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排序方式: 共有882条查询结果,搜索用时 15 毫秒
1.
Alexandra Katsimardou Konstantinos Imprialos Konstantinos Stavropoulos Alexandros Sachinidis Michalis Doumas 《Expert opinion on pharmacotherapy》2020,21(10):1241-1252
ABSTRACT
Introduction
Type 1 diabetes mellitus (T1DM) is a chronic, autoimmune disease that is characterized by total absence of insulin production. Hypertension is a common comorbidity in T1DM with complex pathophysiology, while it is also a well-recognized risk factor for the development of cardiovascular disease (CVD), as well as other microvascular diabetic complications. 相似文献2.
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Using linear and non-linear methods, electroencephalographic (EEG) signals were measured at various brain regions to provide information regarding patterns of local and coordinated activity during performance of three arithmetic tasks (number comparison, single-digit multiplication, and two-digit multiplication) and two control tasks that did not require arithmetic operations. It was hypothesized that these measures would reveal the engagement of local and increasingly complex cortical networks as a function of task specificity and complexity. Results indicated regionally increased neuronal signalling as a function of task complexity at frontal, temporal and parietal brain regions, although more robust task-related changes in EEG-indices of activation were derived over the left hemisphere. Both linear and non-linear indices of synchronization among EEG signals recorded from over different brain regions were consistent with the notion of more "local" processing for the number comparison task. Conversely, multiplication tasks were associated with a widespread pattern of distant signal synchronizations, which could potentially indicate increased demands for neural networks cooperation during performance of tasks that involve a greater number of cognitive operations. 相似文献
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Tolis GA Michalis A Pouliou A Ivros C Bolos C Sfyras N 《Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital》1986,13(3):337-339
The following case report describes an early complication of a Carpentier-Edwards porcine heterograft in the mitral position that required emergency replacement of the malfunctioning biological prosthesis with a mechanical one. The leaflets of the valve were in a fixed-open position and would not unfold with left ventricular contractions, resulting in severe mitral regurgitation. After failure to mobilize the valve leaflets, the porcine heterograft valve was excised intact and replaced with a 27 mm Bj?rk-Shiley monostrut prosthesis. The patient was discharged 18 days after operation on Digoxin 0.25 mg daily, Lasix 40 mg twice a week, and Sintrom 2 mg daily. He remains in excellent condition 20 months postoperatively. 相似文献
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Makedos G Papanicolaou A Hitoglou A Kalogiannidis I Makedos A Vrazioti V Goutzioulis M 《Archives of gynecology and obstetrics》2007,275(2):121-124
Objective Elevated plasma homocysteine has been implicated in vascular changes compatible with atherosis and endothelial dysfunction
similar to the vascular changes of the placenta in preeclampsia. Previous reports have indicated an increased incidence of
hyperohomocysteinemia in preeclamptic patients. The aim of this study was to examine the association of homocysteine levels
and preeclampsia in our patients.
Study design Prospective study of 28 preeclamptic patients that were matched with 26 normal controls of the same gestational age.
Results The preeclamptic group had an increased incidence of cesarean sections (75%), of growth retarded fetuses (50%), intrauterine
deaths (7%) and placental abruptions (7%). Mean levels of homocysteine were significantly elevated in the preeclamptic than
in control group (11.11 vs. 6.40 μmol/l, P < 0.001). There were no differences between the groups regarding the levels of folic acid (11.12 vs. 9.73 ng/ml, P = 0.55) and vitamin B12 (295.76 vs. 356.15 pg/ml, P = 0.43).
Conclusion It is concluded that in our study homocysteine levels are significantly elevated in patients with preeclampsia compared with
control group, while no vitamin deficiencies were observed. 相似文献
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This study tested a brief, Web-based personalized feedback program aimed at reducing alcohol use and alcohol-related consequences among 9th grade students (N = 513). Results indicated no differences between the control group and intervention group on either frequency of drinking or alcohol-related consequences at the 6-month follow-up. Reductions in alcohol use and the associated consequences found at the 3-month follow-up were not sustained across the academic year. Results indicate that brief, Web-based feedback programs may not be sufficient to provide a sustained impact on alcohol use and alcohol-related consequences over time, suggesting either booster sessions or adjunctive interventions, such as parent-based interventions, may be warranted for this age group. 相似文献