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排序方式: 共有598条查询结果,搜索用时 218 毫秒
1.
Sonoelasticity imaging of prostate cancer: in vitro results 总被引:2,自引:0,他引:2
2.
Background: Increasingly larger series of laparoscopic fundoplications (LF) are being reported. A well-documented advantage of the laparoscopic
approach is shortened hospital stay. Most centers report typical lengths of stay (LOS) for LF of 2–3 days. Our success with
LF with a LOS of 1 day led to an attempt at performing LF on an ambulatory basis.
Methods: Sixty-one consecutive patients with appropriate criteria for LF underwent surgery at our institution. Patients were counseled
by the authors as to the usual postop course and progression of diet. All patients received preemptive analgesia (PEA) consisting
of perioperative ketorolac and preincisional local infiltration with bupivicaine. Anesthetic management included induction
with propofol, high-dose inhalational anesthetics, minimizing administration of parenteral narcotics, and avoidance of reversal
of neuromuscular blockade. Immediate postop pain management included parenteral ketorolac and oral hydro- or oxycodone. All
patients were given oral fluids and soft solids after transfer from the recovery room to the postoperative observation unit.
Two patients were excluded from ambulatory consideration due to excessive driving distance from our hospital. Another two
were hospitalized for observation after experiencing intraoperative technical problems.
Results: Of 57 patients in whom same-day discharge was attempted, there were three failures requiring overnight hospitalization: All
were due to pain and nausea; one patient also suffered transient urinary retention. There were no adverse outcomes related
to early discharge, and there were no readmissions. One patient returned to the emergency room after delayed development of
urinary retention. Median time from conclusion of operation to discharge was less than 5 h. No patients expressed dissatisfaction
with early discharge on follow-up interview.
Conclusions: LF can be safely performed as an ambulatory procedure. Analgesic and anesthetic management should be tailored to minimize
nausea and provide adequate pain control.
Received: 1 April 1996/Accepted: 29 May 1997 相似文献
3.
Screening for early ovarian cancer 总被引:5,自引:0,他引:5
4.
The vascularity of 49 renal masses (26 malignant and 23 benign lesions) was investigated with duplex Doppler ultrasound. Doppler signals obtained at the margins of renal masses were defined as "tumor signals" when the Doppler-shifted frequency of the lesion exceeded the frequency shift in the ipsilateral main renal artery. These exceeded 2.5 kHz with a 3-MHz insonating frequency. Among the 26 renal masses that subsequently proved to be malignant, tumor signals were obtained in 15 of 18 (83%) untreated renal cell carcinomas, in three of four Wilms tumors, and in two patients with metastases to the kidney, but not in the one patient with lymphoma. None of the 23 benign renal masses demonstrated tumor signals. Tumor vascularity in malignant lesions gives rise to abnormal, high-velocity, Doppler-shifted signals that can help in the differential diagnosis of renal masses. 相似文献
5.
Detection of reactive oxygen species (ROS) and apoptosis in human fragmented embryos 总被引:8,自引:2,他引:8
Yang HW; Hwang KJ; Kwon HC; Kim HS; Choi KW; Oh KS 《Human reproduction (Oxford, England)》1998,13(4):998-1002
In human in-vitro fertilization (IVF)-embryo transfer, the in-vitro culture
environment differs from in-vivo conditions in that the oxygen
concentration is higher, and in such conditions the mouse embryos show a
higher concentration of reactive oxygen species (ROS) in simple culture
media. ROS are believed to cause damage to cell membranes and DNA
fragmentation in somatic cells. This study was conducted to ascertain the
level of H2O2 concentration within embryos and the morphological features
of cell damage induced by H2O2. A total of 62 human oocytes and embryos (31
fragmented, 15 non-fragmented embryos, 16 unfertilized oocytes) was
obtained from the IVF-embryo transfer programme. The relative intensity of
H2O2 concentrations within embryos was measured using
2',7'-dichlorodihydrofluorescein diacetate by Quanti cell 500 fluorescence
imaging and DNA fragmentation was observed with transmission electron
microscopy and an in-situ apoptosis detection kit. The H2O2 concentrations
were significantly higher in fragmented embryos (72.21 +/- 9.62, mean +/-
SEM) compared to non-fragmented embryos (31.30 +/- 3.50, P < 0.05) and
unfertilized oocytes (30.75 +/- 2.67, P < 0.05). Apoptosis was observed
only in fragmented embryos, and was absent in non-fragmented embryos.
Electron microscopic findings confirmed apoptotic bodies and cytoplasmic
condensation in the fragmented blastomeres. We conclude that there is a
direct relationship between increased H2O2 concentration and apoptosis, and
that further studies should be undertaken to confirm these findings.
相似文献
6.
7.
Pathways to care for alcohol use disorders 总被引:1,自引:0,他引:1
8.
Recently the spectrum of dressings was enriched, incorporating the so-called hydrogel dressing, made by Geistlich Sons Ltd. and Byk Goldbin-Konstanz referred to as "Geliperm". In Poland, HDR hydrogel dressings' technology was launched by Institute of Radiative Technology, Lód?+ Polytechnic. This type of dressing is obtained by radiative cross-linking of hydrophilic polymers. The experimental studies of the new Polish hydrogel materials were accomplished at the Department of Experimental Surgery and Biomaterials Research, the Chair of traumatologic Surgery, Medical Academy of Wroc?aw. These studies concerned three kinds of hydrogel dressings, different in composition and irradiation conditions. HDR-1 10% of polyvinylpyrrolidone+, 1.5% of agar, 1.5% of polyethylene glycol 300, irradiated with 30 kGy (gamma radiation of 60Co); HDR-1 with neomycin--formula as above plus neomycin sulfate (2.5%); HDR-2 6% of polyvinylpyrrolidone++, 1% of agar, 1.5% of polyethylene glycol 300, irradiated with 25-27 kGy (gamma radiation of 60Co). The usable properties of the HDR dressings approximate those of the West German products. Owing to the lab tests, biological and in vitro examinations we had performed, it was possible to state that aqueous extracts of the hydrogel dressings subjected to assessment did'nt exhibit hemolytical or toxic activities in cellular tests, at the same time lacking an irritating effect. They cause a minimal tissular reaction and accelerate the process of healing. 相似文献
9.
10.
A Hodgkin cell-specific antigen is expressed on a subset of auto- and alloactivated T (helper) lymphoblasts 总被引:21,自引:0,他引:21
A Hodgkin cell-specific antigen detected by the monoclonal antibody Ki- 1 was found on T helper lymphocytes after activation by autologous and allogeneic stimulator cells. About 50% of lymphoblasts generated by auto- and alloactivation reacted with the antibody. In contrast, only less than 6% of lymphoblasts stimulated with Con-A, phytohemagglutinin (PHA), or protein A, and none of lymphoblasts activated by oxidative mitogenesis, expressed this antigen. Among several permanent cell lines tested, the K562, MOLT-4, HL-60, and EBV transformed B lymphoblastoid cells reacted with the Ki-1 antibody. The results may indicate possible relationships between the autoreactive subset of T lymphocytes and the pathogenesis of Hodgkin's disease. 相似文献