中医药治疗血精症研究进展

血精症是临床上常见的男科疾病之一,严重影响男性的健康和生活质量。现代医学对血精症治疗效果并不理想,而中医药在防治本病过程中有显著的特色和优势。笔者对近年来中医药治疗血精症的病因病机、辨证分型、辨证施治、专方治疗、中成药治疗、中西医结合治疗及其他疗法等方面的研究进展进行综述。     

杨小红从肾虚膀胱热论治老年女性泌尿系感染经验介绍

杨小红教授是广州中医药大学硕士研究生导师,广州中医药大学第一附属医院主任医师,师从全国名老中医陈镜合,从事临床、教学、科研工作三十余年,在治疗泌尿系统疾病方面经验丰富,疗效显著。笔者跟师学习3年余,现将杨教授治疗老年女性泌尿系感染经验总结如下。     

肿瘤从痰从脾论治的体会

中晚期肿瘤患者多为虚实夹杂、本虚标实之重症,笔者在临床中体会到,其虚可以辨证为气血阴阳及五脏之虚,但应以调治脾虚为主,其实证可以表现为气滞、痰凝、血瘀等,但应以治痰为主,在病因病机上及诊治上,始终抓住痰与脾这两个核心。下面就此论述一下。痰、脾与肿瘤发病的关系朱丹     

CLINICAL AND DIAGNOSTIC FEATURES OF SCHISTOSOMIASIS JAPONICA A REVIEW OF 200 CASES

Schistosomiasis'' japonica is one of the most important parasitic diseases in China. Ever since its dscovery in this eountry (j) its inCidenee、and extent Of enilemiCity haVe bec0删：e inCreaSlngIy evident With imprOvement Of diagnoStiC methodS and a8 a reSUlt Of inVeStiga- 戗On8 made by VariOU8 W0rkerS. It iS Well knOWn that reglonS watered by the Yan或ze RiVer were rampant w托h this di8ea8e. The vast areas of endemlelty lnclude not only the territories im!mediately traversed by the main stream and its lnnumerable tributarie8 but also districts adjaeent to the mammoth bodies of water such as Great Lake（太湖）,Poyanghu t都防湖），and Tung七inghu（洞庭湖）． Thus Kiangsu（江袜），、Chekiang 【浙江），Anhwei（安徽），Kiangsi（江西），Hupeh（湖北）and Hunan （湖南） are the proVinees of high endemicity. Rampaney of the infeStation dOes nOt, hoWever, COnfine to reglOnS of tbe Central and lOWer YangtZe Valley aS eaSeS Of SChiStOSOmiaSiS have been reCOrded il土the central plains Of Szechuan(四J”) (2—4)and sou¨thwest parC of Chin可ihcluding Kwangsi（魔西）(5)and Yunnan（雷南）（艿。8）．     

二陈汤合桃红四物汤加减治疗痤疮63例体会

痤疮是青春期常见、多发的皮肤疾患，中医称之为“肺风粉刺”、“面粉渣”等。其主要表现为粉刺、丘疹、脓疱、结节、囊肿及瘢痕。由于本病好发于面部，易反复发作，缠绵难愈，严重影响患者的美容，部分患者可能因此而发生心理障碍，甚至有相当一部分患者会因为病情较重或处理不当形成凹陷性或增生性瘢痕，严重影响患者的生活质量。近年来，随着人们生活水平的提高，痤疮成为目前患者和医务工作者关注的疾病之一。从2006年至今笔者跟随导师运用中医药治疗了63例患者，其中在用二陈汤合桃红四物汤加减治疗痤疮之痰湿瘀滞证病例，治疗后取得满意疗效，现介绍如下。     

常染色体显性遗传视网膜色素变性致病基因Peripherin/RDS的突变筛选

目的：了解中国视网膜色素变性患者（rtinitis pigmentosa,RP)中peripherin/RDS基因的突变谱及突变率。方法：应用聚合酶链-异源双链-单链构象多态性（polymerase chain reaction heteroduplex-single strand conformation polymorphism,PCR-SSCP)及DNA序列分析技术对收集的15个常染色体显性遗传视网膜色素变性家系和55例散发视网膜色素变性病人peripherin/RDS基因的第一、二外显子进行检测。结果：15个家系及55例散发病人未检测到peripherin/RDS基因突变。结论：本研究所检测的视网膜色素变性病人与RDS基因无关。显示视网膜色素变性的遗传异质性。     

The correlation between TNF-α, IL-6 in cervical mucous during follicular development and ovulation stimulation in different protocols

Objective To investigate the correlation between TNF-α and IL-6 levels in cervical mucous during follicular development and ovulation stimulation in different protocols.Methods 36 infertile women were set up as experimental groups,divided into CC, HMG, IVF-ET group,each group consisted of 12 infertile women and 15 women with normal menstrual cycles were choiced as control group.Cervical mucous during follicular phase, luteal phase and ovulation phase were collected.TNF-α, IL-6 levels in cervical mucous were measured by radioimmunology assay (RIA).Follicular development were monitored by transvaginal ultrasonagraphy.Results (1) TNF-α levels in cervical mucous of experimental groups and control group were periodically various among the reproductive cycle.It increased during follicular phase, reached to peak during ovulation phase, and decreased during luteal phase (P＜0.05).IL-6 levels had no obvious periodical changes.(2) Compared with CC and control group, levels of TNF-α,IL-6 in HMG and IVF-ET group were significantly higher (P＜0.05).(3) Levels of TNF-α and IL-6 in cervical mucous were positively correlated with the dominant follicle diameter (r=0.261, r=0.192 respectively,P＜0.05).(4) TNF-α and IL-6 showed positive correlation in the reproductive cycle (r=0.782,P＜0.05).Conclusions (1) TNF-α level shows a cyclic change in the reproductive cycle and peaks during ovulation,whereas IL-6 level does not.(2) TNF-α and IL-6 may play a certain role in the process of follicular development and ovulation.(3)The levels of TNF-α and IL-6 are up-regulated by gonadotrophic hormone.(4) TNF-α and IL-6 may have coordination properties and participate in the same biological effects.     

Comparison of clinical outcomes of frozen-thawed blastocysts transfer in natural and hormonally controlled cycles

Objectives:To assess the clinical outcomes of frozen-thawed blastocysts transfer in natural and hormonally controlled cycles.Methods:A retrospective analysis of natural and hormonally controlled cycle for 246 frozen-thawed blastocyst transfer cycles,the clinical pregnancy rate,implantation rate,early abortion rate were compared.Results:Of the 192 hormonally controlled cycles,the cancel rate,clinical pregnancy rate per ET,implantation rate and abortion rate were 7.3%(14/192),53.9%(96/178),38.8%(131/338)and 11.5%(11/96)respectively,whereas in 54 natural cycles,these rates were 16.7%(9/54),68.9%(31/45),52.9%(45/85)and 16.1%(5/31)respectively.There was no significant difference between the two groups with regard to the clinical pregnancy and abortion rate per ET,but the cancel rate and implantation rate were higher in natural cycles.However,the pregnancy and implantation rates of patients without PCOS in hormonal control cycles(57.2%,40.9%)were similar with those in natural cycles(P>0.05).Conclusion:These findings suggested that both hormonally controlled and natural cycles had similar pregnancy outcomes in frozen-thawed blastocysts transfer.