全文获取类型
收费全文 | 199篇 |
免费 | 20篇 |
专业分类
耳鼻咽喉 | 2篇 |
儿科学 | 3篇 |
妇产科学 | 7篇 |
基础医学 | 33篇 |
口腔科学 | 21篇 |
临床医学 | 18篇 |
内科学 | 46篇 |
皮肤病学 | 1篇 |
神经病学 | 14篇 |
特种医学 | 3篇 |
外科学 | 33篇 |
综合类 | 2篇 |
预防医学 | 4篇 |
眼科学 | 12篇 |
药学 | 4篇 |
中国医学 | 5篇 |
肿瘤学 | 11篇 |
出版年
2022年 | 2篇 |
2021年 | 3篇 |
2020年 | 2篇 |
2019年 | 7篇 |
2018年 | 4篇 |
2017年 | 4篇 |
2016年 | 6篇 |
2015年 | 3篇 |
2014年 | 8篇 |
2013年 | 13篇 |
2012年 | 21篇 |
2011年 | 21篇 |
2010年 | 6篇 |
2009年 | 9篇 |
2008年 | 12篇 |
2007年 | 14篇 |
2006年 | 11篇 |
2005年 | 11篇 |
2004年 | 11篇 |
2003年 | 13篇 |
2002年 | 10篇 |
2001年 | 1篇 |
2000年 | 3篇 |
1999年 | 1篇 |
1998年 | 2篇 |
1997年 | 1篇 |
1996年 | 2篇 |
1994年 | 3篇 |
1993年 | 1篇 |
1992年 | 2篇 |
1989年 | 1篇 |
1987年 | 1篇 |
1986年 | 2篇 |
1985年 | 1篇 |
1983年 | 1篇 |
1981年 | 1篇 |
1974年 | 1篇 |
1972年 | 2篇 |
1971年 | 1篇 |
1964年 | 1篇 |
排序方式: 共有219条查询结果,搜索用时 406 毫秒
1.
2.
Alobeid B Pan LX Milligan L Budel L Frizzera G 《American journal of clinical pathology》2004,121(1):43-50
We describe 3 patients who had oral mucosal lesions with features of traumatic eosinophilic granuloma (TEG) and containing CD30+ atypical cells. In 1 patient, the oral lesion was followed by skin nodules. All lesions were evaluated histologically, by immunohistochemical analysis, and by polymerase chain reaction (PCR) analysis of the T-cell receptor (TCR) gamma chain gene. All oral lesions were characterized by a dense and deeply infiltrative lymphoproliferation, showing epitheliotropism and massive eosinophilia. They contained atypical large lymphoid cells, which expressed T-cell markers and CD30. PCR analysis showed a monoclonal rearrangement of the TCR gamma chain gene in all lesions and, in 1 patient, the same rearrangement in the oral and cutaneous specimens. The lesions in these patients seem to be the oral counterpart of the spectrum of primary cutaneous CD30+ lymphoproliferative disorders and should be recognized as such to avoid a diagnosis of large T-cell lymphoma and possible consequent overtreatment. However, they represent only a subset among several others within the complex and heterogeneous category of disorders referred to as TEG. 相似文献
3.
GATA3 expression in primary vulvar Paget disease: a potential pitfall leading to misdiagnosis of pagetoid urothelial intraepithelial neoplasia
下载免费PDF全文
![点击此处可从《Histopathology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
4.
5.
Rostagno A Frizzera G Ylagan L Kumar A Ghiso J Gallo G 《British journal of haematology》2002,119(1):62-69
Tumoral monoclonal immunoglobulin (Ig) light chain non-fibrillar deposits ('aggregomas'), which can be considered analogous to solitary light chain amyloidomas, are a rare presenting feature of B-cell dyscrasias. It is not certain if they are truly localized or if in reality they represent an initial expression of a silent systemic non-amyloid light chain deposition disease (LCDD). This report describes three patients, two of whom presented with cervical masses and the third with a solitary lung nodule, each comprising granular aggregates of monoclonal kappa light chain. Extracted deposits from the lymph node of one patient were shown by N-terminal amino acid sequence analysis to belong to the variable-region kappa I (Vkappa I) light chain subgroup, the first reported kappa-LCDD protein encoded by the L9 gene and the first report of an expressed protein related to this gene. Extracted deposits from the lung nodule of the second patient belonged to the Vkappa IV light chain subgroup encoded by the B3 germ line gene. The N-terminal amino acid sequences of the light chains from the aggregomas were compared with the related germ line sequences and to the N-terminal amino acid sequences of the nine other known kappa-LCDD light chains reported thus far from patients with systemic LCDD. 相似文献
6.
Letícia Carnaz Cristiane S. Moriguchi Ana Beatriz de Oliveira Paulo R.P. Santiago Glauco A.P. Caurin Gert-Åke Hansson Helenice J.C. Gil Coury 《Medical engineering & physics》2013,35(11):1629-1637
This study compared neck range of movement recording using three different methods goniometers (EGM), inclinometers (INC) and a three-dimensional video analysis system (IMG) in simultaneous and synchronized data collection. Twelve females performed neck flexion-extension, lateral flexion, rotation and circumduction. The differences between EGM, INC, and IMG were calculated sample by sample. For flexion-extension movement, IMG underestimated the amplitude by 13%; moreover, EGM showed a crosstalk of about 20% for lateral flexion and rotation axes. In lateral flexion movement, all systems showed similar amplitude and the inter-system differences were moderate (4–7%). For rotation movement, EGM showed a high crosstalk (13%) for flexion-extension axis. During the circumduction movement, IMG underestimated the amplitude of flexion-extension movements by about 11%, and the inter-system differences were high (about 17%) except for INC–IMG regarding lateral flexion (7%) and EGM–INC regarding flexion-extension (10%). For application in workplace, INC presents good results compared to IMG and EGM though INC cannot record rotation. EGM should be improved in order to reduce its crosstalk errors and allow recording of the full neck range of movement. Due to non-optimal positioning of the cameras for recording flexion–extension, IMG underestimated the amplitude of these movements. 相似文献
7.
Paola Turchiello da SILVA Luciana Dapieve PATIAS Glauco da Costa ALVAREZ Vanessa Ramos KIRSTEN Elisangela COLPO Cristina Machado Bragan?a de MORAES 《Brazilian archives of digestive surgery》2015,28(4):270-273
Background :
Nowadays obesity is a chronic disease considered one of the greatest problems in public healthy. Showing to be effective in a short and long term, the bariatric surgery has emerged as an optional treatment for morbid obesity.Aim:
Identify the profile of patients seeking bariatric surgery.Methods:
Were interviewed 100 patients in preoperative nutritional monitoring of bariatric surgery. The study was conducted by applying a questionnaire prepared according to the research objectives.Results:
From the individuals that were seeking bariatric surgery, 78% were female, 62% were married and 69% reported physical activity. The average age of those surveyed was 37±10.83 years and mean body mass index (BMI) was 43.51± 6.25 kg/m². The comorbidity more prevalent in this group was high blood pressure (51%). In previous treatments for weight reduction, 92% have already done hypocaloric diet followed by anorectic drug (83%). The success of these treatments was reported by 92% of patients; however, the weight lost was recovered in less than one year of 75%. Patients with diabetes mellitus and dyslipidemia had higher BMI values. The patients with comorbidities showed lower levels of BMI.Conclusion:
The profile of patients who sought surgical treatment for their obesity were predominantly women with a family background of obesity and obesity-related comorbidities, especially hypertension and diabetes mellitus. 相似文献8.
Autoimmune lymphoproliferative disease (ALD) is a rare familial disorder. Clinical and laboratory features of this disease
include a generalized lymphadenopathy, splenomegaly, increased levels of circulating CD3+ with low levels of CD4+, CD8+ T-cells,
and autoimmune phenomena, characteristics that the autoimmune lymphoproliferative syndrome (ALPS) have in common. Treatment
usually consists of different supportive therapies. We report on the case of a young man affected by ALD who became resistant
to steroids and was unresponsive to cyclosporine. Nevertheless, he was successfully treated with interferon (IFN)-α, resulting
in a long-lasting, clinically complete remission.
Received: 29 November 1999 / Accepted: 29 June 2000 相似文献
9.
Kelly Cristina Lira de Andrade Pedro de Lemos Menezes Aline Tenório Lins Carnaúba Renato Glauco de Sousa Rodrigues Mariana de Carvalho Leal Liliane Desgualdo Pereira 《Clinics (S?o Paulo, Brazil)》2013,68(6):815-819
OBJECTIVE:
The audibility thresholds for the sound frequency of 137 upward- and downward-sloping audiograms showing sensorineural hearing loss were selected and analyzed in conjunction with speech recognition thresholds obtained from individuals seen at a public otolaryngology clinic to determine which frequencies in slope audiograms best represent speech recognition thresholds.METHOD:
The linear regression model and mean square error were used to determine the associations between the threshold values.RESULT:
The mean square error identified larger errors when using thresholds of 500, 1000, and 2000 Hz than when using audibility thresholds of 500, 1000, 2000, and 4000 Hz. The linear regression model showed a higher correlation (91%) between the audiogram thresholds for frequencies of 500, 1000, 2000, and 4000 Hz than for the frequencies of 500, 1000, and 2000 Hz (88%).CONCLUSION:
Frequencies of 500, 1000, 2000, and 4000 Hz were the most significant in predicting the speech recognition threshold. 相似文献10.