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EVELYNE GOUDREAU M.D. GEORGE W. VETROVEC M.D. GERMANO DISCIASCIO M. D. 《Journal of interventional cardiology》1988,1(3):181-187
Different techniques have been used to perform coronary angioplasty of bifurcational lesions. Advantages and disadvantages of the kissing balloon technique, the single guiding-double wire technique, and the double Probe(tm) technique are reviewed. We describe a new technique for coronary angioplasty of bifurcational lesions through a single guiding catheter that has advantages of both the over-the-wire and the Probe(tm) systems. 相似文献
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Health policy, epidemiology and power: the interest web 总被引:4,自引:4,他引:0
The relation between epidemiological research results and policy-making is reviewed. Apparently, traditional models of policy-making(incrementalism, mixed scanning synoptic planning) do not explainwhy research findings are hardly used in policy-making procedures. It is suggested that this phenomenon is related to three determinantsof policy-making: (i) a bias stemming from sets of causal, finaland normative assumptions and presuppositions; (ii) interestwebs of groups in certain domains; and (iii) the power of organizationsto monitor and communicate. The conclusion is that epidemiologistsshould engage in the policy-making process more consciouslyand conscientiously. 相似文献
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In the developing vertebrate retina, ganglion cells fire spontaneous bursts of action potentials long before the eye becomes exposed to sensory experience at birth. These early bursts are synchronised between neighbouring retinal ganglion cells (RGCs), yielding unique spatiotemporal patterns: ‘waves’ of activity sweep across large retinal areas every few minutes. Both at retinal and extraretinal levels, these embryonic retinal waves are believed to guide the wiring of the visual system using hebbian mechanisms of synaptic strengthening. In the first part of this review, we recapitulate the evidence for a role of these embryonic spontaneous bursts of activity in shaping developing complex receptive field properties of RGCs in the turtle embryonic retina. We also discuss the role of visual experience in establishing RGC visual functions, and how spontaneous activity and visual experience interact to bring developing receptive fields to maturation. We have hypothesised that the physiological changes associated with development reflect modifications in the dendritic arbours of RGCs, the anatomical substrate of their receptive fields. We demonstrate that there is a temporal correlation between the period of receptive field expansion and that of dendritic growth. Moreover, the immature spontaneous activity contributes to dendritic growth in developing RGCs. Intracellular staining of RGCs reveals, however, that immature receptive fields only rarely show direct correlation with the layout of the corresponding dendritic tree. To investigate the possibility that not only the presence of the spontaneous activity, but even the precise spatiotemporal patterns encoded in retinal waves might contribute to the refinement of retinal neural circuitry, first we must clarify the mechanisms mediating the generation and propagation of these waves across development. In the second part of this review, we present evidence that turtle retinal waves, visualised using calcium imaging, exhibit profound changes in their spatiotemporal patterns during development. From fast waves sweeping across large retinal areas and recruiting many cells on their trajectory at early stages, waves become slower and eventually stop propagating towards hatching, when they become stationary patches of neighbouring coactive RGCs. A developmental switch from excitatory to inhibitory GABAA responses appears to mediate the modification in spontaneous activity patterns while the retina develops. Future chronic studies using specific spatiotemporal alterations of the waves will shed a new light on how the wave dynamics help in sculpting retinal receptive fields. 相似文献
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CYRILLE BASTIDE FREDERIC ARROUA AURELIEN CARCENAC ERIC ANFOSSI EVELYNE RAGNI DOMINIQUE ROSSI 《International journal of urology》2006,13(5):608-610
Primary malignant melanoma of the adrenal gland is an established entity. Fewer than 20 cases have been reported in the published literature. Because of the high frequency of adrenal gland metastases from malignant melanoma and pigmented pheochromocytoma, several rigid diagnostic criteria have been established for accepting an adrenal melanoma as primary. A new case is reported in this article. This observation is an opportunity update the literature on the diagnostic difficulties in this rare pathology. 相似文献
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Coronary angioplasty of very distal or subtotal lesions has been markedly improved with the recent development of the ProbeTM dilatation catheter. However, despite its very low profile, the ProbeTM has certain limitations. We describe a new device. the Probing CatheterTM , that, in conjunction with the ProbeTM increases the success rate and facilitates coronary angioplasty of very distal or high grade lesions. 相似文献
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CLAUS H. REINHARDT NADINE LÖPKER MICHAEL J. NOACK EVELYNE ROSEN & KLAUS KLEIN 《International journal of paediatric dentistry / the British Paedodontic Society [and] the International Association of Dentistry for Children》2009,19(5):354-359
Background. Focused caries prevention programmes for migrant children often fail because there is an important barrier of linguistic and cultural diversity.
Aim. The aim of this study was to evaluate whether a tailored peer teaching approach can improve oral health behaviours of underprivileged and/or multinational migrant first graders.
Design. Two fourth grade classes (30 children, mean age 9.6) and two first grade classes (38 children, mean age 6.6) with high migrant background participated. The fourth graders took part in a preparatory course of oral health and developed a concept for tutoring first graders in oral health concepts as well as the Fones toothbrushing method. Later then, the fourth graders instructed the first graders during two lessons. Toothbrushing of each first grader was filmed before and 7 days after instruction. Toothbrushing time, method, and systematic were evaluated.
Results. After instruction, circular toothbrushing movements and systematic toothbrushing were observed significantly more often ( P = 0.0001); toothbrushing time did not change.
Conclusions. This pilot study shows that tutoring by older peers of similar origin resulted in significant changes towards better oral health in underprivileged and/or multinational migrant first graders. Authentic role models could be provided, and communication and cultural barriers circumvented. 相似文献
Aim. The aim of this study was to evaluate whether a tailored peer teaching approach can improve oral health behaviours of underprivileged and/or multinational migrant first graders.
Design. Two fourth grade classes (30 children, mean age 9.6) and two first grade classes (38 children, mean age 6.6) with high migrant background participated. The fourth graders took part in a preparatory course of oral health and developed a concept for tutoring first graders in oral health concepts as well as the Fones toothbrushing method. Later then, the fourth graders instructed the first graders during two lessons. Toothbrushing of each first grader was filmed before and 7 days after instruction. Toothbrushing time, method, and systematic were evaluated.
Results. After instruction, circular toothbrushing movements and systematic toothbrushing were observed significantly more often ( P = 0.0001); toothbrushing time did not change.
Conclusions. This pilot study shows that tutoring by older peers of similar origin resulted in significant changes towards better oral health in underprivileged and/or multinational migrant first graders. Authentic role models could be provided, and communication and cultural barriers circumvented. 相似文献