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1.
Iu A Popova L B Buravkova B N Pavlov 《Aviakosmicheskaia i ekologicheskaia meditsina》2005,39(5):31-36
Several metabolic and hormonal parameters were evaluated in blood of two human subjects during simulation of an extended saturation dive. Increases in creatine kinase and an upward trend in cholesterol and glucose were observed after decompression. The levels of TTH and thyroxin went up in both subjects during exposure. The significant changes in cortisol, ACTH, insulin and C-peptide were a fingerprint of stress-reaction. After eight days of recovery most of the parameters returned to baseline values. The investigation suggests that the recompression treatment table did not cause pathological changes in the biochemical and hormonal parameters of humans. 相似文献
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E. N. Popova 《Bulletin of experimental biology and medicine》1996,122(4):1056-1058
Alterations occurring in the neurons of rat sensorimotor cortex 1, 2, and 4 months after a 4-month alcohol intoxication and
1 and 4 months after a 1-year alcoholization are studied by the methods of Nissl and Golgi. Pronounced dystrophic changes
in cortical neurons and dendrites as well as reparative processes in the cell body are revealed 1 month after a 4-month intoxication.
The recovery period for the upper cortical layer neurons (phylogenetically younger) is faster than that of neurons from the
lower layers (phylogenetically older), as well as that of hypochromatousvs. hyperchromatous cells. Normalization of dendrite structure is slower than that of the cell body. Four months after a 1-year
alcohol intoxication the structure of cortical neurons and dendrites is not restored.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 122, No. 10, pp. 467–470, October, 1996 相似文献
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N. Ya. Popova A. I. Antokhin N. V. Adrianov L. Z. Tret'yakova Yu. A. Romanov 《Bulletin of experimental biology and medicine》1991,112(4):1486-1488
Department of Biology, Medico-Biological Faculty, and Applied Research Laboratory of Ecology, Toxicology, and Metabolism of Medicinal Preparations, attached to the Department of Biochemistry, Medico-Biological Faculty, N. I. Pirogov Second Moscow Medical Institute. Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 112, No. 10, pp. 418–419, October, 1991. 相似文献
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Central Scientific-Research Institute for Tuberculosis. Institute for Problems of Information Transmission, Moscow. Translated from Meditsinskaya Tekhnika, No. 3, pp. 30–32, May–June, 1992. 相似文献
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All cells that constitute mature tissues in an eukaryotic organism undergo a multistep process of cell differentiation. At
the terminal stage of this process, cells either cease to proliferate forever or rest for a very long period of time. During
terminal differentiation, most of the genes that are required for cell ‘housekeeping’ functions, such as proto-oncogenes and
other cell-cycle and cell proliferation genes, become stably repressed. At the same time, nuclear chromatin undergoes dramatic
morphological and structural changes at the higher-order levels of chromatin organization. These changes involve both constitutively
inactive chromosomal regions (constitutive heterochromatin) and the formerly active genes that become silenced and structurally
modified to form facultative heterochromatin. Here we approach terminal cell differentiation as a unique system that allows
us to combine biochemical, ultrastructural and molecular genetic techniques to study the relationship between the hierarchy
of chromatin higher-order structures in the nucleus and its function(s) in dynamic packing of genetic material in a form that
remains amenable to regulation of gene activity and other DNA-dependent cellular processes. 相似文献