全文获取类型
收费全文 | 15251篇 |
免费 | 1102篇 |
国内免费 | 74篇 |
专业分类
耳鼻咽喉 | 144篇 |
儿科学 | 318篇 |
妇产科学 | 269篇 |
基础医学 | 2360篇 |
口腔科学 | 121篇 |
临床医学 | 1930篇 |
内科学 | 3729篇 |
皮肤病学 | 281篇 |
神经病学 | 1373篇 |
特种医学 | 621篇 |
外国民族医学 | 3篇 |
外科学 | 2266篇 |
综合类 | 51篇 |
一般理论 | 7篇 |
预防医学 | 764篇 |
眼科学 | 281篇 |
药学 | 933篇 |
中国医学 | 23篇 |
肿瘤学 | 953篇 |
出版年
2023年 | 98篇 |
2022年 | 128篇 |
2021年 | 443篇 |
2020年 | 238篇 |
2019年 | 370篇 |
2018年 | 428篇 |
2017年 | 298篇 |
2016年 | 332篇 |
2015年 | 402篇 |
2014年 | 534篇 |
2013年 | 692篇 |
2012年 | 1128篇 |
2011年 | 1222篇 |
2010年 | 622篇 |
2009年 | 598篇 |
2008年 | 945篇 |
2007年 | 927篇 |
2006年 | 927篇 |
2005年 | 888篇 |
2004年 | 822篇 |
2003年 | 749篇 |
2002年 | 701篇 |
2001年 | 243篇 |
2000年 | 231篇 |
1999年 | 215篇 |
1998年 | 161篇 |
1997年 | 136篇 |
1996年 | 100篇 |
1995年 | 79篇 |
1994年 | 68篇 |
1993年 | 76篇 |
1992年 | 139篇 |
1991年 | 125篇 |
1990年 | 112篇 |
1989年 | 138篇 |
1988年 | 111篇 |
1987年 | 104篇 |
1986年 | 97篇 |
1985年 | 84篇 |
1984年 | 78篇 |
1983年 | 57篇 |
1982年 | 35篇 |
1981年 | 32篇 |
1980年 | 40篇 |
1979年 | 51篇 |
1978年 | 33篇 |
1975年 | 45篇 |
1974年 | 31篇 |
1973年 | 33篇 |
1967年 | 30篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
Timo Rath Lukas Pfeifer Clemens Neufert reas Kremer Moritz Leppkes Arthur Hoffman Markus F Neurath Steffen Zopf 《World journal of gastroenterology : WJG》2020,26(16):1962-1970
BACKGROUND The adenoma detection rate(ADR) is inversely associated with the incidence of interval colorectal cancer and serves as a benchmark quality criterion during screening colonoscopy. However, adenoma miss rates reach up to 26% and studies have shown that a second inspection of the right colon in retroflected view(RFV) can increase ADR.AIM To assess whether inspection of the whole colon in RFV compared to standard forward view(SFV) can increase ADR.METHODS Patients presenting for screening or surveillance colonoscopy were invited to participate in this randomized controlled trial and randomized into two arms. In RFV arm colonoscopy was initially performed with SFV, followed by a second inspection of the whole colon in RFV. In the SFV arm first withdrawal was performed with SFV, followed by a second inspection of the whole colon again with SFV. Number, size and morphology of polyps found during first and second inspection in each colonic segment were recorded and all polyps were removed and sent for histopathology in separate containers.RESULTS Two hundred and five patients were randomly assigned to the RFV(n = 101) and SFV(n = 104) arm. In the RFV arm, both polyp detection rate(PDR) and ADR were increased under second inspection in RFV(PDR 1~(st) SFV: 39.8%, PDR 2~(nd)RFV: 46.6%; ADR 1~(st) SFV: 35.2%, ADR 2~(nd) RFV: 42%). Likewise, in the SFV arm,PDR and ADR were increased under second inspection(PDR 1~(st) SFV: 37.5%, PDR 2~(nd) SFV: 46.6%; ADR 1~(st) SFV: 34.1%, ADR 2~(nd)SFV: 44.3%) with no significant differences in ADR and PDR between the SFV and RFV arm. Mean number of adenomas per patient(APP) was increased in the RFV and SFV(APP RFV arm: 1~(st) SFV: 1.71; 2~(nd) RFV: 2.38; APP SFV arm: 1~(st) SFV: 1.83, 2~(nd)SFV:2.2). The majority of adenomas additionally found during second inspection in RFV or in SFV were located in the transverse and left-sided colon and were 5 mm in size.CONCLUSION Second inspection of the whole colon leads to increased adenoma detection with no differences between SFV and RFV. Hence, increased detection is most likely a feature of the second inspection itself but not of the inspection mode. 相似文献
2.
Matthieu Talagas Nicolas Lebonvallet Franois Berthod Laurent Misery 《Experimental dermatology》2019,28(12):1466-1469
Recent years have brought an enhanced understanding of keratinocyte contribution to cutaneous nociception. While intra‐epidermal nerve endings were classically considered as the exclusive transducers of cutaneous noxious stimuli, it has now been demonstrated that epidermal keratinocytes can initiate nociceptive responses, like Merkel cells do for the innocuous mechanotransduction. In the light of recent in vivo findings, this article outlines this paradigm shift that points to a not yet considered population of sensory epidermal cells. 相似文献
3.
4.
5.
Laurent Boyer Patrice Francois Elisabeth Doutre Georges Weil Jose Labarere 《International journal for quality in health care》2006,18(5):359-364
OBJECTIVE: . The aim of this study was to assess clinical staff's opinions on the results of in-patient satisfaction surveys and their use within the quality improvement process. SETTING: The institution is a 2200-bed teaching hospital of tertiary health care employing 8000 professionals. Patient satisfaction surveys are carried out each year using a validated questionnaire mailed to a random sample of patients. The specific results of each department are sent to the medical and paramedical managers. METHODS: We conducted a questionnaire survey on 500 care providers randomly selected in every medical and surgical department. RESULTS: A total of 261 questionnaires were returned and analysed. Overall, 94% of responders had a favourable opinion of the patient satisfaction surveys. They considered that the patient was able to judge hospital service quality, especially in its relational, organizational, and environmental dimensions. The specific results for the department were less well known than the overall hospital results (60 versus 76%). These results were formally discussed in the department according to 40% of responders; 40% declared that these data resulted in improvement actions and considered that they led to modifications in their behaviour with patients. CONCLUSIONS: Despite a declared interest in satisfaction surveys, the results remain underused by hospital staff and insufficiently discussed within teams. 相似文献
6.
7.
Laurent Brochard 《Critical care (London, England)》2006,10(4):156
The pressure–volume (PV) curve is a physiological tool proposed for diagnostic or monitoring purposes during mechanical ventilation of acute respiratory distress syndrome. The reduction in compliance measured by the PV curve and the different inflection points on the curve are considered interesting markers of the severity of and the levels of opening and closing pressures. Tracing a curve, however, may in itself influence the degree of opening or distension of the lung, and interpretation of the curve has to take this effect into account. In some individuals tracing the curve may even have moderate hemodynamic effects. Fortunately, on average, most of these effects are transient or negligible and do not invalidate the PV curve measurement. 相似文献
8.
9.
Denis Mariano-Goulart Laurent Déchaux Fran?ois Rouzet Eric Barbotte Charles Caderas de Kerleau Michel Rossi Dominique Le Guludec 《Journal of nuclear medicine》2007,48(9):1416-1423
This study aimed to assess the ability of global and local systolic parameters measured with gated blood-pool SPECT (GBPS) to diagnose and characterize the severity of diffuse or localized arrhythmogenic right ventricular dysplasia (ARVD). METHODS: Fifty-nine subjects with symptomatic ventricular arrhythmias were prospectively included in the study. With the International Society and Federation of Cardiology criteria for ARVD as a gold standard, these subjects were classified as subjects without ARVD (21 control subjects) and patients with localized ARVD (16 patients) or diffuse ARVD (22 patients). Right ventricular volumes, right ventricular ejection fractions (EF), the SD of local EF (sigma-EF), and the SD of the local times of end systole (sigma-TES) were computed from GBPS data and compared among the groups in the study population. RESULTS: sigma-EF did not differ between control subjects and patients with diffuse or localized ARVD. Right ventricular EF and volumes differed between patients with diffuse ARVD and control subjects, with similar areas under the receiver-operating-characteristic curves, but right ventricular EF and volumes failed to differentiate patients with localized ARVD. In contrast, sigma-TES differed between patients with diffuse or localized ARVD and control subjects. Regression analysis showed that the systolic parameter most strongly associated with the diagnosis of ARVD was sigma-TES. The probabilities of a randomly chosen patient in the diffuse ARVD group and of a randomly chosen patient in the localized ARVD group having sigma-TES values greater than that of a randomly chosen control subject were 98.5% and 96.7%, respectively. For the diagnosis of localized ARVD, a threshold of 80 ms for sigma-TES corresponded to sensitivity, specificity, and positive and negative predictive values of 100%, 81%, 80%, and 100%, respectively. CONCLUSION: With GBPS, both diffuse ARVD and localized ARVD can be accurately diagnosed by computing sigma-TES for all of the pixels on the surface of the right ventricle. 相似文献
10.