脑梗通对急性脑梗死患者外周血一氧化氮及白细胞粘附分子CD11b表达的影响

目的观察急性脑梗死患者外周血一氧化氮(NO)和白细胞粘附分子CD11b的表达变化及中药脑梗通对其影响.方法60例急性脑梗死患者随机分为脑梗通治疗组和脑血康对照组,每组各30例.采用流式细胞术测定患者治疗前后CD11b的表达,荧光分光光度法测定NO的表达.结果脑梗通组基本痊愈率和总有效率分别为43.33%和83.33%,脑血康组为33.3%和80.0%,2组间差异不显著(P＞0.05).急性脑梗死患者NO、CD11b表达比正常组显著增加(P＜0.01,P＜0.05),脑梗通治疗后,NO、CD11b表达与治疗前相比显著下降(P＜0.05),脑血康组治疗前后无显著性改变(P＞0.05).结论脑梗通治疗急性脑梗死具有较好疗效,且能有效抑制NO、CD11b的表达.     

老年脑血管病患者血浆血小板α-颗粒膜蛋白含量的变化

老年脑血管病患者血浆血小板α颗粒膜蛋白含量的变化黄柳华李求兵赵东张树益马明陈刚一、临床资料１９９３年６月至１９９５年６月住院的脑血管病患者１３７例，其中脑梗塞１１１例，脑出血２６例。脑梗塞组男７６例，女３５例；其中老年前期３５例，年龄４５～５９岁，...     

中药治疗老年睡眠障碍63例临床观察

目的:研究中药治疗老年睡眠障碍的临床疗效.方法:老年睡眠障碍患者121例随机分为中医治疗组(63例)和对照组(58例),分别采用中医辨证论治与西药舒乐安定治疗,并观察睡眠障碍量表(SDRS)、Hamilton抑郁量表(HAMA)等指标治疗前后及不同时期的变化,以判断两组的临床疗效.结果:中药对入睡困难的疗效明显,并能改善睡眠质量,其有效率为76.3%,总体疗效高于舒乐安定组(有效率69.1%).嗜睡、口干等不良反应及反跳性失眠均明显少于舒乐安定.结论:中医药治疗老年睡眠障碍有良好的临床疗效,且疗效优于舒乐安定.     

脑梗通对急性脑梗死患者外周血一氧化氮及白细胞粘附分子CD11b表达的影响

目的:观察急性脑梗死患者外周血一氧化氮(NO)和白细胞粘附分子CD11b的表达变化及中药脑梗通对其影响.方法:60例急性脑梗死患者随机分为脑梗通治疗组和脑血康对照组,每组各30例.采用流式细胞术测定患者治疗前后CD11b的表达,荧光分光光度法测定NO的表达.结果:脑梗通组基本痊愈率和总有效率分别为43.33%和83.33%,脑血康组为33.3%和80.0%,2组间差异不显著(P＞0.05).急性脑梗死患者NO、CD11b表达比正常组显著增加(P＜0.01,P＜0.05),脑梗通治疗后,NO、CD11b表达与治疗前相比显著下降(P＜0.05),脑血康组治疗前后无显著性改变(P＞0.05).结论:脑梗通治疗急性脑梗死具有较好疗效,且能有效抑制NO、CD11b的表达.     

TCM Treatment for 63 Cases of Senile Dyssomnia

In order to study the therapeutic effects of the TCM drugs on senile dyssomnia, 121 such patients were randomly divided into a treatment group of 63 cases (given the TCM drugs) and a control group of 58 cases (given estazolam). The changes shown in the SDRS and HAMA scores and the other indexes were observed in both of the two groups to evaluate the therapeutic effects. The results showed that the effective rate was 76.3% in the treatment group, and it was 69.1% in the control group; and that the TCM drugs had better effects in improving such symptoms as lethargy, dry mouth, and rebound of insomnia. Therefore, it can be concluded that the effect of the TCM drugs is better for senile dyssomnia than that of the Western drug estazolam.