全文获取类型
收费全文 | 6453篇 |
免费 | 493篇 |
国内免费 | 24篇 |
专业分类
耳鼻咽喉 | 30篇 |
儿科学 | 216篇 |
妇产科学 | 133篇 |
基础医学 | 927篇 |
口腔科学 | 98篇 |
临床医学 | 703篇 |
内科学 | 1492篇 |
皮肤病学 | 108篇 |
神经病学 | 689篇 |
特种医学 | 152篇 |
外科学 | 767篇 |
综合类 | 73篇 |
一般理论 | 1篇 |
预防医学 | 635篇 |
眼科学 | 84篇 |
药学 | 480篇 |
中国医学 | 15篇 |
肿瘤学 | 367篇 |
出版年
2024年 | 7篇 |
2023年 | 85篇 |
2022年 | 101篇 |
2021年 | 253篇 |
2020年 | 165篇 |
2019年 | 226篇 |
2018年 | 234篇 |
2017年 | 171篇 |
2016年 | 201篇 |
2015年 | 218篇 |
2014年 | 255篇 |
2013年 | 328篇 |
2012年 | 474篇 |
2011年 | 509篇 |
2010年 | 259篇 |
2009年 | 223篇 |
2008年 | 407篇 |
2007年 | 389篇 |
2006年 | 423篇 |
2005年 | 369篇 |
2004年 | 350篇 |
2003年 | 300篇 |
2002年 | 228篇 |
2001年 | 64篇 |
2000年 | 48篇 |
1999年 | 69篇 |
1998年 | 52篇 |
1997年 | 41篇 |
1996年 | 39篇 |
1995年 | 37篇 |
1994年 | 25篇 |
1993年 | 13篇 |
1992年 | 37篇 |
1991年 | 44篇 |
1990年 | 47篇 |
1989年 | 38篇 |
1988年 | 23篇 |
1987年 | 20篇 |
1986年 | 23篇 |
1985年 | 16篇 |
1984年 | 15篇 |
1983年 | 14篇 |
1982年 | 14篇 |
1979年 | 19篇 |
1978年 | 7篇 |
1976年 | 8篇 |
1975年 | 8篇 |
1974年 | 9篇 |
1968年 | 6篇 |
1967年 | 10篇 |
排序方式: 共有6970条查询结果,搜索用时 31 毫秒
1.
2.
Philippe A. Eigenmann Motohiro Ebisawa Matthew Greenhawt Jonathan O’B Hourihane Tamara T. Perry Benjamin C. Remington Robert A. Wood 《Pediatric allergy and immunology》2021,32(4):658-666
Risk is a concept inherent in every medical procedure. It can be defined as the probability of an adverse event in a defined population over a specified period of time. In the frame of food allergy management, it might be related to a diagnostic procedure, a treatment, or the consumption of foods. The risk of an adverse event can also be augmented by individual factors. This rostrum article discusses various aspects faced by children with food allergies in the light of risk, and their practical implications. Identifying personal risks for severe reaction, such as unstable asthma, and correcting them whenever possible also contribute to a reduction of the risk inherent to food allergy. Among the facets discussed, oral food challenges (OFC) are the most common diagnostic procedures implying an inherent risk. The risk of OFCs can be minimized by correct indication and timing of the test, a safe setting, as well as by ensuring that the patient is otherwise well without potential stressor potentially increasing the risk of a more severe reaction. Oral immunotherapy (OIT) has been studied as a potential treatment for increasing the threshold dose for reaction, and thus reducing the risk of accidental reaction. Nevertheless, the procedure is not devoid of risk as the patients may and do often react during the course of the procedure. Ingestion of trace amounts in processed foods, mainly in community settings such as restaurants, schools, or day care, represents a potential risk of reactions, although for a minority of patients. Precautionary allergen labeling (PAL) is a widespread strategy to reduce the potential risk of reactions due to traces. However, PAL is currently inefficient due to inconsistent labeling, also not indicating a clear maximum amount possibly present in the manufactured food. Finally, cost-effectiveness needs to be considered in risk management, as many risk reduction procedures are clearly not cost-effective. 相似文献
3.
4.
Edbert B Hsu Tamara L Thomas Eric B Bass Dianne Whyne Gabor D Kelen Gary B Green 《BMC medical education》2006,6(1):19-9
Background
Although training and education have long been accepted as integral to disaster preparedness, many currently taught practices are neither evidence-based nor standardized. The need for effective evidence-based disaster training of healthcare staff at all levels, including the development of standards and guidelines for training in the multi-disciplinary health response to major events, has been designated by the disaster response community as a high priority. We describe the application of systematic evidence-based consensus building methods to derive educational competencies and objectives in criteria-based preparedness and response relevant to all hospital healthcare workers. 相似文献5.
Ophira Salomon Joseph Moisseiev Tamara Vilganski Rima Dardik Shimon Kurtz Eva Shpringer David M Steinberg Nurit Rosenberg 《Blood coagulation & fibrinolysis》2006,17(6):485-488
To determine whether polymorphisms of platelet surface glycoprotein associated with arterial thrombosis are risk factors for branch retinal vein occlusion. A case-control study in which 69 patients with branch retinal vein occlusion and 147 controls who attended the eye clinic for nonvascular complications participated. DNA was extracted from whole blood and analyzed for genotyping of platelet glycoprotein polymorphisms by polymerase chain reactions and specific restricted enzymes. No relationship was found between the four platelet glycoprotein polymorphisms i.e. GPIa C807T, VNTR and Kozak of glycoprotein Ibalpha, the HPA-1 of glycoprotein IIIa and the occurrence of branch retinal vein occlusion. The HPA-2 polymorphism was found in 18 out 60 (30%) patients with branch retinal vein occlusion in comparison with 27 out 142 (19%) of controls, with an estimated odds ratio of 1.8 (95% confidence interval, 0.91-3.65). The four platelet glycoprotein polymorphisms are not risk factors for branch retinal vein occlusion and therefore it seems unnecessary to screen those patients for it. A larger study is required, however, to determine whether HPA-2 is a novel risk factor for branch retinal vein occlusion. 相似文献
6.
Annie Mathieu Stéphanie Mazza Dominique Petit Anne Décary Jessica Massicotte-Marquez Jacques Malo Jacques Montplaisir 《Clinical neurophysiology》2007,118(7):1538-1544
OBJECTIVE: The aim of this study was to determine whether EEG slowing is more pronounced in older than younger OSAS patients and to verify whether this cortical slowing is correlated to daytime performance, respiratory perturbation and sleep fragmentation. METHODS: Twelve young OSAS patients (mean age 38.2+/-2.0 y) and 13 older OSAS patients (mean age 62.2+/-1.9 y) along with 13 young controls (mean age 35.8+/-2.0 y) and 14 older controls (mean age 60.2+/-2.0 y) underwent a polysomnographic evaluation followed by a waking EEG recording. As a global index of cortical slowing, a ratio of slow-to-fast frequencies was calculated in all cortical regions. Daytime performance was assessed using the four choice reaction time test. RESULTS: Differences in waking EEG and in daytime performance were analyzed by ANOVAs with Group and Age as factors. Waking EEG did not yield a Group by Age interaction. OSAS patients had higher ratios across all regions than controls. Similarly, daytime performance revealed no Group by Age interaction. However, OSAS patients showed more lapses than controls and older subjects were slower than younger subjects. CONCLUSIONS: Our results indicate that age does not interact with OSAS to worsen the severity of cortical slowing, but age can add to the OSAS effect to worsen daytime performance deficits in OSAS patients. SIGNIFICANCE: The daytime performance deficits observed particularly in elderly OSAS patients warrant a careful clinical assessment of these patients to prevent accidents and injuries. 相似文献
7.
Shelley Allen Glenys Carlson Tamara Ownsworth Jenny Strong 《Australian Occupational Therapy Journal》2006,53(4):293-301
Aim: To present an evidence-based framework to improve the quality of occupational therapy expert opinions on work capacity for litigation, compensation and insurance purposes.
Methods: Grounded theory methodology was used to collect and analyse data from a sample of 31 participants, comprising 19 occupational therapists, 6 medical specialists and 6 lawyers. A focused semistructured interview was completed with each participant. In addition, 20 participants verified the key findings.
Results: The framework is contextualised within a medicolegal system requiring increasing expertise. The framework consists of (i) broad professional development strategies and principles, and (ii) specific strategies and principles for improving opinions through reporting and assessment practices.
Conclusions: The synthesis of the participants' recommendations provides systematic guidelines for improving occupational therapy expert opinion on work capacity. 相似文献
Methods: Grounded theory methodology was used to collect and analyse data from a sample of 31 participants, comprising 19 occupational therapists, 6 medical specialists and 6 lawyers. A focused semistructured interview was completed with each participant. In addition, 20 participants verified the key findings.
Results: The framework is contextualised within a medicolegal system requiring increasing expertise. The framework consists of (i) broad professional development strategies and principles, and (ii) specific strategies and principles for improving opinions through reporting and assessment practices.
Conclusions: The synthesis of the participants' recommendations provides systematic guidelines for improving occupational therapy expert opinion on work capacity. 相似文献
8.
M Luigia Vaccario Maria A Valenti Anna Carullo Rossella Di Bartolomeo Salvatore Mazza 《Clinical EEG》2003,34(1):15-17
Benign neonatal sleep myoclonus (BNSM), characterized by myoclonic jerks of the extremities only in non-REM sleep, occurs in the first months of life with spontaneous disappearance within 3-4 months. We examined five siblings with typical BNSM, at the 3-10 years follow-up neurological examination. Psychomotor development, cognitive functions and EEG were completely normal. These cases confirm that BNSM is a self limited and nonepileptic disorder. 相似文献
9.
Central sensory and motor conduction in vitamin B12 deficiency. 总被引:7,自引:0,他引:7
V Di Lazzaro D Restuccia D Fogli R Nardone S Mazza P Tonali 《Electroencephalography and clinical neurophysiology》1992,84(5):433-439
Four patients with subacute combined degeneration were studied through upper and lower limb SEPs recorded with a non-cephalic reference montage and through cortical and spinal magnetic stimulation. Clinical signs were confined to the lower limbs in 3 patients; the remaining patient presented only paraesthesiae in 4 limbs. Median nerve SEPs showed a normal cervical N13 response with a significant increase of central conduction time concerning exclusively the P9-P14 interpeak interval. Central motor conduction to upper and lower limb muscles was abnormal. Nerve conduction studies provided no evidence of peripheral nerve involvement. These electrophysiological findings suggest that in vitamin B12 deficiency the higher segments of the cervical cord are usually affected first and that central sensory and motor conduction studies are sensitive methods for detecting such damage. 相似文献
10.