The Effects of Astragalus membranaceus and Tripterygium hypoglaucum on NK Activity in Systemic Lupus Erythematosus

ＴｈｅＥｆｆｅｃｔｓｏｆＡｓｔｒａｇａｌｕｓｍｅｍｂｒａｎａｃｅｕｓａｎｄＴｒｉｐｔｅｒｙｇｉｕｍｈｙｐｏｇｌａｕｃｕｍｏｎＮＫＡｃｔｉｖｉｔｙｉｎＳｙｓｔｅｍｉｃＬｕｐｕｓＥｒｙｔｈｅｍａｔｏｓｕｓＺｈａｏＸｉａｏ－ｚｈｏｎｇ（赵小忠）（Ｄｅｐａｒ...     

中西结合治疗腹部手术后早期炎性肠梗阻的临床观察

目的：探讨中西结合治疗腹部手术后早期炎性肠梗阻的临床疗效。方法选取30例腹部手术后早期炎性肠梗阻患者,给予中西结合治疗,观察记录患者临床症状消除和缓解时间、住院时间,评价治疗效果。结果患者临床症状均得到显著改善,治疗总有效率达96.7%,平均住院时间7.5 d。结论中西结合治疗腹部手术后早期炎性肠梗阻的疗效确切,值得临床推广应用。     

Pixel激光治疗面部痤疮瘢痕

目的：观察Pixel激光治疗面部痤疮瘢痕的临床效果。方法：采用以色列飞顿2940nm像素激光对54例痤疮瘢痕的患者进行治疗,共治疗3～5次,每次间隔时间2～3周。除少教对疼痛敏感的患者治疗前外涂表面麻醉,其余不用任何处理。对比治疗前后的照片并进行疗效评价。结果：共治疗54例痤疮瘢痕患者,有效率75％～100％。Pixel同时可以有效改善4种不同类型痤疮,无一例色沉和瘢痕。结论：Pixel激光治疗痤疮凹陷性瘢痕疗效满意,对增生瘢痕疗效有限。是一种适合东方人痤疮瘢痕的安全,有效的治疗方法。     

腹膜后十二指肠破裂的CT诊断

腹膜后十二指肠损伤临床上往往缺乏特征性的腹膜炎的症状和体征,早期诊断困难,漏诊和误断率高[1].本文同顾性分析本院从1997年7月至2008年6月收治的12例腹膜后十二指肠破裂,男8例,女4例;年龄20～62岁,中位年龄39岁,现报道如下.     

射频治疗面部寻常性痤疮

目的:观察射频治疗面部寻常性痤疮的疗效。方法:应用射频治疗仪治疗20例面部寻常性痤疮患者,病情Ⅱ～Ⅳ级,治疗能量20～330J,每周2次,连续治疗4周,每次治疗前观察记录临床反应并拍摄皮损照片。结果:20例患者,治疗4周后观察,总有效率80%,治疗期间未发现任何不良反应。结论:非侵入性射频治疗是一种可选择用于治疗中重度寻常性痤疮安全、有效的方法。     

强脉冲光治疗皮肤色素性疾病的临床观察

目的光子嫩肤技术是用强脉冲光改善皮肤光老化的非剥脱治疗;对皮肤色素病有较好疗效.观察强脉冲光对颜面常见色素性皮肤病的短期疗效.方法应用强脉冲光对患者面部照射,治疗波长为560nm,治疗脉宽为2.4～6ms,每个光斑2～3脉冲,能量密度24～36J/cm2.每隔3周治疗一次,5～6次为一个疗程.每次治疗前采集皮损图像.按痊愈、显效、有效及无效4级做出评价.结果受治患者综合疗效有不同程度改善.色素性疾病中,雀斑和脂溢角化病的疗效最明显,毛细血管扩张也有显著疗效.其他色素病有不同程度消退.经半年以上随访未见复发.结论强脉冲光可治疗毛细血管扩张以及多种色素性皮肤损害,改善皮肤外观.其优势为无创伤,痛苦小,不影响工作.     

看图诊断解答

1.本例患者13岁左右发病,皮损主要发生在单侧臀部,为多发结节性皮损,无明显自觉症状,诊断为浅表性脂肪瘤样痣.该病是一种少见的发生在真皮的成熟的脂肪组织性疾病,很少在出生时发现,一般多在30岁之前发病.临床上分为多发经典型和单发型,前者多见,该患者是典型的多发经典型病例.     

注射透明质酸在促进面部年轻化应用中的研究进展

有研究表明透明质酸可通过刺激真皮胶原蛋白合成、抑制皮脂腺分泌以及收缩毛孔等促进面部年轻化。透明质酸也可与肉毒毒素、富血小板血浆及二氧化碳等联合注射治疗改善面部老化。本文对透明质酸促进面部年轻化的机制、分类及相应的疗效及持久性进行综述。     

Protective effect of intense pulsed light on fibroblast injury induced by UVA Ⅰ

Objective To study the protective effects of intense pulse light (IPL) on the injury of normal human skin fibroblasts (FB) induced by ultraviolet A (UVA Ⅰ ) in vitro and to explore its possible mechanism. Methods The human skin fibroblasts were isolated and cultured, and then irradiated by UVA Ⅰ (9 J/cm2) and IPL (15 J/cm2), respectively. The proliferative ability of the cells were detected by CCK-8. Cell cycle was detected by flow cytometry, and cylin D1 and CDK2 protein expression levels were detected by Western blot. Results Different doses of UVA Ⅰ irradiation caused certain damages of cultured fibroblasts. With the increasing of of UVA Ⅰ dose, cell proliferation was decreased. Cells went to death at the exposure to 11 J/cm2 UVA Ⅰ , while the proliferative activity did not change much at 7 J/cm2 UVA Ⅰ . Cells were treated with UVA Ⅰ for other 2 days, then with IPL irradiation for other 2days, showing clear stimulating to the cell proliferation as compared with the cells that received UVA Ⅰ treatment only. Flow cytometry results showed that an increase of cell proliferating index, and cell cycle protein cyclin D1 and CDK2 expression levels were also upregulated after IPL irradiation.Conclusion UVA Ⅰ irradiation may cause cell damage as showed by cell growth index, cyclin D1 and CDK2 expression, and this injury could be protected partly by IPL treatment. The intense pulsed light may regulate the expression of cyclin proteins that may promote normal fibroblast proliferation, which could be one of the mechanisms of IPL skin rejuvenation.