健胃舒颗粒分煎与合煎的临床观察及实验研究

目的：观察中药颗粒分煎与合煎是否存在疗效、药效不同差异。方法：采用自拟复方健胃舒颗粒治疗脾虚肝郁型功能性消化不良患者100例，分为分煎组与合煎组各50例，对比观察两组临床疗效及药效。结果：两组临床治愈率分别为72％和70％，总有效率均为96％，差异无显著性（P＞0．05）；并且两组在抑制大鼠胃酸、胃蛋白酶活性，调节小鼠胃功能，促进小肠推进度及镇痛药理实验中差异无显著性（P＞0．05）。结论：健胃舒颗粒分煎及合煎疗效、药效保持一致，从一个侧面为单味中药浓缩颗粒在临床辨证施治中，灵活配方及加减应用，提供科学依据。     

Clinical and Experimental Study on Separately Decocted and Mingly Decocted Jianweishu(健胃舒)Granule

Objective:Toobservethedifferenceinther apeuticeffectofChineseherbalgranuledecoctedseparatelyandmingly.Methods:OnehundredpatientsoffunctionaldyspepsiaofSpleendefi ciencyandLiverstagnancytypeweretreatedwithJianweishuGranule(JWSG,健胃颗粒剂,aself formulatedrecipebytheauthors).HalfofthepatientsreceivedJWSGdecoctedseparately,halfofthemreceivedthatdecoctedmingly.Thetherapeuticeffectsbetweenthetwogroupswerecompared.Experimentalobservationontheef fectsofdifferentlydecoctedremediesinratswasalsoco…