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Xiao-liCHI Wen-xiaZHOU Jun-pingCHENG Yong-xiangZHANG Ke-liangLIU 《Acta pharmacologica Sinica》2004,25(11):1536
AIM: To investigate the pharmacological effect of LXT-101 on serum testosterone level in intact male rats. METHODS: Ratswere injected subcutaneously with LXT-101 while control animals received only vehicle (5% mannitol). Blood samples were collected at different times after administration of LXT- 101. The serum testosterone was determined by specific immunochemi-luminescence assay using kits produced by Beckman-Counter 相似文献
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ShengYANG Hai-faQIAO LeiWEN Wen-xiaZHOU Yong-xiangZHANG 《Acta pharmacologica Sinica》2004,25(11):1557-1558
The molecular and cellular mechanisms underlying the cognitive deficient of senescence-accelerated mouse prone/8 (SAMP8) have been attributed to many pathobiological changes in neurons. Recently, increasing evidence have shown that astrocyte, by mean of D-serine, was involved in the process of synaptic transmission. Here we reported the decrease of longterm potentiation (LTP) in SAMP8 along with aging, and the 相似文献
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Zhi-yongXIAO Wen-xiaZHOU Yong-xiangZHANG Jun-fengHE Liu-hongYUN 《Acta pharmacologica Sinica》2004,25(11):1563
Linomide, a quinoline-3-carboxamide, has a pleiotropic immune modulating capacity and inhibits development as well asprogression of disease in animal models of autoimmunity. Its benefical effects on experimental autoimmune disease models have been linked to regulation of Th 1/Th2 balance and alter macrophage functions. We studied the effect of linomide on chronic graft-versus-host disease model mice. The oral administration of 相似文献
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