全文获取类型
收费全文 | 25806篇 |
免费 | 1248篇 |
国内免费 | 176篇 |
专业分类
耳鼻咽喉 | 199篇 |
儿科学 | 526篇 |
妇产科学 | 439篇 |
基础医学 | 2820篇 |
口腔科学 | 618篇 |
临床医学 | 2052篇 |
内科学 | 6768篇 |
皮肤病学 | 486篇 |
神经病学 | 2973篇 |
特种医学 | 775篇 |
外科学 | 3873篇 |
综合类 | 43篇 |
一般理论 | 5篇 |
预防医学 | 1086篇 |
眼科学 | 451篇 |
药学 | 1453篇 |
中国医学 | 30篇 |
肿瘤学 | 2633篇 |
出版年
2024年 | 26篇 |
2023年 | 172篇 |
2022年 | 389篇 |
2021年 | 747篇 |
2020年 | 444篇 |
2019年 | 616篇 |
2018年 | 691篇 |
2017年 | 550篇 |
2016年 | 620篇 |
2015年 | 690篇 |
2014年 | 1013篇 |
2013年 | 1270篇 |
2012年 | 1995篇 |
2011年 | 1991篇 |
2010年 | 1156篇 |
2009年 | 1067篇 |
2008年 | 1747篇 |
2007年 | 1809篇 |
2006年 | 1668篇 |
2005年 | 1647篇 |
2004年 | 1628篇 |
2003年 | 1352篇 |
2002年 | 1322篇 |
2001年 | 194篇 |
2000年 | 114篇 |
1999年 | 150篇 |
1998年 | 252篇 |
1997年 | 211篇 |
1996年 | 200篇 |
1995年 | 171篇 |
1994年 | 132篇 |
1993年 | 130篇 |
1992年 | 113篇 |
1991年 | 93篇 |
1990年 | 88篇 |
1989年 | 71篇 |
1988年 | 71篇 |
1987年 | 68篇 |
1986年 | 59篇 |
1985年 | 58篇 |
1984年 | 78篇 |
1983年 | 44篇 |
1982年 | 45篇 |
1981年 | 43篇 |
1980年 | 33篇 |
1979年 | 20篇 |
1978年 | 16篇 |
1977年 | 30篇 |
1976年 | 17篇 |
1974年 | 15篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
1.
2.
3.
Chiara Tanzi Gaia Fallani Francesco Magnani Giovanni Marozza Silvia Pizzarotti Bruno Zoppi Davide Lazzeroni Lorenzo Brambilla Paolo Coruzzi Luca Moderato 《La Medicina del lavoro》2020,111(2):107
Background:Cardiovascular diseases (CVD), particularly the ischemic heart disease, are a growing public health issue. In addition, the return to work after an acute cardiovascular attack represents a complex challenge.Objectives:To evaluate utility and safety of cardiopulmonary exercise testing (CPET), particularly performed “on site”, to promote a return to work in line with the residual working capacity.Methods:Fifty-nine workers affected by a major cardiovascular event, aged 18-63 years, have been enrolled between 2015 and 2018. All the patients underwent a CPET in outpatient clinic. Eleven workers also underwent the “on site” CPET, recorded during their working activities.Results:Outpatient clinic CPET outcomes (i.e. normal, mild impairment or moderate/severe impairment of cardiopulmonary function) were associated with the subjective perception of workers’ health status after returning to work. The “on site” CPET was found to be safe and reliable to promote a personalized return to work of patients. In 7 out of 11 patients, the values of O2 consumption (VO2) during the working activity were higher than 40% of VO2 max as obtained from laboratory CPET.Conclusions:This study provides evidence for safety and usefulness of “on site” CPET for a personalized statement of fitness for work. This may facilitate the job retention of patients characterized by a high risk of unnecessary job loss. The use of CPET represents a first step of energy expenditure evaluation associated with specific working tasks.Key words: Acute coronary syndrome, cardiopulmonary exercise testing, return to work 相似文献
4.
Maria Stella Aniello Davide Martino Gianluca Masi Paolo Livrea Giovanni Defazio 《Movement disorders》2006,21(4):571-575
We developed a self-administered questionnaire for screening the most common adult-onset dystonias. It was tested in 90 first-degree relatives of 22 adult-onset dystonia patients, yielding 79% sensitivity and 94% specificity. Simulation of a case-finding procedure based on serial application of the questionnaire and clinical examination of both subjects screening positive and subjects screening negative who had < 8 years of schooling increased sensitivity to 95% and specificity to 100%. This questionnaire may be an important screening resource for familial aggregation studies to be used in the context of a complex case-finding procedure. 相似文献
5.
R Rosso F Boccardo F Brema M R Sertoli D Amoroso G Bertelli P Pronzato 《Anticancer research》1989,9(4):1153-1156
131 patients with resectable, node-positive breast cancer were treated at the National Institute for Cancer Research of Genoa, Italy with a systemic adjuvant regimen based on 14 cycles of chemotherapy, immunostimulation with levamisole, and--for postmenopausal patients--hormone therapy with tamoxifen. The present evaluation is performed eleven years after the admission of the first patient: so far, 75 patients (57.3%) have relapsed and 52 (39.7%) have died. An analysis of prognostic factors for relapse and death shows that the number of positive axillary lymph nodes and the dimension of the primary tumor are significantly associated with survival and relapse-free survival, while age and menopausal status are not. 相似文献
6.
Nicola Martinelli Domenico Girelli Paolo Ferraresi Oliviero Olivieri Barbara Lunghi Franco Manzato Roberto Corrocher Francesco Bernardi 《Blood coagulation & fibrinolysis》2007,18(2):125-129
A common factor V gene haplotype, the FVR2 haplotype (FVHR2), has been associated with a reduced cofactor activity in activated protein C-mediated activated factor VIII inactivation. Our aim was to investigate the role of FVHR2 as a possible determinant of factor VIII levels in a population study. A total of 516 individuals (401 men, 115 women; mean age 58.4 +/- 10.8 years) were enrolled within the frame of a regional cardiovascular survey, characterized for factor VIII coagulant activity (FVIII:c) and factor V coagulant activity (FV:c) levels, and genotyped for factor V polymorphisms. In men without signs of overt inflammation, FVHR2 carriers had higher levels of FVIII:c than noncarriers (154 IU/dl, 95% confidence interval = 143-166 versus 142 IU/dl, 95% confidence interval = 138-147; P = 0.045) and were more represented in individuals with high (> or = 150 IU/dl) FVIII:c levels (21.2 versus 10.8%; odds ratio = 2.27, 95% confidence interval = 1.17-4.39 after adjustment for age, blood group and high-sensitivity C-reactive protein levels). In conclusion, this clinical report suggests the common FVHR2 as a possible independent determinant of FVIII:c levels. The report concomitantly addresses the relationship between factor V and factor VIII levels and supports the hypothesis of a mild prothrombotic role of FVHR2 by means of increased factor VIII levels. 相似文献
8.
9.
Angelo M. Carella Sandro Nati Paolo Carlier Daniela Pierluigi Domenico Giordano Angela Congiu Gino Santini Daniele Scarpati Salvina Barra Renzo Corvo Vito Vitale Maria R. Raffo Raffaella Cerri Marco Risso Mauro Spriano Renato Vimercati Ester Pungolino Andrea Bacigalupo Eugenio Damasio 《Leukemia & lymphoma》1991,5(1):43-47
Forty consecutive adult patients under the age of 50 with acute non-lymphoblastic leukemia (ANLL) in first complete remission, underwent autologous bone marrow transplantation (ABMT) between March 1984 and April 1990. The conditioning regimen employed included cyclophosphamide and total body irradiation, followed by the administration of unpurged ABMT. The median time from diagnosis to transplant was 7 months (3-15 months), and the median time from complete remission to ABMT was 4 months (range 3-9 months). Twenty-two (51%) patients remain in complete remission 6-81 months (median 24 months) after ABMT.
The causes of death were, recurrent leukemia (11 patients), parenchymal toxicities such as acute respiratory distress syndrome and veno-occlusive disease (3 patients), hemorrhage (2 patients) and infection (2 patients). Eleven patients relapsed after 3-12 months (median 5 months). This study has produced survival data comparable to those of other institutions employing TBI for either allo or autotransplants. 相似文献
The causes of death were, recurrent leukemia (11 patients), parenchymal toxicities such as acute respiratory distress syndrome and veno-occlusive disease (3 patients), hemorrhage (2 patients) and infection (2 patients). Eleven patients relapsed after 3-12 months (median 5 months). This study has produced survival data comparable to those of other institutions employing TBI for either allo or autotransplants. 相似文献
10.