used, giving a list of 341 plants. Bioassay-guided fractionation was performed on Marsypopetalum modestum (Pierre) B. Xue and R.M.K. Saunders (Annonaceae), leading to the isolation of dipyrithione, an anti-mycobacterial compound isolated for the first time from the genus Marsypopetalum through this research.Conclusions
This research has helped to increase awareness of Laos’ rich diversity of medicinal plants and will hopefully provide incentive to preserve the undeveloped forested areas that remain, which still hold a wealth of medical information for future discoveries. 相似文献4.
Soejarto DD Fong HH Tan GT Zhang HJ Ma CY Franzblau SG Gyllenhaal C Riley MC Kadushin MR Pezzuto JM Xuan LT Hiep NT Hung NV Vu BM Loc PK Dac LX Binh LT Chien NQ Hai NV Bich TQ Cuong NM Southavong B Sydara K Bouamanivong S Ly HM Thuy TV Rose WC Dietzman GR 《Journal of ethnopharmacology》2005,100(1-2):15-22
Ethnobotany/ethnopharmacology has contributed to the discovery of many important plant-derived drugs. Field explorations to seek and document indigenous/traditional medical knowledge (IMK/TMK), and/or the biodiversity with which the IMK/TMK is attached, and its conversion into a commercialized product is known as bioprospecting or biodiversity prospecting. When performed in a large-scale operation, the effort is referred to as mass bioprospecting. Experiences from the mass bioprospecting efforts undertaken by the United States National Cancer Institute, the National Cooperative Drug Discovery Groups (NCDDG) and the International Cooperative Biodiversity Groups (ICBG) programs demonstrate that mass bioprospecting is a complex process, involving expertise from diverse areas of human endeavors, but central to it is the Memorandum of Agreement (MOA) that recognizes issues on genetic access, prior informed consent, intellectual property and the sharing of benefits that may arise as a result of the effort. Future mass bioprospecting endeavors must take heed of the lessons learned from past and present experiences in the planning for a successful mass bioprospecting venture. 相似文献
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