全文获取类型
收费全文 | 1681篇 |
免费 | 159篇 |
国内免费 | 13篇 |
专业分类
耳鼻咽喉 | 12篇 |
儿科学 | 64篇 |
妇产科学 | 34篇 |
基础医学 | 203篇 |
口腔科学 | 37篇 |
临床医学 | 185篇 |
内科学 | 326篇 |
皮肤病学 | 81篇 |
神经病学 | 164篇 |
特种医学 | 50篇 |
外科学 | 209篇 |
综合类 | 28篇 |
预防医学 | 106篇 |
眼科学 | 66篇 |
药学 | 83篇 |
中国医学 | 18篇 |
肿瘤学 | 187篇 |
出版年
2023年 | 13篇 |
2022年 | 40篇 |
2021年 | 67篇 |
2020年 | 49篇 |
2019年 | 68篇 |
2018年 | 82篇 |
2017年 | 58篇 |
2016年 | 58篇 |
2015年 | 71篇 |
2014年 | 79篇 |
2013年 | 114篇 |
2012年 | 128篇 |
2011年 | 126篇 |
2010年 | 85篇 |
2009年 | 61篇 |
2008年 | 104篇 |
2007年 | 88篇 |
2006年 | 66篇 |
2005年 | 69篇 |
2004年 | 67篇 |
2003年 | 52篇 |
2002年 | 48篇 |
2001年 | 21篇 |
2000年 | 17篇 |
1999年 | 10篇 |
1998年 | 9篇 |
1997年 | 17篇 |
1996年 | 20篇 |
1995年 | 6篇 |
1994年 | 7篇 |
1993年 | 9篇 |
1992年 | 13篇 |
1991年 | 10篇 |
1990年 | 7篇 |
1989年 | 11篇 |
1988年 | 11篇 |
1987年 | 15篇 |
1986年 | 8篇 |
1985年 | 17篇 |
1984年 | 5篇 |
1983年 | 11篇 |
1982年 | 6篇 |
1980年 | 4篇 |
1979年 | 2篇 |
1978年 | 5篇 |
1976年 | 4篇 |
1975年 | 3篇 |
1974年 | 3篇 |
1973年 | 3篇 |
1972年 | 2篇 |
排序方式: 共有1853条查询结果,搜索用时 15 毫秒
1.
2.
Hair Loss after Rhytidectomy 总被引:2,自引:0,他引:2
BACKGROUND: Temporal hair loss has been reported to occur in up to 8.4% of patients after rhytidectomy. To date, no one has described the associated histopathologic findings. OBJECTIVE: The objective was to illustrate the microscopic findings seen in the affected area of hair loss after rhytidectomy. METHODS: Two punch biopsies from the temporal area were performed, and pathologic material was submitted. RESULTS: Histopathologic finding was suggestive of acute localized telogen effluvium. CONCLUSION: One mechanism for temporal hair loss after rhytidectomy is an acute localized telogen effluvium. 相似文献
3.
Marcelo H. Grunwald Boaz Amichai Hani Giryes Sima Halevy 《Journal of the European Academy of Dermatology and Venereology》1997,9(2):166-168
We report a case of erythrodermic type of bullous pemphigoid which is a rare variant of bullous pemphigoid. Our patient had a peculiar clinical presentation with bullae, erosions and extensive erythrodermic areas, and distinct direct immunofluorescent findings which included linear IgG and C3 deposits in the basement membrane and also IgG in the intercellular spaces. Very high levels of serum IgE were also detected in our patient. 相似文献
4.
Sedigheh Sadat Tavafian Ahmadreza Jamshidi Kazem Mohammad Ali Montazeri 《BMC musculoskeletal disorders》2007,8(1):21
Background
Different interventions can reduce the burden of the chronic low back pain. One example is the use of a 'Back School Programme'. This is a brief therapy that uses a health education method to empower participants through a procedure of assessment, education and skill development. This study aimed to evaluate to what extent the programme could improve quality of life in those who suffer from the condition. 相似文献5.
Diabetic autonomic neuropathy in BB rats and effect of ARI treatment on heart-rate variability and vagus nerve structure 总被引:1,自引:0,他引:1
The preventive effect of the aldose reductase inhibitor (ARI) ponalrestat on heart-rate variability and the development of autonomic neuropathy in the vagus nerve was investigated in the spontaneously diabetic BB rat. ARI treatment completely prevented the characteristic decrease in heart-rate variability and axonal atrophy of the vagus nerve for 4 mo in hyperglycemic BB rats. After 6 mo of treatment, the preventive effect on heart-rate variability was partial, and the vagus nerve demonstrated an increase in regenerating myelinated and unmyelinated fibers. These data suggest that autonomic neuropathy involving the vagus nerve is metabolically induced by demonstrating that inhibition of the polyol pathway significantly delays the occurrence of functional and structural autonomic neuropathy despite the presence of hyperglycemia. 相似文献
6.
A PCR Specific for Escherichia coli O157 Based on the rfb Locus Encoding O157 Lipopolysaccharide 总被引:13,自引:0,他引:13
下载免费PDF全文
![点击此处可从《Journal of clinical microbiology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Patricia M. Desmarchelier Sima S. Bilge Narelle Fegan Leanne Mills James C. Vary Jr. Phillip I. Tarr 《Journal of clinical microbiology》1998,36(6):1801-1804
A PCR was developed for the detection of Escherichia coli O157 based on the rfbE O-antigen synthesis genes. A 479-bp PCR product was amplified specifically from E. coli O157 in cell lysates containing 200 or 2 CFU following crude DNA extraction. The PCR detected <1 CFU of E. coli O157 per ml in raw milk following enrichment. 相似文献
7.
Th1 cell development induced by cysteine proteinases A and B in localized cutaneous leishmaniasis due to Leishmania guyanensis
下载免费PDF全文
![点击此处可从《Infection and immunity》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Pascalis H Lavergne A Bourreau E Prévot-Linguet G Kariminia A Pradinaud R Rafati S Launois P 《Infection and immunity》2003,71(5):2924-2926
The cysteine proteinases CPA and CPB from Leishmania major induced Th1 responses in patients with leishmaniasis due to Leishmania guyanensis. Furthermore, cysteine proteinases induced neither interleukin 4 (IL-4) nor IL-13 and low levels of IL-10 in controls and patients. The results suggest that CPs would be quite good candidates for a vaccine against different Leishmania species. 相似文献
8.
9.
The adsorption of carbofuran on sandy clay loam and silt loam soils has been studied at 30 and 50 degrees C. Adsorption data for both soils are in close agreement with the Freundlich isotherms and yield "S" class isotherms. The order of adsorption of carbofuran is in accordance with the partial molal free energy changes and conforms to the mobility of carbofuran in different soils. The thermodynamic constant (K0) and standard free energy (delta G degrees), enthalpy (delta H degrees), and entropy changes (delta S degrees) have also been calculated for predicting the nature of adsorption. 相似文献
10.
Saeed Shoar Fatemeh Sadat Hosseini Azouba Gulraiz Waleed Ikram Moiz Javed Mohammad Naderan Nasrin Shoar Venkat R. Modukuru 《Surgery for obesity and related diseases》2021,17(3):630-643
Even in the hands of highly experienced bariatric surgeons, perioperative complications are inevitable. Of these, leaks and fistulas are amongst the scariest complications. Intrathoracic gastric fistulas (ITGF) can be associated with serious morbidity, mostly when cases are misdiagnosed or detected with delay. This is a systematic review of the literature to investigate the clinical and surgical outcomes of morbidly obese adult patients with a confirmed diagnosis of ITGF following bariatric surgery. A pooled analysis of 25 articles, encompassing 76 patients with post-bariatric ITGF, showed that the clinical outcome depends on the initial presentation, timing of the diagnosis in relation to symptom onset, and prompt and effective treatment. Any septic or unstable patient must undergo urgent surgical intervention, while stable patients might tolerate a step-up approach and watchful waiting for nonsurgical treatment. Among those who undergo surgery, treatment failure and the mortality rate are substantially high. Contingent upon a prompt management strategy, patients with postbariatric ITGF can generally have a favorable outcome in the long term. 相似文献