全文获取类型
收费全文 | 10193篇 |
免费 | 547篇 |
国内免费 | 115篇 |
专业分类
耳鼻咽喉 | 48篇 |
儿科学 | 232篇 |
妇产科学 | 299篇 |
基础医学 | 1146篇 |
口腔科学 | 144篇 |
临床医学 | 759篇 |
内科学 | 2571篇 |
皮肤病学 | 278篇 |
神经病学 | 978篇 |
特种医学 | 413篇 |
外科学 | 1834篇 |
综合类 | 26篇 |
一般理论 | 1篇 |
预防医学 | 355篇 |
眼科学 | 146篇 |
药学 | 642篇 |
中国医学 | 29篇 |
肿瘤学 | 954篇 |
出版年
2024年 | 16篇 |
2023年 | 77篇 |
2022年 | 229篇 |
2021年 | 285篇 |
2020年 | 184篇 |
2019年 | 215篇 |
2018年 | 286篇 |
2017年 | 196篇 |
2016年 | 263篇 |
2015年 | 332篇 |
2014年 | 422篇 |
2013年 | 554篇 |
2012年 | 847篇 |
2011年 | 806篇 |
2010年 | 538篇 |
2009年 | 436篇 |
2008年 | 711篇 |
2007年 | 713篇 |
2006年 | 645篇 |
2005年 | 630篇 |
2004年 | 596篇 |
2003年 | 479篇 |
2002年 | 458篇 |
2001年 | 57篇 |
2000年 | 49篇 |
1999年 | 54篇 |
1998年 | 93篇 |
1997年 | 57篇 |
1996年 | 62篇 |
1995年 | 56篇 |
1994年 | 61篇 |
1993年 | 44篇 |
1992年 | 41篇 |
1991年 | 45篇 |
1990年 | 42篇 |
1989年 | 19篇 |
1988年 | 23篇 |
1987年 | 17篇 |
1986年 | 18篇 |
1985年 | 13篇 |
1984年 | 23篇 |
1983年 | 27篇 |
1982年 | 12篇 |
1981年 | 12篇 |
1980年 | 13篇 |
1979年 | 8篇 |
1978年 | 10篇 |
1977年 | 9篇 |
1969年 | 5篇 |
1965年 | 5篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
1.
Vincenzo Levi Andrea Franzini Andrea Di Cristofori Giulio Bertani Mauro Pluderi 《The journal of spinal cord medicine》2020,43(5):714-718
Context: Treatment of primary spinal syringomyelia is still controversial. Among others, shunting syrinx fluid to the subarachnoid, peritoneal or pleural space has been utilized with varying success. Shunt obstruction, migration, and infection represent the most common complications of these procedures. Findings: The authors present the case of an 81-year-old woman who developed an unusual neurological deterioration resembling a subacute posttraumatic ascending myelopathy (SPAM) after the insertion of a syringosubarachnoid shunt for the treatment of slow-growing D10 syringomyelia. Conclusion/Clinical Relevance: To date, no cases of SPAM secondary to the insertion of a syringosubarachnoid shunt for the treatment of syringomyelia have been reported. The potential pathogenesis related to this phenomenon is discussed. 相似文献
2.
Rocco Spagnuolo Alessandro Corea Mariantonietta Blumetti Alessia Giovinazzo Massimiliano Serafino Caterina Pagliuso Raffaele Pagnotta Grazia Curto Cristina Cosco Vincenzo Cosco Rosellina Margherita Mancina Pietro Garieri Anna Papaleo Laura Grande Anna Barilaro Eugenio Garofalo Andrea Bruni Patrizia Doldo 《Journal of advanced nursing》2020,76(11):2993-3002
3.
Elisa Giani Andrea Enzo Scaramuzza Gian Vincenzo Zuccotti 《World journal of diabetes》2015,6(8):999-1004
Technologies for diabetes management, such as continuous subcutaneous insulin infusion (CSII) and continuous glucose monitoring (CGM) systems, have improved remarkably over the last decades. These developments are impacting the capacity to achieve recommended hemoglobin A1c levels and assisting in preventing the development and progression of micro- and macro vascular complications. While improvements in metabolic control and decreases in risk of severe and moderate hypoglycemia have been described with use of these technologies, large epidemiological international studies show that many patients are still unable to meet their glycemic goals, even when these technologies are used. This editorial will review the impact of technology on glycemic control, hypoglycemia and quality of life in children and youth with type 1 diabetes. Technologies reviewed include CSII, CGM systems and sensor-augmented insulin pumps. In addition, the usefulness of advanced functions such as bolus profiles, bolus calculators and threshold-suspend features will be also discussed. Moreover, the current editorial will explore the challenges of using these technologies. Indeed, despite the evidence currently available of the potential benefits of using advanced technologies in diabetes management, many patients still report barriers to using them. Finally this article will highlight the importance of future studies tailored toward overcome these barriers to optimizing glycemic control and avoiding severe hypoglycemia. 相似文献
4.
Maria Ricci Agostino Chiaravalloti Alessandro Martorana Giacomo Koch Vincenzo De lucia Gaetano Barbagallo Orazio Schillaci 《Annals of nuclear medicine》2020,34(4):254-262
The aim of our study was to investigate the impact of the epsilon phenotype in brain glucose consumption in a population with Alzheimer’s disease. Statistical Parametric Mapping (SPM8) was used to investigate differences in brain glucose consumption (as detectable by means of 18F FDG-PET/CT) in the population examined. A total of 129 patients (72 females and 57 males) with a diagnosis of probable AD according to the NINCDS-ADRDA criteria underwent the PET/CT examination. The mean (SD) age of the patients was 70 (± 7) years; the mean Mini-Mental State Examination was 19(± 5.6). 59 expressed epsilon 4 phenotype (E4) and 70 expressed the epsilon 3 phenotype (E3). Cerebral spinal fluid amyloid, tau, and t-tau have been measured resulting equal to 367.4 (± 149.1), 584.7 (± 312.1), and 79.2(± 45.9) pg/ml, respectively. Patients with confirmed amyloid and Tau changes were classified as AD. Patients with amyloid changes but negative Tau, considered as high risk of AD, were classified as IAD. Age, sex, MMSE, scholarship, and CSF parameters were used as a covariate in the SPM analyses. We did not find significant differences in age, gender, and MMSE and CSF parameters among groups. In the analysis of the AD group as compared to AD-E3, AD-E4 subjects show a significant reduction of brain glucose consumption in inferior frontal gyrus bilaterally (BA 45, BA 47). In the analysis of the IAD group as compared to IAD-E3, IAD-E4 subjects show a significant reduction of brain glucose consumption in right in medial, middle, and superior frontal gyrus (BA10, BA11), and in left medial and middle frontal gyrus (BA10, BA11). The differences between IAD-E3 and AD-E3 and between IAD-E4 and AD-E4 (and vice versa analysis) resulted not significant. APO-e4 is related to a major involvement of the frontal cortex confirming its role of risk factor in AD, while APO-3 seems not related to a specific pattern, supporting the hypothesis of neutral/protective role in AD. 相似文献
5.
6.
Using complexity theory to build interventions that improve health care delivery in primary care
下载免费PDF全文
![点击此处可从《Journal of general internal medicine》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Litaker David Tomolo Anne Liberatore Vincenzo Stange Kurt C. Aron David 《Journal of general internal medicine》2006,21(2):S30-S34
Previous observational research confirms abundant variation in primary care practice. While variation is sometimes viewed as problematic, its presence may also be highly informative in uncovering ways to enhance health care delivery when it represents unique adaptations to the values and needs of people within the practice and interactions with the local community and health care system. We describe a theoretical perspective for use in developing interventions to improve care that acknowledges the uniqueness of primary care practices and encourages flexibility in the form of intervention implementation, while maintaining fidelity to its essential functions. 相似文献
7.
Solyakov Lev Dobrota Dušan Drany Oleg Vachova Milena Machač Stanislav Mezešova Viera Bachurin Sergey Lombardi Vincenzo 《Molecular and chemical neuropathology / sponsored by the International Society for Neurochemistry and the World Federation of Neurology and research groups on neurochemistry and cerebrospinal fluid》1995,25(2-3):123-134
Molecular and chemical neuropathology - Changes in the functioning of the glutamatergic system in rabbit brain were studied after partial brain ischemia and reperfusion. In vitro studies were... 相似文献
8.
Isolated pure dislocations of the fifth carpo-metacarpal joint are extremely rare injuries. The dorsal form was described
in mere 12 cases. The diagnosis can be easily missed. The lesion is also often overlooked in the routine diagnostic X-ray.
Lateral and oblique views are important for the recognition of the true extent of the lesion. Treatment of these injures is
still controversial and both closed reduction with percutaneous pinning or open reduction with internal fixation are advocated.
The goal of treatment is early reduction and fixation of the metacarpal. Early diagnosis is the key to success. The aim of
this paper is to review literature and present two new cases. 相似文献
9.
Vincenzo Neri Antonio Ambrosi Giuseppe Di Lauro Tiziano Pio Valentino 《JSLS, Journal of the Society of Laparoendoscopic Surgeons》2006,10(1):66-69
OBJECTIVES: The aim of this study was to evaluate the safety and effectiveness of laparoscopic-assisted sigmoid colectomy for diverticulitis and to assess its postoperative advantages. METHODS: From 1999 to 2001, 5 patients were selectively operated on with a laparoscopic-assisted procedure for uncomplicated sigmoid diverticulitis. In the preceding period (September 1997 through December 1998), 4 patients underwent open procedures for the same pathology. The surgical indication with the same criteria was restrictive: at least 2 acute episodes had occurred that were treated with hospital admission and that were separated by an adequate period (2 months) of medical therapy. RESULTS: No conversions of laparoscopy to an open procedure were necessary. Age, sex, weight, morbidity, and mortality were similar between the 2 groups. Operative time was 180 minutes for laparoscopy and 120 minutes for laparotomy. Postoperative resumption of peristalsis was 24 hours versus 4 days, resumption of alimentation was on the second postoperative day versus the fifth postoperative day, and hospital stay was 7 days versus 12 days for laparoscopy and laparotomy, respectively. CONCLUSION: This study shows the feasibility and the advantages of elective laparoscopic-assisted colonic resection for uncomplicated sigmoid diverticulitis. The advantages of the laparoscopic approach are the lower need for analgesics and the more precocious ambulation, canalization, resumption of alimentation, and the shorter hospital stay. 相似文献
10.