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1.
Khawaja Afzal Ammar MD Saquib Samee MD Robert Colligan PhD Robert Morse MD Osman Faheem MD Molly Shapiro 《Journal of addictive diseases》2013,32(3):243-249
ABSTRACT This article aims at identifying a threshold number of drinks per day beyond which there is a high risk of developing alcoholic behavior that would enable physicians to more confidently support the use of alcohol for cardiovascular risk prevention. In a randomly selected, population-based sample of 2,042 adults 45 years or older, we graded alcohol drinking behavior using the Self-Administered Alcoholism Screening Test, quantified alcohol amount by questionnaire, and assessed the prevalence of cardiovascular disease (coronary, peripheral, or cerebrovascular disease) by medical record review. Although optimal alcohol use (≤2 drinks/day) was associated with reduced odds of cardiovascular disease, 43% of alcoholics and 82% of problem drinkers reported alcohol use in the optimal range as well. The association of alcohol use in the optimal range with alcohol-related behavioral problems supports the reluctance in physicians from recommending alcohol use for cardiovascular benefit, not withstanding the underreporting of alcohol use by alcoholics. 相似文献
2.
Chuansumrit A Mahasandana C Chinthammitr Y Pongtanakul B Laossombat V Nawarawong W Lektakul Y Wangruangsatid S Sriboriboonsin L Rojnakarin P Angchaisuksiri P;Hemophilia Study Group 《The Southeast Asian journal of tropical medicine and public health》2004,35(2):445-449
A national survey of patients with hemophilia and other congenital bleeding disorders in Thailand was conducted in the years 2000 to 2002. Questionnaires were sent to physicians working at hospitals throughout the country. Although the overall response rate to the questionnaires was 19%, the two highest rates of 80% and 73.7% were found at university and regional hospitals, respectively, where most of the patients received their diagnosis and treatment. A total of 1,450 patients comprised of hemophilia 1,325 cases, von Willebrand disease, 69 cases, congenital factor VII deficiency, 15 cases, hereditary platelet dysfunction, 22 cases, and undefined causes of congenital bleeding disorders, 19 cases. Most were pediatric patients <15 years of age. Treatment was mainly given on demand for a bleeding episode, while only 8.6% received additional home treatment for early bleeding episodes. Replacement therapy primarily relied on fresh frozen plasma, cryoprecipitate and cryo-removed plasma. Factor concentrate was seldom used because of the high price. As a result, hemophilia care services in Thailand should be strengthened by providing comprehensive education for medical personnel, making available simple laboratory kits to determine hemophilia A and B, ensuring an adequate supply of blood components and affordable factor concentrate, and establishing home care treatment. 相似文献
3.
Thientunyakit Tanyaluck Sethanandha Chakmeedaj Muangpaisan Weerasak Chawalparit Orasa Arunrungvichian Kuntarat Siriprapa Tossaporn Vichianin Yudthaphon Kamal Swatabdi Suppasilp Chaiyawat Thongpraparn Thonnapong Chanachai Rujaporn Gelovani Juri G. 《Annals of nuclear medicine》2020,34(5):337-348
Annals of Nuclear Medicine - The current study was conducted to improve the understanding of relationships between regional cortical amyloid load, glucose metabolism, cortical morphology (volume),... 相似文献
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Hamre MR Chuba P Bakhshi S Thomas R Severson RK 《Pediatric hematology and oncology》2002,19(5):309-317
Using population-based data from the Surveillance Epidemiology and End Results Program of the National Cancer Institute, melanoma occurring during childhood was evaluated. Compared to adult cases of melanoma, childhood cases had a higher proportion of females (61%) and non-Caucasians (6.5%). The incidence of melanoma increased 85% among 15- to 19-year-olds from 1973 to 1996. Incidence for 15- to 19-year-olds was higher in southern (23.9/million) than northern registries (14.5/million). Non-Caucasians had 3-30% of the cases expected compared to Caucasians. Overall survival of children/adolescents with melanoma was 89% and 79% at 5 and 20 years post diagnosis, respectively. The majority of deaths were directly attributed to melanoma (72%). 相似文献
6.
Phosrithong N Samee W Nunthanavanit P Ungwitayatorn J 《Chemical biology & drug design》2012,79(6):981-989
Forty-eight chromone derivatives were evaluated for their antioxidant activity using 2,2-diphenyl-1-picrylhydrazyl free radical scavenging assay, ferrous ions (Fe(2+) ) chelating activity test, total antioxidant activity test (Ferric thiocyanate and Thiobarbituric acid methods), and total reductive capability (potassium ferricyanide reduction). 7,8-Dihydroxy-2-(3'-trifluoromethylphenyl)-3-(3″-trifluoromethylbenzoyl) chromone 32 showed stronger radical scavenging and metal chelating activities than butylated hydroxytoluene, vitamin E, and trolox. Chromone derivatives that exhibited good radical scavenging and metal chelating also displayed strong total antioxidant and reductive power activities. The results obtained from this study indicated that the synthesized chromone derivatives have remarkable antioxidant activity. 相似文献
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Alibhai MK Samee A Ahmed M Duffield R 《International journal of surgery case reports》2011,2(6):131-133
We report a case of a sixty year old man with a mycotic infra-renal abdominal aortic aneurysm complicated by a left psoas abscess. After treatment with parenteral antibiotics he underwent early aortic reconstruction with an in-situ prosthetic graft wrapped in an omental pedicle. Mycotic abdominal aortic aneurysms can be treated in this way despite the potential for graft infection from persisting retroperitoneal sepsis. 相似文献
9.
Management of rectal cancer has evolved over the years. In this condition preoperative investigations assist in deciding the optimal treatment. The relation of the tumor edge to the circumferential margin (CRM) is an important factor in deciding the need for neoadjuvant treatment and determines the prognosis. Those with threatened or involved margins are offered long course chemoradiation to enable R0 surgical resection. Endoanal ultrasound (EUS) is useful for tumor (T) staging; hence EUS is a useful imagin... 相似文献
10.
Katchamart Wanruchada Narongroeknawin Pongthorn Phutthinart Nattharadee Srinonprasert Varalak Muangpaisan Weerasak Chaiamnauy Sumapa 《Clinical rheumatology》2019,38(7):1851-1856
Clinical Rheumatology - To investigate the association between disease activity and cognitive impairment in patients with rheumatoid arthritis (RA). A total of 464 patients from the rheumatoid... 相似文献