全文获取类型
收费全文 | 19651篇 |
免费 | 944篇 |
国内免费 | 122篇 |
专业分类
耳鼻咽喉 | 176篇 |
儿科学 | 302篇 |
妇产科学 | 184篇 |
基础医学 | 2278篇 |
口腔科学 | 438篇 |
临床医学 | 1234篇 |
内科学 | 4928篇 |
皮肤病学 | 1145篇 |
神经病学 | 1858篇 |
特种医学 | 758篇 |
外科学 | 3294篇 |
综合类 | 121篇 |
预防医学 | 486篇 |
眼科学 | 163篇 |
药学 | 1643篇 |
中国医学 | 43篇 |
肿瘤学 | 1666篇 |
出版年
2023年 | 95篇 |
2022年 | 141篇 |
2021年 | 386篇 |
2020年 | 204篇 |
2019年 | 259篇 |
2018年 | 386篇 |
2017年 | 290篇 |
2016年 | 356篇 |
2015年 | 389篇 |
2014年 | 500篇 |
2013年 | 562篇 |
2012年 | 876篇 |
2011年 | 975篇 |
2010年 | 539篇 |
2009年 | 450篇 |
2008年 | 887篇 |
2007年 | 957篇 |
2006年 | 920篇 |
2005年 | 861篇 |
2004年 | 950篇 |
2003年 | 912篇 |
2002年 | 899篇 |
2001年 | 614篇 |
2000年 | 683篇 |
1999年 | 644篇 |
1998年 | 286篇 |
1997年 | 216篇 |
1996年 | 199篇 |
1995年 | 178篇 |
1994年 | 159篇 |
1993年 | 123篇 |
1992年 | 462篇 |
1991年 | 405篇 |
1990年 | 414篇 |
1989年 | 434篇 |
1988年 | 412篇 |
1987年 | 380篇 |
1986年 | 327篇 |
1985年 | 292篇 |
1984年 | 171篇 |
1983年 | 156篇 |
1982年 | 88篇 |
1979年 | 167篇 |
1978年 | 83篇 |
1977年 | 88篇 |
1974年 | 72篇 |
1973年 | 82篇 |
1972年 | 85篇 |
1970年 | 74篇 |
1969年 | 69篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
Shingo Hashimoto Masaki Katsurada Rie Muramatsu Kumiko Asai Kenichiro Tanaka Kensuke Hayashi Yoshiaki Kibe Koichiro Nakajima Yukiko Hattori Hiromitsu Iwata Jun-etsu Mizoe Hiroyuki Ogino Yuta Shibamoto 《Practical radiation oncology》2019,9(2):e149-e155
Purpose
Suppression of respiratory movement of the liver would be desirable for high-precision radiation therapy for liver tumors. We aimed to investigate the effect of our original device-free compressed shell fixation method and breathing instruction on suppression of respiratory movement. The characteristics of liver motion based on the movement of a fiducial marker were also analyzed.Methods and Materials
First, respiratory amplitudes of the liver with the device-free compressed shell were analyzed from the data of 146 patients. The effect of this shell fixing method on liver movement was evaluated. Second, as another cohort study with 166 patients, interfractional internal motion of the liver for patients fixed in the shell was calculated using the fiducial marker coordinate data of images for position setting before daily irradiation. Third, in another 12 patients, intrafractional internal motion was calculated from the fiducial marker coordinate data using x-ray images before and after irradiation.Results
The median respiratory movement without the shell, after fixing with the shell, and after instructing on the breathing method with the shell was 14.2 (interquartile range, 10.7-19.8), 11.5 (8.6-17.5), and 10.4 mm (7.3-15.8), respectively. Systematic and random errors of interfractional internal motion were all ≤2 mm in the left-right and anteroposterior directions and 3.7 and 3.0 mm, respectively, in the craniocaudal direction. Systematic and random errors of intrafractional internal motion were all ≤1.3 mm in the left-right and anteroposterior directions and 0.8 and 2.4 mm, respectively, in the craniocaudal direction.Conclusions
The device-free compressed shell fixation method was effective in suppressing the respiratory movement of the liver. Irradiation position matching using the fiducial marker can correct the interfractional internal motion on each day, which would contribute to the reduction of the margin to be given around the target. 相似文献3.
A case of bullous pemphigoid associated with psoriasis vulgaris showing Hailey–Hailey disease‐like histopathological changes in regenerated epidermis without genomic mutation in ATP2C1 or ATP2A2 gene
下载免费PDF全文
![点击此处可从《Journal of the European Academy of Dermatology and Venereology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
4.
5.
Hiroto Kinoshita Hitomi Nishioka Aya Ikeda Kyoko Ikoma Yoichi Sameshima Hidehisa Ohi Mizuki Tatsuno Junka Kouyama Chiaki Kawamoto Tomohiro Mitsui Yuko Tamura Yu Hashimoto Masashi Nishio Tsuyoshi Ogashiwa Yusuke Saigusa Shin Maeda Hideaki Kimura Reiko Kunisaki Kazuhiko Koike 《Journal of gastroenterology and hepatology》2019,34(11):1929-1939
6.
neurogenetics - Mediator (MED) is a key regulator of protein-coding gene expression, and mutations in MED subunits are associated with a broad spectrum of diseases. Because mutations in MED17... 相似文献
7.
Mitsuhiro Tozaki Kunihiko Fukuda Masafumi Suzuki 《Magnetic resonance in medical sciences》2006,5(3):137-146
PURPOSE: The purpose of this study was to assess the relationship between the amount of scirrhous component in invasive ductal carcinoma and its MR characteristics. MATERIALS AND METHODS: We retrospectively reviewed 71 consecutive patients with invasive ductal carcinoma smaller than 25 mm (average, 16.6 mm) in diameter. The scirrhous component was defined as invasive foci in small clusters of cancer cells showing desmoplasia. Invasive ductal carcinoma was subclassified into 3 groups in accordance with the amount of the scirrhous component (scirrhous component degree; SCD): SCD I (scirrhous component less than 20%), SCD II (intermediate), and SCD III (more than 80%). Dynamic magnetic resonance (MR) imaging was performed using volumetric interpolated sequence. Prior to dynamic study, T2*-weighted first-pass perfusion images were obtained before, during, and after bolus injection of 0.1 mmol Gd-DTPA/kg. RESULTS: Twenty-eight lesions were classified as SCD I, 14 as SCD II, and 29 as SCD III. Mass margin and signal intensity loss in the perfusion study were significantly different among the 3 SCD groups (P<0.001). The kinetic patterns were significantly different among the 3 SCD groups (P=0.04), and between SCD I/II and SCD III (P=0.03). The presence of enhancing internal septations was significantly different between SCD I/II and SCD III carcinomas (P=0.05). Central enhancement was only observed in SCD I carcinoma (4%; 3/71). CONCLUSION: The histological predominance of the scirrhous component in invasive ductal carcinoma may be one explanation for the differences in morphologic and kinetic patterns on MR imaging. 相似文献
8.
Kengo Maeda Shinji Kume Yoshihiko Nishio Shiro Maeda Yasuhiro Nishida Mikio Suzuki Takahiro Nakaguchi Toru Kawabata Osamu Hashimoto Takashi Hisanaga Atsunori Kashiwagi Hitoshi Yasuda 《Clinical neurology》2006,46(4):266-269
We report a 53-year-old woman with severe Graves' ophthalmopathy accompanied by uncontrolled myasthenia gravis. She presented remarkable exophthalmos, chemosis, and restriction of eye movement. Despite plasma exchange, steroid pulse therapy, local injection of steroid, and irradiation, ocular symptoms did not ameliorate. Since optic neuropathy was seen, orbital decompression surgery was performed in the left eye. Bilateral chemosis was improved after the surgery. Five years after surgery, there was no ocular palsy in the operated left eye, but in the contralateral eye. For the good prognosis of the eye movement, orbital decompression might be recommended in the severe Graves' ophthalmopathy accompanied by the optic neuropathy and/or ophthalmoplegia with proptosis. 相似文献
9.
10.
M Yoshino Y Sakaguchi N Kuriya Y Ohtani F Yamashita T Hashimoto K Oyanagi K Tada K Narisawa T Kitagawa 《Neuropediatrics》1991,22(4):198-202
A nationwide survey of transient hyperammonemia in newborns was carried out in Japan. A total of 18 patients, consisting of 12 male and 6 female infants, were reported from 11 facilities. These neonates exhibited hyperammonemia with plasma ammonia levels in the range from 124 to 6256 micrograms/dl. Four newborn infants of the 18 died in the neonatal period, and an additional one died in the early infancy. Among the 13 infants who were alive at the time of this survey, 6 had neurological sequelae, including mental retardation, spastic quadriplegia and epilepsy. The multivariate analysis revealed that the Apgar score at 1 minute, peak plasma ammonia concentration, birth weight and sex were significant factors affecting the prognosis of life. 相似文献