全文获取类型
收费全文 | 1870篇 |
免费 | 111篇 |
国内免费 | 58篇 |
专业分类
耳鼻咽喉 | 19篇 |
儿科学 | 78篇 |
妇产科学 | 15篇 |
基础医学 | 257篇 |
口腔科学 | 139篇 |
临床医学 | 186篇 |
内科学 | 416篇 |
皮肤病学 | 58篇 |
神经病学 | 91篇 |
特种医学 | 310篇 |
外科学 | 100篇 |
综合类 | 29篇 |
预防医学 | 127篇 |
眼科学 | 21篇 |
药学 | 118篇 |
中国医学 | 9篇 |
肿瘤学 | 66篇 |
出版年
2023年 | 18篇 |
2022年 | 29篇 |
2021年 | 32篇 |
2020年 | 30篇 |
2019年 | 38篇 |
2018年 | 44篇 |
2017年 | 30篇 |
2016年 | 30篇 |
2015年 | 29篇 |
2014年 | 51篇 |
2013年 | 81篇 |
2012年 | 87篇 |
2011年 | 85篇 |
2010年 | 72篇 |
2009年 | 88篇 |
2008年 | 65篇 |
2007年 | 102篇 |
2006年 | 59篇 |
2005年 | 59篇 |
2004年 | 37篇 |
2003年 | 28篇 |
2002年 | 33篇 |
2001年 | 20篇 |
2000年 | 20篇 |
1999年 | 30篇 |
1998年 | 82篇 |
1997年 | 82篇 |
1996年 | 105篇 |
1995年 | 63篇 |
1994年 | 60篇 |
1993年 | 54篇 |
1992年 | 21篇 |
1991年 | 19篇 |
1990年 | 21篇 |
1989年 | 38篇 |
1988年 | 38篇 |
1987年 | 36篇 |
1986年 | 47篇 |
1985年 | 42篇 |
1984年 | 11篇 |
1983年 | 17篇 |
1982年 | 13篇 |
1981年 | 9篇 |
1980年 | 11篇 |
1979年 | 10篇 |
1978年 | 14篇 |
1977年 | 11篇 |
1976年 | 13篇 |
1975年 | 13篇 |
1970年 | 3篇 |
排序方式: 共有2039条查询结果,搜索用时 15 毫秒
1.
Mariela Dutra Gontijo Moura Soraya de Mattos Camargo Grossmann Linaena Méricy da Silva Fonseca Maria Inês Barreiros Senna Ricardo Alves Mesquita 《Journal of oral pathology & medicine》2006,35(6):321-326
BACKGROUND: Oral hairy leukoplakia (OHL) may be an indicator of the progression of Human Immunodeficiency Virus (HIV)-induced immuno-depression, and the evaluation of risk factors leading to OHL is important in the management of these HIV-infected patients. However, there are few studies that analyze risk factors leading to OHL in the Brazilian population. The aim of this case-control study is to present data about prevalence rates and risk factors leading to OHL in a sample of HIV-infected adults in Brazil. METHODS: This case-control study included 111 HIV-infected patients treated at a clinic for sexually transmitted diseases and HIV. In the initial examinations with dentists, variables were collected from all patients. Diagnosis of OHL was performed in accordance with the International Classification System and cytological features. The Fisher and the chi-squared tests were used for statistical analysis. The proportional prevalence and odds ratio were estimated. RESULTS: Outcome presented a positive, statistically significant association among the presence of OHL and viral load of 3000 copies/mul or greater (P = 0.0001; odds ratio (OR) = 5.8), presence of oral candidiasis (P = 0.0000; OR = 11.1), previous use of fluconazole (P = 0.0000; OR = 24.6), and use of systemic acyclovir (P = 0.032; OR = 4.3). Antiretroviral medication presented a negative, statistically significant association with the presence of OHL (P = 0.002; OR = 8.4). CONCLUSIONS: Prevalence of OHL was 28.8%. Viral load, oral candidiasis, previous use of fluconazole, and systemic acyclovir were determined to be risk factors for OHL. Antiretroviral medication proved to be protective against the development of OHL. 相似文献
2.
3.
4.
5.
Leonidas JC; Berdon WE; Valderrama E; Neveling U; Schuval S; Weiss SJ; Hilfer C; Godine L 《Radiology》1996,198(2):377
6.
JC Sitek† M Loeb‡ JR Ronnevig¶ 《Journal of the European Academy of Dermatology and Venereology》2007,21(7):891-896
BACKGROUND: Since 1997, a number of trials have shown promising results in treating generalized vitiligo with narrowband ultraviolet B (UVB) both in adults and children. However, there is little knowledge concerning the duration and permanency of the treatment-induced repigmentation. OBJECTIVE: Our main objective was to perform a follow-up trial of successfully treated patients receiving narrowband UVB for generalized vitiligo. METHODS: We have investigated to what degree the treatment-induced repigmentation remains stable for up to 2 years post-treatment. We performed an initial open trial including 31 patients with generalized vitiligo. They received narrowband UVB thrice weekly for up to 12 months. Patients experiencing > 75% repigmentation were defined responders and were included in the follow-up trial. Responders were followed every 6 months for up to 2 years after cessation of treatment. We observed the pigmentation status and registered any changes indicating loss of pigmentation and relapse. RESULTS: Eleven of the 31 treated patients were included in the follow-up trial. Six patients had relapse and five patients had stable response 24 months after cessation of treatment. Four out of six relapses were within 6 months post-treatment. CONCLUSION: In our study population of 31 patients with generalized vitiligo, five patients (16%) experienced > 75% stable repigmentation 2 years after cessation of a treatment programme of up to 1 years narrowband UVB therapy. 相似文献
7.
Ongoing pregnancies after intracytoplasmic injection using cryopreserved testicular spermatozoa 总被引:4,自引:2,他引:2
Perraguin-Jayot S; Audebert A; Emperaire JC; Parneix I 《Human reproduction (Oxford, England)》1997,12(12):2706-2709
We report two clinical pregnancies occurring after intracytoplasmic sperm
injection (ICSI) using cryopreserved spermatozoa obtained from testicular
biopsy, made in two different infertility situations in our clinic. The
first patient showed a secretory azoospermia associated with elevated serum
follicular stimulating hormone (FSH) level and spermiogenesis maturation
arrest. The second patient was affected by azoospermia resulting from
bilateral epididymal obstruction. Spermatozoa present in the wet
preparation of testicular biopsy made on the day of scrotal exploration
were cryopreserved within the testicular tissue for both men.
Intracytoplasmic injections were performed at a later date, using
spermatozoa prepared from frozen-thawed tissues. In each case, three
embryos were obtained and transferred in utero. The transfers resulted in a
twin pregnancy for the first case, and in a singleton pregnancy for the
second. Living foetuses were seen in the ultrasound scan at the 7th week
and both pregnancies are proceeding to date beyond 30 weeks without
complications.
相似文献
8.
9.
10.
Epidemiology of ambiguous genitalia in South America 总被引:1,自引:0,他引:1
E E Castilla I M Orioli R Lugarinho G Dutra 《American journal of medical genetics》1987,27(2):337-343