全文获取类型
收费全文 | 2675篇 |
免费 | 377篇 |
国内免费 | 8篇 |
专业分类
耳鼻咽喉 | 8篇 |
儿科学 | 100篇 |
妇产科学 | 299篇 |
基础医学 | 185篇 |
口腔科学 | 29篇 |
临床医学 | 949篇 |
内科学 | 282篇 |
皮肤病学 | 53篇 |
神经病学 | 108篇 |
特种医学 | 324篇 |
外科学 | 245篇 |
综合类 | 75篇 |
一般理论 | 5篇 |
预防医学 | 154篇 |
眼科学 | 9篇 |
药学 | 92篇 |
中国医学 | 2篇 |
肿瘤学 | 141篇 |
出版年
2023年 | 43篇 |
2021年 | 11篇 |
2020年 | 39篇 |
2019年 | 25篇 |
2018年 | 69篇 |
2017年 | 96篇 |
2016年 | 84篇 |
2015年 | 106篇 |
2014年 | 115篇 |
2013年 | 143篇 |
2012年 | 59篇 |
2011年 | 83篇 |
2010年 | 109篇 |
2009年 | 116篇 |
2008年 | 65篇 |
2007年 | 70篇 |
2006年 | 61篇 |
2005年 | 52篇 |
2004年 | 57篇 |
2003年 | 53篇 |
2002年 | 51篇 |
2001年 | 65篇 |
2000年 | 44篇 |
1999年 | 82篇 |
1998年 | 101篇 |
1997年 | 118篇 |
1996年 | 117篇 |
1995年 | 101篇 |
1994年 | 73篇 |
1993年 | 54篇 |
1992年 | 49篇 |
1991年 | 63篇 |
1990年 | 35篇 |
1989年 | 58篇 |
1988年 | 64篇 |
1987年 | 50篇 |
1986年 | 62篇 |
1985年 | 62篇 |
1984年 | 30篇 |
1983年 | 36篇 |
1982年 | 30篇 |
1981年 | 19篇 |
1980年 | 27篇 |
1979年 | 29篇 |
1978年 | 24篇 |
1977年 | 31篇 |
1976年 | 23篇 |
1975年 | 24篇 |
1974年 | 11篇 |
1973年 | 11篇 |
排序方式: 共有3060条查询结果,搜索用时 15 毫秒
1.
2.
D Van Neste† RM Trüeb‡ 《Journal of the European Academy of Dermatology and Venereology》2006,20(5):578-583
BACKGROUND: Computer-assisted image analysis has been proposed for human hair growth studies. METHODS: The performances of Trichoscan, a commercially available automated system combining epiluminiscence microscopy with digital image analysis, developed for office-based hair growth measurements, have been evaluated comparatively on the same skin sites using standardized photographic equipment and calibrated processing for contrast-enhanced phototrichogram (CE-PTG) analysis. This reference method has been validated with scalp biopsies and histological examination of serial sectioning. RESULTS: Besides edge effects, hair fibres escaped the Trichoscan analysis for various reasons including, but not limited to, thickness, pigmentation, closeness and crossing. CONCLUSION: Most of these problems have been identified in the late 1980s and remain largely unsolved by the processing software that was evaluated in 2004. Therefore claims promoting the Trichoscan method for accurate hair measurements in clinical trials on scalp and body hair are not supported by the present investigation. The speed at which the analysis is performed is outweighed by the errors in signal detection. Therefore we suggest that improvements must be clearly documented before Trichoscan is established for quantified diagnostic purposes and detailed hair cycle monitoring during hair trials. 相似文献
3.
4.
L R Baker W J Mallinson M C Gregory E A Menzies W R Cattell H N Whitfield W F Hendry J E Wickham A M Joekes 《British journal of urology》1987,60(6):497-503
Sixty patients with idiopathic retroperitoneal fibrosis presenting between 1965 and 1984 are reviewed. Their mean age at presentation was 56 years and the male:female ratio was 3:1. The commonest presenting symptoms were flank and abdominal pain, weight loss, nausea and polyuria. Physical examination was usually normal, expect for the presence of hypertension. Anaemia and elevation of erythrocyte sedimentation rate were usually present. Proteinuria was found in less than a third of patients at presentation and significant bacteriuria was uncommon. The correct diagnosis was made or suspected in very few patients before referral. The cumulative actuarial survival rate was 86% at 1 year and 78% at 2 years. Seventeen patients died; they were significantly older and more uraemic at the time of referral than those who survived. A few patients did well with either corticosteroid therapy or ureterolysis alone. In the majority, both operation and steroid treatment were necessary. In bilateral obstruction with residual function in both kidneys, bilateral ureterolysis proved superior to unilateral operation (each followed by steroid therapy) in conserving renal function. Operation alone or steroid therapy alone should be considered in cases where steroids or surgery respectively present particular hazards. The less traumatic unilateral operation should be considered in poor risk patients and in those whose renal function is absent on one side. In many survivors, disease activity has persisted for many years. Life-long follow-up is recommended. 相似文献
5.
V Schleyer† S Radakovic-Fijan‡ S Karrer† T Zwingers§ A Tanew‡ M Landthaler† RM Szeimies† 《Journal of the European Academy of Dermatology and Venereology》2006,20(7):823-828
BACKGROUND: Based on good results in the treatment of superficial skin tumours, since the early 1990s topical photodynamic therapy with aminolaevulinic acid (ALA PDT) has been used for disseminated, inflammatory dermatoses including psoriasis. However, there is still a lack of well-documented trials. OBJECTIVE: A prospective randomized, double-blind phase I/II intrapatient comparison study was conducted in 12 patients to investigate whether topical ALA PDT is an effective treatment for chronic plaque-type psoriasis. METHODS: In each patient three psoriatic plaques were randomly treated with a light dose of 20 J/cm(2) and 0.1%, 1% and 5% ALA, respectively. Treatment was conducted twice a week until complete clearance or for a maximum of 12 irradiations. Therapeutic efficacy was assessed by weekly determination of the psoriasis severity index (PSI). RESULTS: The mean percentage improvement was 37.5%, 45.6% and 51.2% in the 0.1%, 1% and 5% ALA-treated groups, respectively. Irradiation had to be interrupted several times because of severe burning and pain sensation. CONCLUSION: Topical ALA PDT did not prove to be an appropriate treatment option for plaque-type psoriasis due to disappointing clinical efficacy, the time-consuming treatment procedure and its unfavourable adverse event profile. 相似文献
6.
7.
W F Hendry 《Fertility and sterility》1992,57(6):1342-1343
Fifteen subfertile males with absent or atrophic right testes underwent ligation of left varicoceles. Sperm concentration rose significantly with correction of scrotal thermographic abnormality and nine wives (60%) became pregnant. 相似文献
8.
9.
10.
W F Hendry 《Reproduction, fertility, and development》1989,1(3):205-20; discussion 220-2
Autoimmunity to spermatozoa results in the production of antisperm antibodies that usually reduce the fertility of human males. Many laboratory tests have been devised to detect antisperm antibodies, but the results of such tests do not always correlate well with each other, particularly when the tests are conducted with patients' own spermatozoa rather than donor sperm. Experience over the past 12 years at Chelsea Hospital for Women and St Bartholomew's Hospital in London has led to at Chelsea Hospital for Women and St Bartholomew's Hospital in London has led to the development of an effective method for testing and treating subfertile males. This involves using the mixed antiglobulin reaction test and the post-coital test as initial screening tests, followed by serum and seminal plasma agglutination tests (both gelatin and tray) and the sperm-cervical mucus contact tests. Suitable patients are then put on one of three steroid regimens--long-term low-dose prednisolone, intermittent high-dose methylprednisolone, or intermediate graduated-dose prednisolone. Such treatment is useful not only in cases of spontaneous autoimmunity, but also in cases involving genital infection, testicular obstruction, and in vitro fertilization or gamete intrafallopian transfer. 相似文献