排序方式: 共有12条查询结果,搜索用时 15 毫秒
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目的 探讨肝移植术后胆道并发症(biliary complication,BC)发生高危因素及Clavien 分级在BC分类中的意义.方法 逐步回归法筛选BC发生的高危因素;对BC进行Clavien分级,筛选ClavienⅢb级以上BC发生的高危因素.结果 14.4% (26/181)的肝移植患者发生BC,其中ClavienⅢb级以上BC占84.6% (22/26).BC组的回归分析表明:T管留置(P=0.0090,OR=31.177),术后1d肝动脉阻力指数(RI1d)(P=0.0094,OR<0.001),术后1周肝动脉阻力指数(RI1w)(P=0.0013,OR>999.999)的差异有统计学意义,且对该疾病的发生作用显著.ClavienⅢb 以上BC组的回归分析表明:RI1d(P=0.0065,OR<0.001)、RIlw(P=0.0022,OR>999.999)的差异有统计学意义,且对该疾病的发生作用显著.结论 Clavien分级系统对胆道并发症的分类具有重要指导意义.T管的放置增加了BC发生的风险,但并不会增加ClavienⅢb以上BC的发生.术后肝动脉血流异常的存在是BC尤其是ClavienⅢb以上BC发生的独立危险因素. 相似文献
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目的探讨膝关节半月板半脱位MRI测量方法与表现,提高对该病的认识和诊断准确性。方法回顾性分析200例膝关节症状患者的临床和影像资料,该批患者均行单膝关节MRI检查,采用统一的检查和测量方法,分析膝关节内、外侧半月板MRI表现(正常、退变、撕裂)与半月板半脱位发生率的关系。结果内侧半月板:MRI表现正常的31例,其中发生半脱位1例;MRI表现为退变的86例,发生半脱位14例;MRI表现为撕裂的52例,半脱位16例。内侧半月板不同MRI表现半脱位发生率的差别有统计学意义(χ2=7.261,P0.05)。外侧半月板:MRI表现正常的41例,其中半脱位1例;MRI表现为退变的95例,半脱位8例;MRI表现为撕裂的46例,半脱位9例。外侧半月板不同MRI表现半脱位发生率的差别有统计学意义(χ2=6.079,P0.05)。内、外侧半月板半脱位的发生率的差别有统计学意义(χ2=3.930,P0.05)。结论选择合理的测量方法,有利于膝关节半月板半脱位的诊断;膝关节内、外侧半月板撕裂后半月板半脱位的发生率增大。 相似文献
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目的:建立左股骨中段闭合折骨经皮髓内克氏针固定的标准骨折模型,观察丹参接骨胶囊对SD大鼠骨折愈合过程中局部转化生长因子β1(transforming growth factor beta 1,TGF-β1)mRNA、蛋白表达,通过RT-PCR,ELISA法进行分析转化生长因子β1的表达,探讨丹参接骨胶囊对大鼠骨折愈合的机制。方法:建立闭合性的股骨干骨折髓内固定模型,分别给与相应药物灌胃治疗,在不同时相通过RT-PCR,ELISA法进行分析TGF-β1 mRNA及蛋白表达。结果:丹参接骨胶囊能促进骨折SD大鼠TGF-β1 mRNA及蛋白的表达。结论:大鼠股骨中段闭合折骨髓内克氏针固定骨折模型稳定,可操作性强,重复性好。丹参接骨胶囊能促进骨折SD大鼠TGF-β1 mRNA及蛋白的表达。 相似文献
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膝关节半月板损伤MRI分级与半月板半脱位的相关性分析 总被引:2,自引:0,他引:2
目的:探讨膝关节半月板损伤MRI分级与半月板突出的相关性。方法:回顾性分析420例有膝关节症状病人的膝关节MRI表现,进行半月板损伤MRI分级评价及半月板突出大小的测量,统计分析膝关节半月板损伤MRI分级与半月板半脱位之间的相关性。结果:420例病人,包括内外侧共840个半月板。MRI分级0级128个,其中半脱位4个;I级258个,半脱位44个;II级149个,半脱位25个;III级305个,半脱位81个。半月板MRI分级和是否发生半月板半脱位之间存在相关性(χ2=34.074,P<0.01),I~III级的发生率高于0级,I、II级之间差别不大,III级高于I、II级。在154例脱位半月板中,内侧半月板98个,外侧半月板56个,两者之间的差别有显著统计学意义(χ2=14.026,P<0.01)。结论:膝关节半月板MRI分级与半月板半脱位密切相关。 相似文献
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BACKGROUND: Salvia miltiorrhiza bone-setting capsule is a traditional Chinese medicine for the treatment of fractures due to activating blood circulation to dissipate blood stasis, reducing swelling and pain.
OBJECTIVE: To observe the effects of Salvia miltiorrhiza bone-setting capsule on the fracture healing in a rat model of closed femoral fractures.
METHODS: Rats were randomly divided into salvia miltiorrhiza bone-setting capsule group, physiological saline group and normal group. In the salvia miltiorrhiza bone-setting capsule group and physiological saline group, rat models of closed femoral fractures were prepared, and then given physiological saline and salvia miltiorrhiza bone-setting capsule 2 pills by intragastric administration. In the normal group, rats were housed normally. At 7, 14 and 28 days after fractures, hematoxylin-eosin staining conditions, serum osteocalcin, the expression of collagen type I, and the expression of protein and mRNA callus transforming growth factor-beta 1 were observed in the salvia miltiorrhiza bone-setting capsule group and physiological saline group.
RESULTS AND CONCLUSION: (1) Hematoxylin-eosin staining demonstrated that at 7 days after fractures, no significant difference was found in pathological changes of femoral fracture in salvia miltiorrhiza bone-setting capsule group and physiological saline group. At 14 and 28 days after fractures, pathological repair was more obvious in the salvia miltiorrhiza bone-setting capsule group than in the physiological saline group. (2) At 3 and 7 days after fractures, serum osteocalcin and the expression of type I collagen were significantly increased in the salvia miltiorrhiza bone-setting capsule group and physiological saline group (P < 0.05), and the expression trend was consistent in both groups. The expression was always higher in the salvia miltiorrhiza bone-setting capsule group than in the physiological saline group, and significant differences were found at 14 and 28 days after fractures (P < 0.01). (3) Transforming growth factor beta 1 expression reached a peak at 3 days after fractures, gradually reduced, increased at 14 days (the second peak), and diminished at 28 days in the salvia miltiorrhiza bone-setting capsule group and physiological saline group. The expression trend of transforming growth factor beta 1 was consistent in the salvia miltiorrhiza bone-setting capsule group and physiological saline group. At 7, 14 and 28 days, the transforming growth factor beta 1 expression was higher in the salvia miltiorrhiza bone-setting capsule group than in the physiological saline group. (4) Results showed that salvia miltiorrhiza bone-setting capsule could promote fracture healing, and its mechanism was probably associated with serum osteocalcin, the expression of collagen type I and transforming growth factor-β1.
相似文献
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关节镜下病灶清理术配合中药口服、外洗治疗踝关节骨关节炎疗效分析 总被引:1,自引:0,他引:1
目的:探讨关节镜下病灶清理术配合中药口服、外洗治疗踝关节骨关节炎的临床疗效。方法:对40例踝关节骨关节炎病人采用关节镜下病灶清理术配合中药口服、外洗治疗,采用改良McGuire踝关节评分系统对手术前后踝关节功能状况进行评分。结果:踝关节功能评分由术前(59.5±15.4)分提高到术后(85.3±12.8)分,差异有统计学意义(t=4.862,P〈0.001)。术后疗效评定,本组优30例,良6例,可2例,差2例,优良率为90。(结论:关节镜下病灶清理术配合中药口服、外洗治疗踝关节骨关节炎疗效较好,值得在临床推广。 相似文献
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恶性外周神经鞘膜瘤的CT和MRI表现 总被引:2,自引:1,他引:1
目的回顾性分析恶性外周神经鞘膜瘤的CT和MRI表现,提高对该病的诊断准确性。方法搜集恶性外周神经鞘膜瘤病人12例,术前均进行了CT或MRI检查。结果CT表现平扫上为等、低密度混合的软组织肿块影,外形不规则,边界清楚(n=9)或模糊(n=3);增强扫描时呈不均性强化,坏死区不强化。MRI表现边界模糊,信号混杂。T1WI序列上多与肌肉等信号(n=11),内示局灶性长T1信号影;T2WI抑脂序列上以略高信号为主,边界清楚(n=2)或模糊(n=10),内示局灶性长T2信号,周围软组织浸润表现为片状高信号;增强扫描时呈不均性强化。结论恶性外周神经鞘膜瘤的CT和MRI表现具有一定的特征性。 相似文献