《灵枢·行针》针灸学术思想浅析

《灵枢·行针》是《灵枢经》的重要篇章,主要论述了由于人的体质不同,在进行针刺操作时会出现6种不同的反应,并对不同反应的原因和机理做了深刻的探讨。本文从整体审查,调和阴阳、体质各异,针感迥然、辨证施治,指导临床等方面浅析针灸学术思想,这些为指导后世针灸临床的发展奠定了基础。     

基于现代文献的灸法治疗周围牲面瘫的临床证据研究

采用循证医学的方法对灸法治疗周围性面瘫的临床研究进行评价,为临床医师提供有力证据.方法:以灸法治疗周围性面瘫在临床中常见的重要问题为出发点,全面检索相关的临床研究文献,根据循证医学的五级分类标准,从高到低对收集的文献进行分类,再采用RevMan 5.0.20统计结局指标.结果:有27篇符合本研究需要.缺少高质量A级证据;B级证据表明灸法优于腺苷钴胺片等常规西药,且不良反应少;C级证据表明灸法优于地塞米松等营养神经的西药,且不良反应少.结论:灸法治疗周围性面瘫的疗效很明显,其比西药更具有一定优势,但尚需要高质量的证据来证实.     

Investigating the effects of moxibustion on serum metabolism in healthy human body based on the <Superscript>1</Superscript>H NMR metabolomics technology

Objective

To investigate the effects of moxibustion on the serum metabolism in healthy human body based on the 1H nuclear magnetic resonance (¹H NMR) metabolomics technology, and to find the differences in metabolites, as well as to elucidate the effects of moxibustion on healthy human body from the viewpoint of global metabolism.

Methods

Sixty subjects of healthy young men from the enrolled students were randomly divided into a moxibustion group and a control group using random number table, with 30 cases in each group. Subjects in the moxibustion group accepted mild moxibustion on the right Zusanli (ST 36), once a day, 15 min for each time, and continuous treatment for 10 d; those in the control group did not receive any intervention. There were 28 cases in the moxibustion group and 23 cases in the control group after interventions. On the 1st day, 5th day and 10th day of the intervention, serum samples were collected from subjects of the two groups, and metabolic spectra were obtained by the ¹H NMR technology.

Results

Before and after the intervention, serum ¹H NMR of the moxibustion group was significantly different, while the difference was insignificant in the control group. Metabolite changes in the moxibustion group were mainly in low density lipoprotein (LDL)/very low density lipoprotein (VLDL), valine, isoleucine, leucine, lactic acid, glutamine, citric acid, polyunsaturated fatty acids, creatine, glycine, glycerol, glucose, tyrosine, histidine, formic acid, alanine, lysine, acetic acid, and glutamic acid.

Conclusion

Moxibustion can cause changes of serum metabolic patterns in healthy human by influencing the concentrations of branched-chain amino acids, polyunsaturated fatty acids, and other metabolites to strengthen body's metabolisms of amino acids and fatty acid.

     

基于1H-NMR技术探讨艾灸与针刺对血清代谢物的调节作用

目的：基于核磁共振氢谱代谢组学技术（¹H-NMR）探讨艾灸与针刺对健康青年志愿者血清代谢物调节作用的差异性,从代谢物层面揭示两者的作用特点及差异。方法：将60例健康青年男性志愿者随机分为艾灸组与针刺组,每组各30例,艾灸组采用温和灸作用于右侧足三里穴,每天1次,每次15min,连续干预10天;针刺组采用不锈钢针针刺右侧足三里穴,每天1次,每次15min,连续干预10天。两组在干预0、5、10天清晨采集受试者血清,利用¹H-NMR技术对血清代谢物进行检测。结果：干预0、5天时艾灸组与针刺组的代谢模式无显著性差异;干预10天时艾灸组与针刺组的代谢模式可显著区分;艾灸与针刺干预5天后血清中表现出差异的代谢物有Creatine和Glycine（P<0.05;P<0.01）;干预10天后血清中表现出差异的代谢物有LDL/VLDL、Valine、Isoleucine、Leucine、Lactate、Glutamine、Creatine、Glucose（P<0.01）和Glycine（P<0.05）;随着干预时间的变化,艾灸与针刺对血清代谢物的调节作用有差异。结论：艾灸与针刺右侧足三里对血清代谢物有明显的调节作用,随着干预时间的变化,两者的调节作用发生变化。     

基于Wnt/β-catenin通路探讨隔药饼灸对高脂血症兔调脂机制的影响

目的 观察隔药饼灸对高脂血症兔肝组织Wnt1、β-卷曲蛋白（β-catenin）、散乱蛋白-1(dishevelled-1,dvl-1)、固醇调节元件结合蛋白1c(sterol regulatory element-binding protein1c, SREBP1c)的mRNA表达量的影响,探讨隔药饼灸调脂的作用机制。方法 将48只新西兰兔随机分为正常组、模型组、隔药饼灸组和阿托伐他汀组,每组12只。正常组采用普通饲料喂养,其余各组采用高脂饲养法喂养8周,待造模成功后,除正常组、模型组外,隔药饼灸组选取两组穴位交替施灸（Ⅰ组穴位为巨阙、天枢、丰隆;Ⅱ组穴位为心俞、肝俞、脾俞）,阿托伐他汀组将阿托伐他汀钙片碾成粉末后拌入第一口饲料喂食,每日1次,连续8周。测定各组兔血清总胆固醇（total cholesterol, TC）、甘油三酯（glycerin trilaurate, TG）、低密度脂蛋白胆固醇（low density lipoprotein cholesterol, LDL-C）含量,RT-PCR法测定各组兔Wnt1、β-catenin、dvl-1、SREBP1c的mRNA表达...     

李希君运用灯火灸法治疗神经性皮炎经验

介绍李希君老师运用传统的灯火灸法治疗神经性皮炎的经验。李师通过灯心火对经络皮部的热刺激,以激发经气,疏通经脉,促进局部气血运行,扶正祛邪,拔腐生肌,取得了非常满意的临床疗效。并附验案2则,以证疗效。     

《灵枢·五邪》学术思想浅析

《灵枢·五邪》按照邪在肺、肝、脾(胃)、肾、心的顺序,分别论述了邪气侵袭五脏,根据五脏不同生理功能而引发的不同病证表现及针刺治疗。对该篇的学术思想从五脏五行,互藏互用和五邪证治、各有法度两方面进行了归纳和概括。     

口诀式教学方法在《针法灸法》教学中的应用——以闪火法拔罐为例

目的：探索提高高职高专针法灸法授课效率的方法，融入思政教育，提升教学效果，增强针灸推拿专业学生的岗位胜任力。方法：从学生“喜动手，惧理论”现象出发，分析问题症结，提出解决方案。结果：提出对标国家针灸技术标准和执业助理医师考试，“优化教学大纲，明确教学内容及范围，精髓内容规范化”“挖掘各项针灸技术核心要领，层层提炼，针灸技术操作流程口诀化”;辅以“加强实际操作，理论联系临床应用”的情景教学方法，提高教学效率。结论：规范化口诀式授课方法能让教师积极投身教研教改，做好学生的引导者，情景教学方法能大大提高学生的学习兴趣，提高教学质量。