The NGF Point-Injection for Treatment of the Sound-Perceiving Nerve Deafness and Tinnitus in 68 Cases

Objective： To observe the therapeutic effects of the point-injection with nerve growth factor （NGF） for the sound-perceiving nerve deafness and tinnitus. Methods： The 140 cases in this series were randomly divided into a treatment group of 68 cases treated by NGF injection at the points of Yifeng （TE 17） and Wangu （GB 12）, and a control group of 72 cases orally taking Xibiling （西比灵） and adenosine triphosphate （ATP） and intramuscular injection with VB1 and VB12. Results： The total effective rate was 78.6% in the treatment group and 31.8% in the control group, with significant difference between the two groups （P〈0.05）. Conclusion： For treating nervous deafness and tinnitus, NGF point-injection may show good therapeutic effects, but inversely proportional to the illness course, age and the extent of hypoacusis.     

神经生长因子穴位注射治疗感音神经性耳聋、耳鸣68例疗效观察

目的：观察神经生长因子穴位注射治疗神经性耳聋、耳鸣的临床疗效。方法：将140例患者随机分为2组。治疗组68例用鼠神经生长因子（恩经复）穴位（翳风、完骨）封闭治疗；对照72例给予西比灵、三磷酸腺苷口服及维生素B1、维生素B12肌肉注射治疗。结果：总有效率治疗组为78．6％，对照组为31．8％，2组比较，差异有显著性意义（P〈0．05）。结论：神经生长因子穴位注射治疗神经性耳聋、耳鸣具有较好疗效，疗效与病程、年龄、听力损失程度成反比。