全文获取类型
收费全文 | 771篇 |
免费 | 39篇 |
国内免费 | 29篇 |
专业分类
耳鼻咽喉 | 6篇 |
儿科学 | 27篇 |
妇产科学 | 12篇 |
基础医学 | 79篇 |
口腔科学 | 58篇 |
临床医学 | 80篇 |
内科学 | 146篇 |
皮肤病学 | 8篇 |
神经病学 | 20篇 |
特种医学 | 28篇 |
外科学 | 139篇 |
综合类 | 29篇 |
预防医学 | 82篇 |
眼科学 | 4篇 |
药学 | 89篇 |
中国医学 | 3篇 |
肿瘤学 | 29篇 |
出版年
2023年 | 10篇 |
2022年 | 9篇 |
2021年 | 36篇 |
2020年 | 23篇 |
2019年 | 26篇 |
2018年 | 28篇 |
2017年 | 23篇 |
2016年 | 20篇 |
2015年 | 15篇 |
2014年 | 31篇 |
2013年 | 43篇 |
2012年 | 56篇 |
2011年 | 63篇 |
2010年 | 40篇 |
2009年 | 33篇 |
2008年 | 33篇 |
2007年 | 43篇 |
2006年 | 41篇 |
2005年 | 37篇 |
2004年 | 27篇 |
2003年 | 26篇 |
2002年 | 18篇 |
2001年 | 16篇 |
2000年 | 12篇 |
1999年 | 8篇 |
1998年 | 5篇 |
1997年 | 4篇 |
1996年 | 10篇 |
1995年 | 11篇 |
1993年 | 9篇 |
1992年 | 5篇 |
1991年 | 6篇 |
1990年 | 6篇 |
1989年 | 9篇 |
1987年 | 9篇 |
1986年 | 4篇 |
1985年 | 3篇 |
1983年 | 4篇 |
1982年 | 6篇 |
1980年 | 5篇 |
1979年 | 7篇 |
1978年 | 2篇 |
1977年 | 1篇 |
1976年 | 1篇 |
1975年 | 3篇 |
1974年 | 2篇 |
1973年 | 1篇 |
1972年 | 1篇 |
1971年 | 3篇 |
1969年 | 1篇 |
排序方式: 共有839条查询结果,搜索用时 62 毫秒
1.
2.
3.
4.
Cerebral occlusive vasculopathy in systemic lupus erythematosus and speculation on the part played by complement.
下载免费PDF全文
![点击此处可从《Annals of the rheumatic diseases》网站下载免费的PDF全文](/ch/ext_images/free.gif)
A 35 year old woman with systemic lupus erythematosus and hypocomplementenaemia presented with new onset seizures and subsequently died. At necropsy, widespread microinfarctions of the cerebral cortex were found to be predominantly due to the formation of leucoaggregates within small blood vessels without any vasculitis. 相似文献
5.
LN Weinberger MJ Zirwas JC English III 《Journal of the European Academy of Dermatology and Venereology》2007,21(2):156-162
Male genital oedema can be defined as swelling or the appearance of swelling of the scrotum and/or the penile shaft and prepuce. Despite the various causes of genital oedema reported in the published work, a concise approach to the evaluation and management has not been sufficiently addressed. 相似文献
6.
Rana Roshane-Shahid Nazim Syed M. Ather M. Hammad 《International urology and nephrology》2021,53(1):21-26
International Urology and Nephrology - To evaluate the acute renal colic score (ARC) in predicting the need of emergency intervention (EI) in patients with ureteric colic secondary to a ureteral... 相似文献
7.
Yang PY Almofti MR Lu L Kang H Zhang J Li TJ Rui YC Sun LN Chen WS 《第二军医大学学报》2006,27(6):637-637
Polygonum multiflorum stilbeneglycoside (PMS) is a water-soluble fraction of Polygonum multiflorum Thunb. , one of the most famous tonic traditional Chinese medicines, that has protective effects on the cardiovascular system. The purpose of the present study is to elucidate the effects of PMS on macrophage-derived foam cell functions and the reduction of severity of atherosclerosis in hypercholesterolemic New Zealand White (NZW) rabbits. NZW rabbits were fed for 12 weeks with a normal diet, a high cholesterol diet, or a high cholesterol diet associated with irrigation with different doses of PMS (25, 50, or 100 mg/kg). Treatment of NZW rabbits fed with high cholesterol diet with 100 mg/kg PMS attenuated the increase in plasma cholesterol, low-density lipoprotein cholesterol, very low-density lipoprotein cholesterol, and plasma triglyceride. Treatment with 50 and 100 mg/kg PMS caused 43% and 60% decrease in atherosclerotic lesioned area ratio to total surface area, respectively. In U937 foam cells, PMS could decrease the high expression of intercellular adhesion molecule (ICAM)-1 protein and the vascular endothelial growth factor (VEGF) protein levels in the medium induced by oxidized lipoprotein when analyzed by flow cytometry. The results proved that PMS is a powerful agent against atherosclerosis and that PMS action could possibly be through the inhibition of the expression of ICAM-1 and VEGF in foam cells. 相似文献
8.
In vivo chondroprotection and metabolic synergy of glucosamine and chondroitin sulfate 总被引:5,自引:0,他引:5
Lippiello L Woodward J Karpman R Hammad TA 《Clinical orthopaedics and related research》2000,(381):229-240
Supplements of glucosamine hydrochloride, low molecular weight chondroitin sulfate, and manganese ascorbate were tested separately and in combination for their ability to retard progression of cartilage degeneration in a rabbit instability model of osteoarthrosis. Computerized quantitative histologic evaluation of safranin O stained sections of the medial femoral condyles measured the grade and extent of tissue involvement of lesions. Severe lesions (Mankin grade greater than 7) were absent in all animals supplemented with a dietary mixture of glucosamine, chondroitin sulfate, and manganese ascorbate. Total linear involvement (mm of lesioned surface) and total grade (mean grade x number of lesions per animal) were reduced significantly in animals given the combination compared with controls (59% and 74% respectively). Animals supplemented with glucosamine, chondroitin sulfate, or manganese ascorbate alone had less moderate and severe tissue involvement than controls but not to the extent of the combined group. In vitro, a combination of glucosamine hydrochloride and chondroitin sulfate acted synergistically in stimulating glycosaminoglycan synthesis (96.6%). Chondroitin sulfate and manganese ascorbate but not glucosamine were effective in inhibiting degradative enzyme activity. These data suggest that the disease modifying effect (the ability to retard progression of cartilage degeneration) of a mixture of glucosamine, chondroitin sulfate, and manganese ascorbate is more efficacious than either agent alone. 相似文献
9.
10.