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排序方式: 共有1201条查询结果,搜索用时 15 毫秒
1.
Alternative splicing: a mechanism for phenotypic rescue of a common inherited defect. 总被引:11,自引:2,他引:9 下载免费PDF全文
H Morisaki T Morisaki L K Newby E W Holmes 《The Journal of clinical investigation》1993,91(5):2275-2280
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QuickVue Influenza Test for Rapid Detection of Influenza A and B Viruses in a Pediatric Population 下载免费PDF全文
Caroline Quach Diane Newby Ghislaine Daoust Earl Rubin Jane McDonald 《Clinical and Vaccine Immunology : CVI》2002,9(4):925-926
The performance of a lateral-flow immunoassay, the QuickVue Influenza Test, for detection of influenza A and B viruses in comparison with that of cell culture was evaluated by using nasopharyngeal aspirates, in viral transport medium, from children with respiratory tract infections. The sensitivity and specificity were 79.2 and 82.6%, respectively. 相似文献
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Ross BD; Jacobson S; Villamil F; Korula J; Kreis R; Ernst T; Shonk T; Moats RA 《Radiology》1994,193(2):457
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Altered polyvinylpyrrolidone clearance and immune responsiveness caused by small dietary changes. 下载免费PDF全文
The introduction of 25 mg of a new protein antigen into the diets of mice produced transient increases in PVP clearance which reached a maximum 60 hr after the change of diet and had disappeared by 4 days. At the same time the immune responsiveness to unrelated antigens given parenterally was also raised transiently, reaching a peak 5 days following the change and disappearing by 7 days. In contrast the responsiveness to the fed antigen was diminished. 相似文献
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Effect of cold exposure, exercise and high altitude on plasma endothelin-1 and endothelial cell markers in man 总被引:1,自引:0,他引:1
The aims were to examine the effect of cold exposure, exercise and high altitude on plasma concentrations of big endothelin-1, endothelin-1, von Willebrand factor and serum e-selectin in twenty five healthy male volunteers. Clinical evaluation and venesection were performed before and after 24 hours of low altitude mountaineering, exposure to temperatures of -18 degrees C and +4 degrees C and whilst ascending from sea level to an altitude of 5000 m in the Karakoram. Plasma big endothelin-1, plasma endothelin-1 and serum soluble e-selectin concentrations were significantly elevated after two hours at -18 degrees C (p < 0.05, p < 0.05 and p < 0.01 respectively). At +4 degrees C, plasma big endothelin-1 and endothelin-1 concentrations rose significantly after 5 hours (p < 0.005 for both) but not after 2.5 hours. Low altitude mountaineering did not alter circulating marker concentrations. At high altitude, big endothelin-1 and endothelin-1 (p < 0.01 for both) rose significantly at 2500 m and initially at 5000 m but returned to sea level values after prolonged exposure to 5000 m. Serum e-selectin rose at all altitudes greater than sea level (p < 0.05). In conclusion, exposure to high altitude, moderate cold or freezing temperatures, but not exercise, selectively activates endothelial cells increasing endothelin-1 production. Cold exposure may contribute to the observed increase in plasma endothelin-1 in mountaineers at high altitude. 相似文献
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McCarroll JE Newby JH Thayer LE Norwood AE Fullerton CS Ursano RJ 《Military medicine》1999,164(2):77-84
OBJECTIVE: To report the distributions and characteristics of spouse abuse victims and offenders in the U.S. Army Central Registry from 1989 to 1997. METHOD: Case and population data were tabulated using SAS procedures. RESULTS: There were 61,827 initial substantiated cases, 5,772 subsequent incidents, and 3,921 reopened cases. Victim rates varied between 8 and 10.5 per 1,000 married persons. About 82% of victims and offenders were between the ages of 18 and 31 years. The racial distribution of married active duty white and black victims and offenders was greatly different from that of the married active duty population. The proportion of female victims increased from initial (67%) to subsequent (71%) to reopened cases (75%). CONCLUSIONS: U.S. military populations provide unique opportunities to study family violence because of the socioeconomic "floor" under service members and their families. Comparisons between military and civil populations on precipitating circumstances, case assessment and definition, and treatment efficacy would be fruitful areas for research. 相似文献