针刺配合耳背割治治疗血瘀型银屑病:随机对照研究

目的:验证针刺配合耳背割治对血瘀型银屑病的临床疗效。方法:将56例血瘀型银屑病患者随机分为针割组、割治组、针刺组和对照组,每组14例。4组均在口服中药汤剂常规治疗基础上,针割组予针刺+耳背割治;割治组予模拟针刺+耳背割治;针刺组予针刺+模拟耳背割治;对照组予模拟针刺+模拟耳背割治。针刺取大椎、肺俞、肝俞、膈俞等穴,行常规操作;模拟针刺仅刺入真皮层,使毫针倾倒,但不脱落;耳背割治:取患者一侧耳背心用针进行割治放血;模拟耳背割治:取患者一侧耳背心约偏离0.5cm处为模拟割治部位。均每日1次,7次为一疗程,共进行2个疗程。观察患者治疗前后银屑病皮损面积和严重程度指数(PASI)评分,并比较各组疗效。结果:针割组有效率[57.1%(8/14)]高于割治组[14.3%(2/14)]、针刺组[7.1%(1/14)]和对照组[0.0%(0/14),均P0.05]。各组患者PASI评分治疗后均降低(均P0.05),针割组优于其他3组(均P0.05)。经析因分析,耳背割治的主效应,P0.05;针刺的主效应,P0.05;针刺和耳背割治的交互效应,P0.05。结论:针刺疗法、耳背割治配合口服中药汤剂均可降低血瘀型银屑病的PASI评分,具有明显疗效,且耳背割治、针刺疗法交互作用配合口服中药汤剂疗效最为显著。     

针刺对腰椎后路减压融合内固定术大鼠的抑炎镇痛作用及Akt/NF-κB通路的影响

目的：探讨针刺对腰椎后路减压融合内固定术大鼠的抑炎镇痛作用及蛋白激酶B(Akt)/核因子κB(NF-κB)通路的影响。方法：50只大鼠随机取10只大鼠作为对照组,剩余40只大鼠建立腰椎间盘突出症模型并进行后路减压融合内固定术。将造模成功的36只大鼠随机分为模型组、针刺组和氟比洛芬酯组,每组12只。针刺组大鼠针刺“肾俞穴”,每次20 min,1次/d,连续5 d;氟比洛芬酯组大鼠尾静脉注射氟比洛芬酯注射液,25 mg/kg,2次/d,连续5 d。热板致痛实验测定各组大鼠痛阈值,ELISA法检测血清肿瘤坏死因子-α(TNF-α)、白介素-6(IL-6)和IL-1β水平及β-内啡肽(β-EP)、P物质(SP)和五羟色胺(5-HT)含量,HE染色检测L5神经根组织病理学变化,蛋白印迹法检测背根神经节中Akt、p-Akt、NF-κB和p-NF-κB p65蛋白相对表达量。结果：对照组大鼠神经细胞结构完整、形态正常、排列整齐,未见炎症细胞浸润;模型组大鼠神经细胞排列紊乱、细胞边界模糊,明显水肿,髓鞘发生崩解,排列不整齐,有大量炎症细胞浸润;针刺组和氟比洛芬酯组大鼠神经细胞排列稍整齐,炎症细胞浸润减...     

针药结合对湿热型腹部术后胃肠功能恢复的影响

目的:观察针药结合对湿热型腹部术后患者胃肠功能恢复的影响.方法:将65例湿热型腹部术后患者随机分到中药组和针药结合组,中药组34例,针药结合组31例.两组均给予常规治疗,中药组加用院内协定方口服,针药组在中药组治疗的基础上采用针刺治疗,日1次,7d为1个疗程,7d后对胃肠功能恢复及外周白细胞数予以评价.结果:两组在术后肠鸣音恢复时间、首次肛门排气时间、首次排便时间等方面比较,差异有统计学意义(P＜0.05).两组术前、术后第1天、术后第5天的外周白细胞数、中性粒细胞数、单核细胞数比较差异无统计学意义(P＞0.05),两组术前、术后第1天淋巴细胞数比较差异也无统计学意义(P＞0.05).但针药结合组术后第5天淋巴细胞数较中药组有明显增多,组间比较差异有统计学意义(P=0.05).结论:针药结合治疗相对于单用中药治疗对改善湿热型腹部术后患者的胃肠道功能有一定效果,并对外周白细胞有良性双向调节作用.     

Observation on clinical effects of acupuncture plus external medicine application for cervical radiculopathy

Objective

To observe the clinical effects of acupuncture plus external medicine application for cervical radiculopathy.

Methods

A total of 98 patients with cervical radiculopathy were randomly divided into an observation group and a control group based on the random digital table. The observation group (50 cases) was treated by acupuncture plus external medicine application and the control group (48 cases) was treated by acupuncture alone. The patients received the treatment every day. Ten sessions made a course. Cervical spondylosis symptom scale was used to assess the cases before and after the treatment. The clinical efficacy was compared between the two groups after the treatment.

Results

The total effective rate was 98.1% in the observation group versus 87.6% in the control group with a statistically significant difference between the two groups (P<0.05). The cure rate was 52.0% in the observation group versus 18.8% in the control group with a significant difference between the two groups (P<0.05). There was no significant difference in the score of cervical spondylosis symptom scale between the two groups before the treatment (P>0.05). It increased with a significant difference in both groups after the treatment (both P<0.05), while a significant difference was found in the results between the two groups after the treatment (P<0.05).

Conclusion

Acupuncture plus external medicine application is more effective than acupuncture alone for treating cervical radiculopathy. The method also effectively improves the clinical symptoms.