全文获取类型
收费全文 | 1338篇 |
免费 | 87篇 |
国内免费 | 1篇 |
专业分类
耳鼻咽喉 | 7篇 |
儿科学 | 101篇 |
妇产科学 | 24篇 |
基础医学 | 179篇 |
口腔科学 | 10篇 |
临床医学 | 166篇 |
内科学 | 239篇 |
皮肤病学 | 17篇 |
神经病学 | 153篇 |
特种医学 | 47篇 |
外国民族医学 | 1篇 |
外科学 | 120篇 |
综合类 | 8篇 |
一般理论 | 2篇 |
预防医学 | 172篇 |
眼科学 | 32篇 |
药学 | 59篇 |
中国医学 | 1篇 |
肿瘤学 | 88篇 |
出版年
2023年 | 13篇 |
2022年 | 11篇 |
2021年 | 26篇 |
2020年 | 15篇 |
2019年 | 16篇 |
2018年 | 33篇 |
2017年 | 27篇 |
2016年 | 21篇 |
2015年 | 30篇 |
2014年 | 31篇 |
2013年 | 55篇 |
2012年 | 91篇 |
2011年 | 82篇 |
2010年 | 42篇 |
2009年 | 53篇 |
2008年 | 65篇 |
2007年 | 76篇 |
2006年 | 58篇 |
2005年 | 73篇 |
2004年 | 61篇 |
2003年 | 56篇 |
2002年 | 71篇 |
2001年 | 24篇 |
2000年 | 20篇 |
1999年 | 28篇 |
1998年 | 18篇 |
1997年 | 13篇 |
1996年 | 8篇 |
1995年 | 7篇 |
1994年 | 6篇 |
1993年 | 17篇 |
1992年 | 20篇 |
1991年 | 24篇 |
1990年 | 15篇 |
1989年 | 15篇 |
1988年 | 20篇 |
1987年 | 15篇 |
1986年 | 13篇 |
1985年 | 13篇 |
1984年 | 17篇 |
1983年 | 11篇 |
1982年 | 12篇 |
1981年 | 6篇 |
1980年 | 11篇 |
1976年 | 7篇 |
1975年 | 7篇 |
1974年 | 9篇 |
1973年 | 6篇 |
1972年 | 6篇 |
1971年 | 7篇 |
排序方式: 共有1426条查询结果,搜索用时 78 毫秒
1.
2.
High-resolution myocardial perfusion mapping in small animals in vivo by spin-labeling gradient-echo imaging. 总被引:1,自引:0,他引:1
Frank Kober Isabelle Iltis Marguerite Izquierdo Martine Desrois Danielle Ibarrola Patrick J Cozzone Monique Bernard 《Magnetic resonance in medicine》2004,51(1):62-67
An ECG and respiration-gated spin-labeling gradient-echo imaging technique is proposed for the quantitative and completely noninvasive measurement and mapping of myocardial perfusion in small animals in vivo. In contrast to snapshot FLASH imaging, the spatial resolution of the perfusion maps is not limited by the heart rate. A significant improvement in image quality is achieved by synchronizing the inversion pulse to the respiration movements of the animals, thereby allowing for spontaneous respiration. High-resolution myocardial perfusion maps (in-plane resolution=234 x 468 microm2) demonstrating the quality of the perfusion measurement were obtained at 4.7 T in a group of seven freely breathing Wistar-Kyoto rats under isoflurane anesthesia. The mean perfusion value (group average +/- SD) was 5.5 +/- 0.7 ml g(-1)min(-1). In four animals, myocardial perfusion was mapped and measured under cardiac dobutamine stress. Perfusion increased to 11.1 +/- 1.9 ml g(-1)min(-1). The proposed method is particularly useful for the study of small rodents at high fields. 相似文献
3.
4.
5.
E Dobremez Y Lefevre L Harper L Rebouissoux F Lavrand J M Bondonny P Vergnes 《Zeitschrift für Kinderchirurgie》2006,16(3):166-170
AIM: Conservative management of splenic rupture in haemodynamically stable children is now generally accepted. However, during follow-up, many complications can occur. The aim of this study was to describe the complications we observed and to propose a standardised follow-up adapted to them. METHODS: Between March 1992 and December 2002 we managed 65 children (aged between 3 and 15 years old) with accidental splenic rupture. Follow-up and treatment consisted of a 10-day bed rest with sonogram and Doppler controls on the 5th and 10th day and subsequently every month until complete healing. Complications included secondary haemorrhage in 3 cases, cystic evolution in 5 cases, and pseudo-aneurysm in 2 cases. All were treated by renewed bed rest. Three of the cysts resolved spontaneously, the other two underwent cystic resection and epiploplasty by laparotomy (n = 1) or laparoscopy (n = 1) and both pseudo-aneurysms were selectively embolised. There were no splenectomies. CONCLUSIONS: Complications essentially occurred in older children and were not related to gender, type of fracture, or extent of bleeding. Cystic evolution of the sub-capsular haematomas can appear up to 1 month after trauma. Peripheral pseudo-aneurysms which could be responsible for secondary haemorrhages were selectively embolised. We favour the use of the Doppler sonogram for follow-up until total recovery of these patients, even in low-grade traumas. Considering the number of complications encountered we do not believe the American evidence-based guidelines are suitable for our population. 相似文献
6.
7.
Marguerite J. DNP RN Vallire D. MSN RN CPAN FAAN Ellen BSN RN CPAN Theresa MSN RN CPAN Christian C. MD PhD 《Journal of PeriAnesthesia Nursing》2006,21(6):377-384
Postoperative nausea and vomiting (PONV) is a common and potentially debilitating complication of surgery. The preoperative assessment of PONV using established risk assessment tools enables the identification of patients at risk and potentially decreases the incidence of PONV in adult surgical patients. The identification of risk factors associated with PONV and the factors that are independent predictors of PONV preoperatively can facilitate the effective prophylactic treatment and management of PONV in adult surgical patients. 相似文献
8.
M Vergnes 《Physiology & behavior》1976,17(3):439-444
The effect of lateral amygdala or stria terminalis lesions on two different kinds of aggressive behavior have been studied in the rat. The lateral amygdala lesion does not change the non-killing rat's behavior towards mice; but it markedly reduces the shock-induced intraspecific aggression, without changing the flinch and jump thresholds to the electric shocks. A bilateral interruption of the stria terminalis elicits aggressive reactions in previously non killing rats. This initiation of mouse killing behavior is clearly facilitated through a prior food deprivation for 3 days. The interruption of the stria terminalis changes neither the shock induced aggression, nor the response thresholds. As the stria is the main efferent pathway of the cortico-medial nuclei of the amygdala, these results are in accordance with previous conclusions that tentatively localized in this part of the amygdala an essential component of a mechanism which inhibits muricide behavior in the non killing rat, probably through interactions with the olfactory input. This system is largely independent of amygdaloid structures which facilitate shock-induced intraspecific aggression. 相似文献
9.
M Vergnes 《Physiology & behavior》1975,14(3):271-276
Long-Evans hooded rats were tested for emotionality and observed by pairs in an open field for 6 consecutive days. Postoperative observations indicated that both emotionality and social cohesiveness were dramatically altered by ventromedial and anterolateral hypothalamic lesions. Tegmental, interpeduncular and habenular lesions were shown to have no effect on these behaviors. Alterations in behavior observed following hypothalamic ablations were related to septal and amygdaloid effects, and the possibility of separate projection systems for emotionality and social cohesiveness was discussed. 相似文献
10.
Emergence of rifampin-resistant Rhodococcus equi with several types of mutations in the rpoB gene among AIDS patients in northern Thailand
下载免费PDF全文
![点击此处可从《Journal of clinical microbiology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Asoh N Watanabe H Fines-Guyon M Watanabe K Oishi K Kositsakulchai W Sanchai T Kunsuikmengrai K Kahintapong S Khantawa B Tharavichitkul P Sirisanthana T Nagatake T 《Journal of clinical microbiology》2003,41(6):2337-2340
The antimicrobial susceptibilities of 30 Rhodococcus equi isolates obtained from 30 patients between 1993 and 2001 in northern Thailand were investigated. The MICs showed a tendency toward resistance to various antibiotics but sensitivity to imipenem, minocycline, vancomycin, and teicoplanin (MICs, =0.5 micro g/ml) and relative sensitivity to meropenem, clarithromycin, and ciprofloxacin (MICs, =2 micro g/ml). Of the 30 isolates, 26 were susceptible (MICs, =1 micro g/ml), 1 showed low-level resistance (MIC, 8 micro g/ml), and 3 showed high-level resistance (MICs, >/=64 micro g/ml) to rifampin. PCR amplification and DNA sequencing of the rpoB gene and molecular typing by pulsed-field gel electrophoresis (PFGE) were performed for eight R. equi isolates from eight AIDS patients with pneumonia or lung abscess caused by R. equi between 1998 and 2001, including one low- and three high-level rifampin-resistant isolates. As a result, two high-level rifampin-resistant strains with PFGE pattern A had a Ser531Trp (Escherichia coli numbering) mutation, and one high-level rifampin-resistant strain with PFGE pattern B had a His526Tyr mutation, whereas one low-level rifampin-resistant strain with PFGE pattern C had a Ser509Pro mutation. Four rifampin-susceptible strains with PFGE patterns D and E showed an absence of mutation in the rpoB region. Our results indicate the presence of several types of rifampin-resistant R. equi strains among AIDS patients in northern Thailand. 相似文献