全文获取类型
收费全文 | 2075篇 |
免费 | 117篇 |
国内免费 | 59篇 |
专业分类
耳鼻咽喉 | 5篇 |
儿科学 | 214篇 |
妇产科学 | 40篇 |
基础医学 | 190篇 |
口腔科学 | 27篇 |
临床医学 | 214篇 |
内科学 | 361篇 |
皮肤病学 | 51篇 |
神经病学 | 73篇 |
特种医学 | 323篇 |
外科学 | 284篇 |
综合类 | 25篇 |
预防医学 | 91篇 |
眼科学 | 5篇 |
药学 | 193篇 |
中国医学 | 2篇 |
肿瘤学 | 153篇 |
出版年
2023年 | 7篇 |
2022年 | 8篇 |
2021年 | 16篇 |
2020年 | 15篇 |
2019年 | 21篇 |
2018年 | 31篇 |
2017年 | 11篇 |
2016年 | 18篇 |
2015年 | 26篇 |
2014年 | 34篇 |
2013年 | 63篇 |
2012年 | 70篇 |
2011年 | 63篇 |
2010年 | 65篇 |
2009年 | 80篇 |
2008年 | 62篇 |
2007年 | 103篇 |
2006年 | 56篇 |
2005年 | 73篇 |
2004年 | 55篇 |
2003年 | 42篇 |
2002年 | 41篇 |
2001年 | 47篇 |
2000年 | 51篇 |
1999年 | 54篇 |
1998年 | 84篇 |
1997年 | 91篇 |
1996年 | 114篇 |
1995年 | 67篇 |
1994年 | 70篇 |
1993年 | 62篇 |
1992年 | 36篇 |
1991年 | 43篇 |
1990年 | 41篇 |
1989年 | 55篇 |
1988年 | 65篇 |
1987年 | 60篇 |
1986年 | 65篇 |
1985年 | 60篇 |
1984年 | 28篇 |
1983年 | 24篇 |
1982年 | 25篇 |
1981年 | 17篇 |
1980年 | 17篇 |
1979年 | 16篇 |
1978年 | 21篇 |
1977年 | 16篇 |
1976年 | 20篇 |
1975年 | 18篇 |
1972年 | 6篇 |
排序方式: 共有2251条查询结果,搜索用时 15 毫秒
1.
2.
3.
JC Sitek† M Loeb‡ JR Ronnevig¶ 《Journal of the European Academy of Dermatology and Venereology》2007,21(7):891-896
BACKGROUND: Since 1997, a number of trials have shown promising results in treating generalized vitiligo with narrowband ultraviolet B (UVB) both in adults and children. However, there is little knowledge concerning the duration and permanency of the treatment-induced repigmentation. OBJECTIVE: Our main objective was to perform a follow-up trial of successfully treated patients receiving narrowband UVB for generalized vitiligo. METHODS: We have investigated to what degree the treatment-induced repigmentation remains stable for up to 2 years post-treatment. We performed an initial open trial including 31 patients with generalized vitiligo. They received narrowband UVB thrice weekly for up to 12 months. Patients experiencing > 75% repigmentation were defined responders and were included in the follow-up trial. Responders were followed every 6 months for up to 2 years after cessation of treatment. We observed the pigmentation status and registered any changes indicating loss of pigmentation and relapse. RESULTS: Eleven of the 31 treated patients were included in the follow-up trial. Six patients had relapse and five patients had stable response 24 months after cessation of treatment. Four out of six relapses were within 6 months post-treatment. CONCLUSION: In our study population of 31 patients with generalized vitiligo, five patients (16%) experienced > 75% stable repigmentation 2 years after cessation of a treatment programme of up to 1 years narrowband UVB therapy. 相似文献
4.
A modified labioplasty to improve the cosmetic appearance after feminizing genitoplasty is described. Good results were obtained in all five patients in whom the technique was utilized. 相似文献
5.
Pernes JM; Vitoux JF; Brenoit P; Raynaud A; Parola JL; Roth JP; Angel CY; Fiessinger JN; Roncato M; Gaux JC 《Radiology》1986,158(2):481-485
Thirty-five patients hospitalized for recent angiographically documented arterial occlusion in the legs (27 femoropopliteal arteries and eight grafts) benefited from local fibrinolytic therapy delivered at the site of the occlusion with a 4- or 5-F catheter. This therapy combined a continuous urokinase (UK) infusion of 1,000 U/kg/hour and a lysyl plasminogen (LYS-PLG) infusion of 15 microkatals every 30 minutes. Angiographically confirmed lysis was obtained in 85% of the cases. Only 3% of the patients had major and 6% had minor groin hematomas. Only two patients had concentrations of fibrinogen as low as 100 mg/dl. Intravascular infusion of UK-LYS-PLG is as effective as streptokinase. Its excellent tolerance makes it a good alternative in the treatment of acute ischemia in the lower limbs. 相似文献
6.
Ultrasound (US) can be used to visualize vertebral segments, suggesting a quantitative means of studying vertebral column growth in utero and thus a means of detecting developmental abnormalities. US images of the lumbar spine were obtained in 128 clinically normal fetuses between the gestational age of 11 through 41 weeks. A large-aperture, dynamically focused US system capable of regional magnification was used. Average lumbar spacing was calculated from distance between centrums of at least four lumbar bodies. The average distance between lumbar centrums increased nearly linearly throughout the second and third trimesters (r2 = 0.98). Enhanced anatomic display implies new capabilities for recognizing developmental abnormalities antenatally. 相似文献
7.
8.
The effects of calcitonin gene-related peptide (CGRP) and CGRP 8-37 on the neonatal mouse gubernaculum were examined in organ culture, with the aim of seeing whether CGRP has a direct effect on the gubernaculum. A total of 440 gubernacula were studied. Two hundred and fifty gubernacula were treated with CGRP in concentrations ranging from 0-714 nM/liter. With increasing doses of CGRP the percentage of gubernacula showing vigorous contraction increased from 18-50%. The total percentage of gubernacula showing any form of contraction increased from 76-96%. One hundred and fifty gubernacula were exposed to the CGRP analog CGRP 8-37. Increasing concentrations of CGRP 8-37 from 179-714 nM/liter decreased the rate of vigorous contraction from 18-4%. The percentage of gubernacula showing any degree of contraction decreased from 76-14%. Forty gubernacula removed from testicular feminization (TFM) mice were exposed to varying concentrations of CGRP. In the absence of exogenous CGRP no contractility was observed. By contrast, in the presence of CGRP the gubernacula showed vigorous contractility increasing from 38-90%. The total number of gubernacula showing contraction increased from 75-100%. These studies demonstrated that the neonatal mouse gubernaculum exhibits a high level of endogenous contractility, which can be enhanced in a dose responsive manner with exogenous CGRP. CGRP 8-37 caused a dose responsive inhibition. The androgen-insensitive gubernaculum from the TFM mouse showed no endogenous contraction, but on exposure to CGRP showed an enhanced rate of contractility. These results are consistent with the hypothesis that androgens may control gubernacular migration indirectly via release of CGRP from the genitofemoral nerve in the inguinoscrotal region. The failure of gubernacular motility in vitro and migration in vivo in the TFM mouse may indicate lack of CGRP release from the genitofemoral nerve. 相似文献
9.
LN Weinberger MJ Zirwas JC English III 《Journal of the European Academy of Dermatology and Venereology》2007,21(2):156-162
Male genital oedema can be defined as swelling or the appearance of swelling of the scrotum and/or the penile shaft and prepuce. Despite the various causes of genital oedema reported in the published work, a concise approach to the evaluation and management has not been sufficiently addressed. 相似文献
10.