全文获取类型
收费全文 | 2906篇 |
免费 | 361篇 |
国内免费 | 19篇 |
专业分类
耳鼻咽喉 | 15篇 |
儿科学 | 136篇 |
妇产科学 | 38篇 |
基础医学 | 422篇 |
口腔科学 | 74篇 |
临床医学 | 334篇 |
内科学 | 575篇 |
皮肤病学 | 94篇 |
神经病学 | 136篇 |
特种医学 | 305篇 |
外科学 | 302篇 |
综合类 | 103篇 |
一般理论 | 2篇 |
预防医学 | 302篇 |
眼科学 | 28篇 |
药学 | 222篇 |
1篇 | |
中国医学 | 2篇 |
肿瘤学 | 195篇 |
出版年
2021年 | 43篇 |
2020年 | 34篇 |
2019年 | 37篇 |
2018年 | 44篇 |
2017年 | 25篇 |
2016年 | 31篇 |
2015年 | 46篇 |
2014年 | 64篇 |
2013年 | 98篇 |
2012年 | 104篇 |
2011年 | 110篇 |
2010年 | 90篇 |
2009年 | 82篇 |
2008年 | 116篇 |
2007年 | 123篇 |
2006年 | 117篇 |
2005年 | 110篇 |
2004年 | 103篇 |
2003年 | 97篇 |
2002年 | 88篇 |
2001年 | 72篇 |
2000年 | 71篇 |
1999年 | 80篇 |
1998年 | 102篇 |
1997年 | 100篇 |
1996年 | 94篇 |
1995年 | 69篇 |
1994年 | 58篇 |
1993年 | 65篇 |
1992年 | 49篇 |
1991年 | 59篇 |
1990年 | 51篇 |
1989年 | 95篇 |
1988年 | 73篇 |
1987年 | 62篇 |
1986年 | 54篇 |
1985年 | 47篇 |
1984年 | 32篇 |
1983年 | 37篇 |
1982年 | 32篇 |
1980年 | 27篇 |
1979年 | 27篇 |
1978年 | 31篇 |
1977年 | 23篇 |
1976年 | 22篇 |
1975年 | 24篇 |
1973年 | 21篇 |
1972年 | 35篇 |
1969年 | 22篇 |
1968年 | 22篇 |
排序方式: 共有3286条查询结果,搜索用时 15 毫秒
1.
2.
3.
Pyomyositis: characteristics at CT and MR imaging 总被引:9,自引:0,他引:9
4.
AJ Larner MRCP 《International journal of clinical practice》1994,48(5):272-274
SUMMARY A case is reported of pseudohyperphosphataemia in association with a monoclonal gammopathy of undetermined significance. 相似文献
5.
6.
Mohamad H Yamani Daniel J Cook E Murat Tuzcu Philip Paul Norman B Ratliff Yang Yu Robert Hobbs Gustavo Rincon Corinne Bott-Silverman Nicholas Smedira James B Young Randall C Starling 《The Journal of heart and lung transplantation》2005,24(8):1014-1018
BACKGROUND: Recipients of hearts from donors with spontaneous intracerebral hemorrhage (ICH) are at increased risk of allograft vasculopathy compared with trauma donors. We have recently shown that the vitronectin receptor (integrin alpha(V)beta3) is upregulated in transplant vasculopathy. We hypothesized that donor ICH is associated with systemic activation of alpha(V)beta3 in the donor before transplantation. METHODS: We evaluated mRNA expressions of alpha(V)beta3 (TaqMan PCR) in endomyocardial biopsy samples at 1-week post-transplant in 20 recipients from ICH donors and 20 recipients from trauma donors. To investigate whether systemic activation of alpha(V)beta3 was present in the donor before transplantation, alpha(V)beta3 expression was also evaluated in the corresponding donor spleen lymphocytes. All patients underwent serial coronary intravascular ultrasound to evaluate for coronary vasculopathy. The baseline characteristics were similar except for increased donor age in the ICH Group. RESULTS: The ICH Group showed significant increased mRNA expression of alpha(V)beta3 in the heart biopsy samples (3.8-fold, p = 0.012) and in the corresponding donor spleen lymphocytes (3.5-fold, p = 0.014) compared with the Trauma Group. At 1 year, the ICH Group also showed increased progression of coronary vasculopathy. Multivariate regression analysis found that donor lymphocytic alpha(V)beta3 mRNA expression was independently associated with increased risk of vasculopathy (odds ratio, 1.9; 95% CI, 1.21-3.98, p = 0.03). CONCLUSIONS: Our report demonstrates the presence of systemic activation of alpha(V)beta3 in donors with spontaneous intracerebral hemorrhage and its association with the subsequent development of allograft vasculopathy in the recipient. 相似文献
7.
D De AJ Kanwar S Handa 《Journal of the European Academy of Dermatology and Venereology》2006,20(7):853-859
BACKGROUND: Diagnosis of atopic dermatitis (AD) depends on clinical features because no definitive diagnostic test exists. Criteria proposed by Hanifin and Rajka (Acta Derm Venereol (Stockh) 1980; Suppl 92: 44-47) were acceptable for hospital-based studies but were found not to be suitable for field studies. A UK working party formulated clinical diagnostic criteria that could be used in both hospital and epidemiological settings. Validation studies of the criteria showed widely variable results, probably due to different clinical settings and ethnicity. AIM AND OBJECTIVE: This study was undertaken to validate Hanifin and Rajka's criteria and to assess the comparative efficacy of their criteria and the UK working party's diagnostic criteria in the diagnosis of AD in a hospital setting in North India. SUBJECTS AND METHODS: This study serially included 101 patients with AD and 48 controls of paediatric age group. The study period was from July 2003 to December 2004. RESULTS: Hanifin and Rajka's criteria (sensitivity 96%, specificity 93.75%, positive predictive value 97% (PPV) and negative predictive value (NPV) 91.84%) had a statistical advantage over the UK working party's diagnostic criteria (sensitivity 86%, specificity 95.83%, PPV 97.75% and NPV 76.67%), with a P-value < 0.005. 相似文献
8.
S D Hobbs R Sam A Rehman T Marshall A B Wilmink A W Bradbury 《European journal of vascular and endovascular surgery》2003,26(3):322-324
BACKGROUND: The epidemiology of superficial venous disease is relatively well defined in the U.K. Caucasian population. By contrast, there are currently no data available for Asians, who comprise 3.6% of the U.K., and 14.1% of this institution's catchment population. The aim of this study was to compare surgery for superficial venous disease in Caucasians and Asians in this institution, in the context of our local population. METHODS: A prospectively gathered database of all 2011 superficial venous operations performed between January 1997 and April 2002 was retrospectively analysed with regard to ethnicity. The ethnic, gender and age composition of our catchment area was determined from U.K. census data. The full institutional records of 100 Asian and 100 randomly selected age and sex-matched Caucasian patients were compared in a case control study. RESULTS: After adjusting for age and gender according to census data, Asians were 40% less likely to undergo superficial venous surgery (SVS). Considering the 2011 operated patients as a whole, Asians were significantly younger and more likely to be male. In the case control study, Asians were significantly less likely to be operated for recurrent disease and significantly more likely to be operated for advanced disease. CONCLUSIONS: Although Asians are significantly less likely to undergo SVS; those that do are more likely to be young, male and operated for skin changes and ulcers. This strongly suggests that the under-representation of Asians is due to cultural, genetic or environmental factors and unmet health care need, rather than a lower prevalence of clinically significant venous disease in the Asian population. 相似文献
9.
SUMMARY Impotence is a common symptom which can cause considerable distress to both the sufferer and his partner. The use of pharmacotherapy to improve erectile function will continue to increase as safe and effective drugs are developed. However, restoring erectile function should not be the only treatment objective. It is also essential to address personal and emotional factors in the sufferer, conflicts in his relationship with his partner, and sexual problems in his partner, all of which may be instrumental in causing or maintaining the presenting impotence. We advocate a combined approach with appropriate medical treatment and sex and couple therapy 相似文献
10.
The pelvic congestion syndrome 总被引:4,自引:0,他引:4
J T Hobbs 《British journal of hospital medicine》1990,43(3):200-206
Perivulval varices appear during pregnancy and usually disappear after delivery but become more prominent with subsequent pregnancies. They may extend over the buttock and may be associated with recurrent leg varices. Some patients have extensive varices in the broad ligaments and present with the pelvic congestion syndrome. These patients have been shown to have grossly dilated ovarian veins. Elimination of this proximal incompetence relieves the symptoms. 相似文献