全文获取类型
收费全文 | 26349篇 |
免费 | 1526篇 |
国内免费 | 196篇 |
专业分类
耳鼻咽喉 | 236篇 |
儿科学 | 1369篇 |
妇产科学 | 358篇 |
基础医学 | 3074篇 |
口腔科学 | 434篇 |
临床医学 | 1729篇 |
内科学 | 4871篇 |
皮肤病学 | 485篇 |
神经病学 | 1757篇 |
特种医学 | 989篇 |
外国民族医学 | 5篇 |
外科学 | 3890篇 |
综合类 | 884篇 |
一般理论 | 5篇 |
预防医学 | 1650篇 |
眼科学 | 1303篇 |
药学 | 2512篇 |
5篇 | |
中国医学 | 328篇 |
肿瘤学 | 2187篇 |
出版年
2023年 | 131篇 |
2022年 | 312篇 |
2021年 | 648篇 |
2020年 | 390篇 |
2019年 | 507篇 |
2018年 | 586篇 |
2017年 | 469篇 |
2016年 | 560篇 |
2015年 | 585篇 |
2014年 | 891篇 |
2013年 | 1131篇 |
2012年 | 1646篇 |
2011年 | 1719篇 |
2010年 | 974篇 |
2009年 | 820篇 |
2008年 | 1318篇 |
2007年 | 1356篇 |
2006年 | 1235篇 |
2005年 | 1171篇 |
2004年 | 1044篇 |
2003年 | 1075篇 |
2002年 | 926篇 |
2001年 | 679篇 |
2000年 | 674篇 |
1999年 | 616篇 |
1998年 | 288篇 |
1997年 | 256篇 |
1996年 | 217篇 |
1995年 | 207篇 |
1994年 | 165篇 |
1993年 | 169篇 |
1992年 | 384篇 |
1991年 | 406篇 |
1990年 | 366篇 |
1989年 | 407篇 |
1988年 | 295篇 |
1987年 | 317篇 |
1986年 | 252篇 |
1985年 | 271篇 |
1984年 | 235篇 |
1983年 | 208篇 |
1982年 | 130篇 |
1981年 | 118篇 |
1979年 | 190篇 |
1978年 | 126篇 |
1975年 | 136篇 |
1974年 | 143篇 |
1973年 | 137篇 |
1972年 | 123篇 |
1971年 | 144篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
3.
4.
Subacute sclerosing panencephalitis (SSPE) is a rare, slowly progressing but invariably fatal disease that is related to a prior measles virus infection and most commonly affects paediatric patients. Magnetic resonance (MR) imaging is the modality of choice for determining such changes in white matter. SSPE typically demonstrates bilateral but asymmetric periventricular and subcortical white matter involvement. We herein report a rare case of unilateral white matter involvement in a 13-year-old boy with SSPE that closely simulated Rasmussen’s encephalitis. To the best of our knowledge, this is the first report of an atypical presentation on MR imaging in which SSPE was a rare cause of unilateral brain parenchymal involvement in a patient with intractable seizures. 相似文献
5.
Roberto V.P. Ribeiro Mitesh V. Badiwala Danny Ramzy Laura C. Tumiati Vivek Rao 《The Journal of thoracic and cardiovascular surgery》2019,157(2):615-625.e1
Objective
Hypertonic saline (HTS) has potent immune and vascular effects. We assessed recipient pretreatment with HTS on allograft function in a porcine model of heart transplantation and hypothesized that HTS infusion would limit endothelial and left ventricular (LV) dysfunction following transplantation.Methods
Heart transplants were performed after 6 hours of cold ischemic storage. Recipient pigs were randomized to treatment with or without HTS (7.5% NaCl) before cardiopulmonary bypass (CPB). Using a myograft apparatus, coronary artery endothelial-dependent (Edep) and -independent (Eind) relaxation was assessed. LV performance was determined using pressure-volume loop analysis. Pulmonary interleukin (IL)-2, IL-6, and tumor necrosis factor (TNF)-α expression was measured.Results
Weaning from CPB and LV performance after transplantation were improved in HTS-treated animals. Successful weaning from CPB was greater in the HTS-treated hearts (8 of 8 vs 2 of 8; P < .05). Mean LV functional recovery was improved in the HTS-treated animals, as assessed by preload recruitable stroke work (65 ± 10% vs 27 ± 10%; P < .001) and end-systolic elastance (55 ± 7% vs 37 ± 4%; P < .001). Treatment with HTS resulted in improved Edep (mean maximum elastance [Emax], 56 ± 5% vs 37 ± 7%; P < .001) and Eind (mean Emax%, 77 ± 6% vs 52 ± 4%; P < .001) vasorelaxation compared with control. Pulmonary expression of IL-2, IL-6, and TNF-α increased following transplantation, whereas HTS therapy attenuated IL production (P < .001). Transplantation increased plasma TNF-α levels and LV TNF-α expression, whereas HTS prevented this up-regulation (P < .001).Conclusions
Recipient HTS pretreatment preserves allograft vasomotor and LV function, and HTS therapy limits CPB-induced injury. HTS may be a novel recipient intervention to prevent graft dysfunction. 相似文献6.
7.
8.
目的:观察中西医结合治疗排卵障碍性不孕症的疗效。方法:82例按随机数字表法分为对照组和观察组各41例。两组均给予常规西药治疗,观察组加用腹针温阳法治疗。结果:受孕成功率观察组84.44%,对照组71.11%,两组比较差异有统计学意义(P<0.05)。观察组优质卵泡直径小于对照组(P<0.05),优质卵泡数量以及子宫内膜厚度均高于对照组(P<0.05)。两组卵巢动脉血流PI、RI、PSV与EDV指标均优于治疗前(P<0.05),且观察组各项指标均优于对照组(P<0.05)。结论:中西医结合治疗排卵障碍性不孕症可改善卵泡发育以及卵巢动脉血流指标,提高受孕率。 相似文献
10.
Parupudi V J Sriram Guduru V Rao Nageshwar D Reddy 《Indian journal of gastroenterology》2006,25(1):39-41
Endoscopic clips have been used mainly for control of gastrointestinal (GI) bleeding and occasionally for closure of GI perforations. However, closure of spontaneous esophageal perforation (Boerhaave's syndrome) by clipping has not been reported. We described successful non-surgical closure of spontaneous esophageal perforation by endoscopic clipping in a patient with bilateral pyopneumothorax and septicemia. 相似文献