全文获取类型
收费全文 | 1690篇 |
免费 | 85篇 |
国内免费 | 2篇 |
专业分类
耳鼻咽喉 | 28篇 |
儿科学 | 133篇 |
妇产科学 | 83篇 |
基础医学 | 252篇 |
口腔科学 | 28篇 |
临床医学 | 135篇 |
内科学 | 253篇 |
皮肤病学 | 12篇 |
神经病学 | 78篇 |
特种医学 | 37篇 |
外科学 | 239篇 |
综合类 | 53篇 |
一般理论 | 1篇 |
预防医学 | 95篇 |
眼科学 | 84篇 |
药学 | 183篇 |
中国医学 | 12篇 |
肿瘤学 | 71篇 |
出版年
2023年 | 17篇 |
2022年 | 37篇 |
2021年 | 56篇 |
2020年 | 35篇 |
2019年 | 49篇 |
2018年 | 64篇 |
2017年 | 32篇 |
2016年 | 47篇 |
2015年 | 53篇 |
2014年 | 57篇 |
2013年 | 77篇 |
2012年 | 77篇 |
2011年 | 79篇 |
2010年 | 69篇 |
2009年 | 55篇 |
2008年 | 86篇 |
2007年 | 93篇 |
2006年 | 96篇 |
2005年 | 98篇 |
2004年 | 79篇 |
2003年 | 60篇 |
2002年 | 52篇 |
2001年 | 49篇 |
2000年 | 47篇 |
1999年 | 33篇 |
1998年 | 14篇 |
1997年 | 12篇 |
1996年 | 11篇 |
1995年 | 6篇 |
1994年 | 4篇 |
1993年 | 4篇 |
1992年 | 19篇 |
1991年 | 14篇 |
1990年 | 14篇 |
1989年 | 19篇 |
1988年 | 23篇 |
1987年 | 14篇 |
1986年 | 8篇 |
1985年 | 12篇 |
1984年 | 15篇 |
1983年 | 7篇 |
1980年 | 7篇 |
1979年 | 13篇 |
1978年 | 6篇 |
1976年 | 11篇 |
1975年 | 5篇 |
1974年 | 10篇 |
1973年 | 3篇 |
1972年 | 7篇 |
1968年 | 5篇 |
排序方式: 共有1777条查询结果,搜索用时 15 毫秒
1.
2.
A 50-yr-old man presented with synovitis of the metacarpophalangealjoints, Raynaud's phenomenon, recurrent pericarditis and a linearpalpable rash in both axillae. 相似文献
3.
4.
Pratipal Singh Vivek Vijjan Manu Gupta Deepak Dubey Aneesh Srivastava 《International journal of urology》2007,14(6):558-560
Congenital thoracic ectopic kidney is a very rare developmental anomaly and the rarest form of all ectopic kidneys. It is usually asymptomatic and discovered incidentally on routine chest radiography. Herein we reported the first case of staghorn stone in a thoracic kidney managed successfully by percutaneous nephrolithotomy. 相似文献
5.
6.
Sturge-Weber syndrome is a rare neurocutaneous disorder characterized by a facial nevus flammeus and extensive angiomatous changes involving the leptomeninges, the dura, and vessels of the gray and white matter. Oculodermal melanocytosis is characterized by hyperpigmentation of the facial skin in the distribution of the ophthalmic, maxillary, and occasionally mandibular division of the trigeminal nerve. 相似文献
7.
Y. N. Mchra S. B. S. Mann S. P. Dubey A. Verma S. Suri 《Indian journal of otolaryngology and head and neck surgery》1989,41(2):43-47
Due to deep seated location and presence of vital structures, the tumours of the parapharyngeal space poses difficulty in
its early diagnosis, histological nature and surgical extirpation. Modes of radiological assessment in pre-computed tomography
(GT) scan era were sialography of the parotid gland to see whether the tumour is of salivary origin and angiography to note
the vascularity of the tumour. Post CT scan era has changed the assessment protocol. In this article, the authors have tried
to make a comparative evalua?tion between non-contrast GT, GT with systemic contrast and GT sialogram in 14 cases of parapharyngeal
tumours. Angiography was done only when the tumours showed marked enhancement with systemic contrast. Subsequently, 13 patients
underwent surgery for removal of the mass. Application of high-resolution GT helped in not only to see the extent of the tumour
but also to pinpoint the probable histologic nature. 相似文献
8.
9.
Wetzel DM Schmidt J Kuhlenschmidt MS Dubey JP Sibley LD 《Infection and immunity》2005,73(9):5379-5387
We examined gliding motility and cell invasion by an early-branching apicomplexan, Cryptosporidium parvum, which causes diarrheal disease in humans and animals. Real-time video microscopy demonstrated that C. parvum sporozoites undergo circular and helical gliding, two of the three stereotypical movements exhibited by Toxoplasma gondii tachyzoites. C. parvum sporozoites moved more rapidly than T. gondii sporozoites, which showed the same rates of motility as tachyzoites. Motility by C. parvum sporozoites was prevented by latrunculin B and cytochalasin D, drugs that depolymerize the parasite actin cytoskeleton, and by the myosin inhibitor 2,3-butanedione monoxime. Imaging of the initial events in cell entry by Cryptosporidium revealed that invasion occurs rapidly; however, the parasite does not enter deep into the cytosol but rather remains at the cell surface in a membrane-bound compartment. Invasion did not stimulate rearrangement of the host cell cytoskeleton and was inhibited by cytochalasin D, even in host cells that were resistant to the drug. Our studies demonstrate that C. parvum relies on a conserved actin-myosin motor for motility and active penetration of its host cell, thus establishing that this is a widely conserved feature of the Apicomplexa. 相似文献
10.
Structures of Toxoplasma gondii Tachyzoites, Bradyzoites, and Sporozoites and Biology and Development of Tissue Cysts 总被引:4,自引:0,他引:4
下载免费PDF全文
![点击此处可从《Clinical microbiology reviews》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Infections by the protozoan parasite Toxoplasma gondii are widely prevalent worldwide in animals and humans. This paper reviews the life cycle; the structure of tachyzoites, bradyzoites, oocysts, sporocysts, sporozoites and enteroepithelial stages of T. gondii; and the mode of penetration of T. gondii. The review provides a detailed account of the biology of tissue cysts and bradyzoites including in vivo and in vitro development, methods of separation from host tissue, tissue cyst rupture, and relapse. The mechanism of in vivo and in vitro stage conversion from sporozoites to tachyzoites to bradyzoites and from bradyzoites to tachyzoites to bradyzoites is also discussed. 相似文献