全文获取类型
收费全文 | 300篇 |
免费 | 38篇 |
国内免费 | 1篇 |
专业分类
耳鼻咽喉 | 3篇 |
儿科学 | 4篇 |
妇产科学 | 8篇 |
基础医学 | 33篇 |
口腔科学 | 10篇 |
临床医学 | 32篇 |
内科学 | 81篇 |
皮肤病学 | 10篇 |
神经病学 | 12篇 |
特种医学 | 8篇 |
外科学 | 47篇 |
综合类 | 11篇 |
预防医学 | 13篇 |
眼科学 | 10篇 |
药学 | 38篇 |
1篇 | |
中国医学 | 3篇 |
肿瘤学 | 15篇 |
出版年
2024年 | 2篇 |
2023年 | 12篇 |
2022年 | 13篇 |
2021年 | 16篇 |
2020年 | 14篇 |
2019年 | 19篇 |
2018年 | 48篇 |
2017年 | 29篇 |
2016年 | 10篇 |
2015年 | 13篇 |
2014年 | 22篇 |
2013年 | 21篇 |
2012年 | 19篇 |
2011年 | 17篇 |
2010年 | 5篇 |
2009年 | 8篇 |
2008年 | 9篇 |
2007年 | 6篇 |
2006年 | 7篇 |
2005年 | 9篇 |
2004年 | 5篇 |
2003年 | 5篇 |
2002年 | 3篇 |
2001年 | 2篇 |
1999年 | 1篇 |
1998年 | 2篇 |
1997年 | 6篇 |
1996年 | 4篇 |
1992年 | 1篇 |
1991年 | 1篇 |
1986年 | 1篇 |
1972年 | 2篇 |
1971年 | 2篇 |
1970年 | 2篇 |
1966年 | 1篇 |
1948年 | 1篇 |
1932年 | 1篇 |
排序方式: 共有339条查询结果,搜索用时 31 毫秒
1.
Ghoreifi Alireza Basin Michael F. Ghodoussipour Saum Bazargani Soroush T. Amini Erfan Aslzare Mohammad Cai Jie Miranda Gus Sugeir Shihab Bhanvadia Sumeet Schuckman Anne K. Daneshmand Siamak Lumb Philip Djaladat Hooman 《International urology and nephrology》2021,53(9):1827-1833
International Urology and Nephrology - The aim of this study is to evaluate the intra/perioperative fluid management and early postoperative outcomes of patients who underwent radical cystectomy... 相似文献
2.
Gamze Erfan Yakup Albayrak M. Emin Yanik Ozden Oksuz Kaan Tasolar Birol Topcu Cuneyt Unsal 《The Journal of dermatology》2014,41(8):709-715
Alopecia areata (AA) and vitiligo (V) are diseases that are correlated with psychiatric disorders before, during and after diagnosis. The Temperament and Character Inventory (TCI) is a well‐established approach for investigating personality traits in various psychosomatic diseases. The aim of this study is to compare and investigate the differences in the TCI between patients with first onset AA, patients with V and healthy controls (HC). Participants in the study included 42 patients with first onset AA, 50 adult patients with V and 60 HC who had no history or diagnoses of psychiatric or dermatological disorders. All participants were assessed with the TCI and the Dermatology Life Quality Index (DLQI). Among the temperament traits, the extravagance, disorderliness and total novelty‐seeking scores were lower, and the worry and pessimism scores were higher in patients with V compared with patients with AA and the HC. The mean score of the enlightened second nature and the total self‐directedness score of the character traits were higher in patients with V compared with patients with AA and the HC group. In the AA group, there was a negative correlation only between the reward dependence total score and the DLQI score. This study suggests that patients with first onset V have a distinct temperament, such as being unenthusiastic and unemotional, and character profiles, such as worry and pessimism, independent of their psychiatric comorbidities, and patients with AA do not have a different personality from the non‐affected population. 相似文献
3.
4.
Prospective evaluation of chronic organ damage in adult sickle cell patients: A seven‐year follow‐up study
下载免费PDF全文
![点击此处可从《American journal of hematology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Charlotte F. J. van Tuijn Marein Schimmel Eduard J. van Beers Erfan Nur Bart J. Biemond 《American journal of hematology》2017,92(10):E584-E590
Organ damage in sickle cell disease (SCD) is a crucial determinant for disease severity and prognosis. In a previous study, we analyzed the prevalence of SCD‐related organ damage and complications in adult sickle cell patients. We now describe a seven‐year follow‐up of this cohort.All patients from the primary analysis in 2006 (n = 104), were included for follow‐up. Patients were screened for SCD‐related organ damage and complications (microalbuminuria, renal failure, elevated tricuspid regurgitation flow velocity (TRV) (≥2.5 m/seconds), retinopathy, iron overload, cholelithiasis, avascular osteonecrosis, leg ulcers, acute chest syndrome (ACS), stroke, priapism and admissions for vaso‐occlusive crises (VOC) biannually. Upon 7 years of follow‐up, progression in the prevalence of avascular osteonecrosis (from 12.5% to 20.4%), renal failure (from 6.7% to 23.4%), retinopathy (from 39.7% to 53.8%) was observed in the whole group. In HbSS/HbSβ0‐thal patients also progression in microalbuminuria (from 34% to 45%) and elevated TRV (from 40% to 48%) was observed while hardly any progression in the prevalence of cholelithiasis, priapism, stroke or chronic ulcers was seen. The proportion of patients with at least one episode of ACS increased in the group of HbSS/HbSβ0‐thal patients from 32% to 49.1%. In conclusion, 62% of the sickle cell patients in this prospective cohort study developed a new SCD‐related complication in a comprehensive care setting within 7 years of follow‐up. Although the hospital admission rate for VOC remained stable, multiple forms of organ damage increased substantially. These observations underline the need for continued screening for organ damage in all adult patients with SCD. 相似文献
5.
Melzer H Fortugno P Mansouri E Felici F Marinets A Wiedermann G Kollaritsch H Von Specht BU Duchêne M 《Parasite immunology》2002,24(6):321-328
Entamoeba histolytica is the protozoan parasite responsible for intestinal amoebiasis and amoebic liver abscess, which cause significant morbidity and mortality in many countries of the world. Proteophosphoglycans (PPGs, also known as lipophosphoglycans, LPGs, or lipopeptidophosphoglycans, LPPGs) represent dominant surface components of E. histolytica. Passive immunization with a monoclonal antibody (EH5) directed against these components protected SCID mice from amoebic liver abscess, so PPGs might be regarded as vaccine candidates; however, their structure is very complex and only known in part. They are glycosylphosphatidylinositol-linked polypeptides of unknown sequence carrying glycan side-chains linked to serine residues via phosphodiester bonds. In order to identify peptide mimics of the E. histolytica PPG antigens, we screened six different phage-displayed random peptide libraries with the antibody EH5. Various peptide mimics of different length were identified and, in all the peptides, a distinct consensus sequence Gly-Thr-His-Pro-X-Leu could be identified. The phages strongly bound to the antibody, and the natural antigen inhibited binding of the phages to antibody EH5. In addition, several of the phages induced a significant immunoglobulin G response against amoebic antigens in immunized mice. 相似文献
6.
Sayeh Ehsani Brian Nebbe David Normando Manuel O Lagravere Carlos Flores-Mir 《The Angle orthodontist》2015,85(6):997
Objective:To compare the short-term skeletal and dental effects of two-phase orthodontic treatment including either a Twin-block or an XBow appliance.Materials and Methods:This was a retrospective clinical trial of 50 consecutive Class II cases treated in a private practice with either a Twin-block (25) or XBow (25) appliance followed by full fixed orthodontic treatment. To factor out growth, an untreated Class II control group (25) was considered.Results:A MANOVA of treatment/observation changes followed by univariate pairwise comparisons showed that the maxilla moved forward less in the treatment groups than in the control group. As for mandibular changes, the corpus length increase was larger in the Twin-block group by 3.9 mm. Dentally, mesial movement of mandibular molars was greater in both treatment groups. Although no distalization of maxillary molars was found in either treatment group, restriction of mesial movement of these teeth was seen in both treatment groups. Both treatment groups demonstrated increased mandibular incisor proclination with larger increases for the XBow group by 3.3°. The Wits value was decreased by 1.6 mm more in the Twin-block group. No sex-related differences were observed.Conclusions:Class II correction using an XBow or Twin-block followed by fixed appliances occurs through a relatively similar combination of dental and skeletal effects. An increase in mandibular incisor inclination for the XBow group and an increased corpus length for the Twin-block group were notable exceptions. No overall treatment length differences were seen. 相似文献
7.
8.
9.
10.