全文获取类型
收费全文 | 8874篇 |
免费 | 607篇 |
国内免费 | 46篇 |
专业分类
耳鼻咽喉 | 84篇 |
儿科学 | 294篇 |
妇产科学 | 216篇 |
基础医学 | 1032篇 |
口腔科学 | 266篇 |
临床医学 | 711篇 |
内科学 | 2030篇 |
皮肤病学 | 182篇 |
神经病学 | 559篇 |
特种医学 | 223篇 |
外国民族医学 | 8篇 |
外科学 | 1414篇 |
综合类 | 297篇 |
一般理论 | 3篇 |
预防医学 | 653篇 |
眼科学 | 173篇 |
药学 | 766篇 |
中国医学 | 96篇 |
肿瘤学 | 520篇 |
出版年
2023年 | 118篇 |
2022年 | 253篇 |
2021年 | 441篇 |
2020年 | 237篇 |
2019年 | 301篇 |
2018年 | 321篇 |
2017年 | 235篇 |
2016年 | 288篇 |
2015年 | 316篇 |
2014年 | 399篇 |
2013年 | 476篇 |
2012年 | 676篇 |
2011年 | 747篇 |
2010年 | 418篇 |
2009年 | 342篇 |
2008年 | 489篇 |
2007年 | 432篇 |
2006年 | 449篇 |
2005年 | 456篇 |
2004年 | 369篇 |
2003年 | 315篇 |
2002年 | 294篇 |
2001年 | 93篇 |
2000年 | 90篇 |
1999年 | 107篇 |
1998年 | 53篇 |
1997年 | 46篇 |
1996年 | 35篇 |
1995年 | 51篇 |
1994年 | 38篇 |
1993年 | 41篇 |
1992年 | 44篇 |
1991年 | 23篇 |
1990年 | 40篇 |
1989年 | 42篇 |
1988年 | 33篇 |
1987年 | 39篇 |
1986年 | 35篇 |
1985年 | 25篇 |
1984年 | 20篇 |
1983年 | 26篇 |
1982年 | 28篇 |
1981年 | 22篇 |
1980年 | 15篇 |
1979年 | 17篇 |
1978年 | 24篇 |
1976年 | 14篇 |
1973年 | 14篇 |
1972年 | 15篇 |
1969年 | 15篇 |
排序方式: 共有9527条查询结果,搜索用时 15 毫秒
1.
2.
Dipankar Nandi Helen Smith Sarah Owen Carole Joint John Stein Tipu Aziz 《Journal of clinical neuroscience》2002,9(5):557-561
Central post stroke pain is often difficult to manage satisfactorily with conventional treatment modalities for pain. In the last decade functional neurosurgery has offered hope with motor cortex stimulation achieving significant alleviation of pain in some patients. Unfortunately this has led to the neglect of chronic stimulation of deep grey matter as another modality of treating this condition. In this article we present our experience with motor cortex stimulation and that with deep grey matter stimulation in patients with post stroke pain. We argue that both modalities have a significant role and that what is required are better methods of identifying particular patients who are more likely to respond to one or the other. 相似文献
3.
4.
Ruhangiz T. Kilani ; Larry Guilbert ; Xiaoyue Lin ; Aziz Ghahary 《Wound repair and regeneration》2007,15(2):236-244
Overexpression of wound healing-promoting factors such as transforming growth factor-1 (TGF-beta1) and insulin-like growth factor-1 (IGF-1) during the healing process has been implicated in the development of dermal fibrosis in patients following thermal injury, surgical incision, and deep trauma. However, the mechanism through which the expression of these two fibrogenic factors is slowed down and/or abrogated in the late stages of the healing process is not known. Here, we hypothesize that keratinocyte-releasable factors counteract the fibrogenic role of both IGF-1 and TGF-beta1 in fibroblasts. To test this hypothesis, the levels of collagenase (MMP-1), as an index for extracellular matrix degradation, in dermal fibroblasts in response to either keratinocyte-conditioned medium (KCM) or our recently identified keratinocyte-releasable stratifin in the presence and absence of either IGF-1, TGF-beta1, or both were evaluated. The results of Northern analysis showed a significant increase in collagenase mRNA expression in cells treated with KCM in the presence of both IGF-1 and TGF-beta1. The effect was, at least in part, due to keratinocyte-derived stratifin that was present in KCM. This was ascertained as the levels of MMP-1 mRNA were markedly reduced when cells were treated with stratifin-immuno-depleted KCM. The results of Western blot analysis showed an increase in the level of MMP-1 protein in stratifin-treated fibroblasts and this was consistent with the level of MMP-1 mRNA expression detected by Northern analysis. However, in contrast to KCM, whose efficacy on MMP-1 expression was modestly reduced by either IGF-1 and TGF-beta1, or a combination of both, these factors abrogated the MMP-1 stimulatory effect of stratifin in fibroblasts. In summary, the results of this study revealed that both stratifin and KCM stimulate the expression of MMP-1-in fibroblasts and this effect can be abrogated by either IGF-1, TGF-beta1, or a combination of both. 相似文献
5.
Sami Al-Said Ammar Ali Abdul Kader Alobaidy Emad Mojeeb Abdulla Al-Naimi Ahmed A Shokeir 《International journal of urology》2007,14(5):452-454
Xanthogranulomatous orchitis is an extremely rare inflammatory non-neoplastic destructive lesion of the testis. We report a 44-year-old man who presented with right scrotal swelling and two discharging sinuses. Testicular tumor markers were normal. Scrotal ultrasound showed heterogeneous testicular areas and irregular margin of the tunica. Surgical exploration revealed infected, unhealthy testicular tissue with necrosis and tumor-like lesion. Orchidectomy was done and histopathology showed xanthogranulomatous orchitis. 相似文献
6.
S. Aziz L. A. Soine S. L. Lewis A. P. Kruse W. C. Levy K. M. Wehe D. P. Fishbien M. D. Allen 《Transplant international》1997,10(6):446-450
A review of factors contributing to early mortality after cardiac transplantation revealed that up to 25 % of deaths were
due to primary graft dysfunction unrelated to rejection or infection. In light of this finding, evaluation of a donor heart
with regard to its suitability for transplantation takes on added importance. In an effort to screen the suitability of donor
hearts in the region covered by the Northwest Organ Procurement Agency (USA), all donors are evaluated by two-dimensional
transthoracic echocardiography as part of the initial evaluation. A total of 110 donor echocardiograms were reviewed and an
attempt was made to correlate the 30-day outcome with the parameters measured. An unexpected finding was that the presence
of left ventricular hypertrophy in the donor heart was associated with an increase in the incidence of donor heart dysfunction
compared with donors with normal echocardiographic profiles (33 % vs 3 %, P = 0.007).
Received: 12 February 1996 Received after resision: 27 June 1997 Accepted: 14 July 1997 相似文献
7.
8.
Conference Reports: This section contains reports on topical conferences. Reports are usually written at the request of the editorial office, but unsolicited contributions are also welcome. Suggestions should be sent to the editorial office of the Macromolecular journals, preferably by E‐mail to macromol@wiley‐vch.de. 相似文献
9.
Abdul Ahad 《Indian journal of otolaryngology and head and neck surgery》1997,49(4):341-343
Tumours of the nerve sheath origin in the head and neck are not common. Schwannomas are rare. Only a few cases have been reported so far. We report a rare case of Schwannoma of Submandibular region arising from the lingual nerve. 相似文献
10.