全文获取类型
收费全文 | 1617篇 |
免费 | 71篇 |
国内免费 | 14篇 |
专业分类
耳鼻咽喉 | 31篇 |
儿科学 | 24篇 |
妇产科学 | 9篇 |
基础医学 | 194篇 |
口腔科学 | 39篇 |
临床医学 | 117篇 |
内科学 | 348篇 |
皮肤病学 | 22篇 |
神经病学 | 149篇 |
特种医学 | 57篇 |
外科学 | 362篇 |
综合类 | 8篇 |
预防医学 | 40篇 |
眼科学 | 43篇 |
药学 | 158篇 |
中国医学 | 4篇 |
肿瘤学 | 97篇 |
出版年
2023年 | 7篇 |
2022年 | 27篇 |
2021年 | 44篇 |
2020年 | 25篇 |
2019年 | 26篇 |
2018年 | 34篇 |
2017年 | 21篇 |
2016年 | 29篇 |
2015年 | 33篇 |
2014年 | 50篇 |
2013年 | 65篇 |
2012年 | 107篇 |
2011年 | 106篇 |
2010年 | 55篇 |
2009年 | 48篇 |
2008年 | 80篇 |
2007年 | 71篇 |
2006年 | 83篇 |
2005年 | 81篇 |
2004年 | 64篇 |
2003年 | 74篇 |
2002年 | 59篇 |
2001年 | 47篇 |
2000年 | 41篇 |
1999年 | 35篇 |
1998年 | 20篇 |
1997年 | 18篇 |
1996年 | 12篇 |
1995年 | 12篇 |
1994年 | 10篇 |
1993年 | 10篇 |
1992年 | 29篇 |
1991年 | 28篇 |
1990年 | 25篇 |
1989年 | 30篇 |
1988年 | 12篇 |
1987年 | 20篇 |
1986年 | 16篇 |
1985年 | 23篇 |
1984年 | 12篇 |
1983年 | 14篇 |
1980年 | 9篇 |
1979年 | 12篇 |
1978年 | 9篇 |
1977年 | 6篇 |
1976年 | 8篇 |
1975年 | 5篇 |
1974年 | 8篇 |
1973年 | 7篇 |
1972年 | 7篇 |
排序方式: 共有1702条查询结果,搜索用时 15 毫秒
1.
2.
K Takahashi A Ihaya Y Chiba N Tanikawa R Muraoka 《Kyobu geka. The Japanese journal of thoracic surgery》1990,43(3):236-239
A 34-year-old woman was admitted with an abnormal shadow on a chest X-ray film. Under a preoperative diagnosis of benign bronchogenic cyst, operation was carried out and the tumor was found to be originating from the right main vagal nerve in the mid-superior mediastinum. The vagal nerve was transected to remove the tumor. Pathological diagnosis was a neurinoma. Postoperative complication was chylothorax which was successfully treated with thoracic drainage and intravenous hyperalimentation. 相似文献
3.
Q-Switched Alexandrite Laser Therapy for Pigmentation of the Lips Owing to Laugier-Hunziker Syndrome 总被引:2,自引:0,他引:2
Ozawa Toshiyuki MD Fujiwara Masao MD † Harada Teruichi MD Muraoka Michinari MD Ishii Masamitsu MD 《Dermatologic surgery》2005,31(6):709-712
BACKGROUND: Laugier-Hunziker (LH) syndrome is a rare benign condition in which hyperpigmentation of the lips and buccal mucosa occurs with no systemic associations. OBJECTIVE: We report the response to treatment with the Q-switched alexandrite laser (QSAL) because there are few reports on therapy for LH syndrome. METHODS: The QSAL was used for pigmentation of the lips in a 63-year-old woman with LH syndrome. Laser irradiation was done at 5.0 J/cm2 with a 3 mm spot size. RESULTS: There was 100% clearance of pigmentation of the lips with a single laser treatment, and recurrence was not observed after 6 months. CONCLUSION: The QSAL is very effective for pigmentation owing to LH syndrome. 相似文献
4.
N Shinoura T Kondo I Muraoka Y Tsukamoto M Yoshioka H Miyazawa 《No shinkei geka. Neurological surgery》1990,18(6):557-561
Two cases of sacrococcygeal teratoma in female infants are reported. Case 1. A newborn baby with a hemispheric mass on her hip underwent surgery 3 days after birth and the lesion proved to be an immature teratoma. The serum AFP level was very high but became normal one month after the operation. The child also had agenesis of the corpus callosum and arachnoid cysts in right middle fossa. She died after developing shunt infection. Case 2. A newborn baby with a mature teratoma was operated on the day following birth. The tumor was subtotally removed, and there has been no recurrence after 6 months. Sacrococcygeal teratoma in female infants is often associated with agenesis of the corpus callosum and arachnoid cysts. They tend to develop almost at the same time as the teratoma. It is often difficult to determine whether the infant should be treated by chemotherapy or not if the teratoma is immature, especially when it has been totally removed, the serum AFP is normal, and the tumor is pathologically of a low grade. 相似文献
5.
6.
7.
Safety evaluation of surgical materials by cytotoxicity testing 总被引:2,自引:1,他引:1
The cytotoxicity of three kinds of commercially available absorbable hemostats [oxidized cellulose (Surgicel, gauze and cotton
types), microfibrillar collagen (Avitene), and cotton-type collagen (Integran)] and one adhesion barrier [sodium hyaluronate
and carboxymethyl-cellulose membrane (Seprafilm)] were comparatively assessed by a colony assay using V79 cells and a minimum
essential medium (MEM) elution assay in combination with a neutral red assay using L929 cells. Strong cytotoxicity was detected
for Surgicel by both the MEM elution assay and the colony assay. For Avitene, both methods revealed weak cytotoxicity. For
Seprafilm, no cytotoxicity was detected by the MEM elution assay, while a moderate degree of cytotoxicity was observed in
the colony assay. For Integran cytotoxicity was not detected by either the MEM elution or the colony assay. The results of
the different methods showed some inconsistency in terms of the degree of cytotoxicity of the materials. It is proposed that
the combination of two or more sensitive cytotoxicity testing methods for the evaluation of biomaterials is necessary to avoid
false-negative results for biomaterials at the preclinical stage. Furthermore, investigation of the correlation between the
cytotoxicity and the extraction period of the surgical materials is helpful for predicting the effect of prolonged in vivo
use of biomaterials on surrounding cells, tissues, and organs. 相似文献
8.
Mitsuru Masaki Tadashi Kuroda Naoki Hosen Hisao Hirota Kazuo Terai Yuichi Oshima Yoshikazu Nakaoka Shoko Sugiyama Ryusuke Kimura Satoshi Yoshihara Manabu Kawakami Norishige Iizuka Yasuhiko Tomita Hiroyasu Ogawa Ichiro Kawase Keiko Yamauchi-Takihara 《Journal of the American Society of Echocardiography》2004,17(4):397-398
A 57-year-old man with a history of renal cell carcinoma presented with presyncope. He underwent nephrectomy years earlier followed by HLA-matched allogeneic peripheral-blood stem-cell transplantation. Echocardiographic investigation revealed a solitary right ventricle mass without contiguous vena caval or right atrial involvement. The mass was pathologically confirmed to be metastatic carcinoma in the right ventricular cavity. This case highlights the need to consider an underlying neoplastic syndrome in patients presenting isolated right ventricle mass by echocardiography. 相似文献
9.
Masashi Muraoka Shinji Akamine Tadayuki Oka Tsutomu Tagawa Akihiro Nakamura Tomoshi Tsuchiya Tomayoshi Hayashi Takeshi Nagayasu 《European journal of cardio-thoracic surgery》2007,32(2):356-361
OBJECTIVE: It is controversial whether a systematic mediastinal lymph node dissection (MLND) needs to be performed in all patients with stage I lung cancer. The present study was done to examine the new sentinel lymph nodes hypothesis based on the lobe of the primary tumor. METHODS: In our first study, the lymph node (LN) metastases were assessed in 291 stage I non-small cell lung cancer (NSCLC) patients who had a major lung resection with a systematic mediastinal lymph node dissection. We evaluated the validity of using our new sentinel lymph nodes method based on the lobe of the primary tumor as follows: the pretracheal (#3), tracheobronchial (#4), and hilar nodes (#10) for right upper lobe tumors; #4, subcarinal (#7), and #10 for middle lobe tumors; the subaortic (#5), paraaortic (#6), and #10 for left upper lobe tumors; and the #7, #10, and interlobar nodes (#11) for tumors in either lower lobes. In the second study, we performed a lobectomy with new sentinel node sampling in 64 patients with preoperative complications. If all of the sampling nodes showed no metastases on frozen section diagnosis, systematic node dissections were not performed. RESULTS: Six of 291 patients in the first study had skip metastases that did not involve the new sentinel nodes; 5 of the 6 patients had macroscopic pleural invasion. Thus, we defined pleural invasion as an exclusion criterion for the second study. In the second study, the median follow-up time was 39 months. Metastatic lymph nodes were detected in 11 of 64 patients. Fifty-three patients (83%) had no metastasis in the sampled nodes, and, therefore, a mediastinal lymph node dissection was not done. The morbidity rate in the sampling group was 36%, and there was no mortality. In the sampling group, local recurrences were observed in two patients, distant metastases in eight, and carcinomatous pleuritis in one; the overall 5-year survival rate was 82%. CONCLUSIONS: We found that it is possible to perform a less invasive lymphadenectomy for patients with stage I lung cancer using intra-operative sampling of new sentinel lymph nodes. 相似文献
10.