全文获取类型
收费全文 | 1491篇 |
免费 | 108篇 |
国内免费 | 6篇 |
专业分类
耳鼻咽喉 | 15篇 |
儿科学 | 71篇 |
妇产科学 | 17篇 |
基础医学 | 176篇 |
口腔科学 | 16篇 |
临床医学 | 187篇 |
内科学 | 267篇 |
皮肤病学 | 6篇 |
神经病学 | 70篇 |
特种医学 | 95篇 |
外科学 | 191篇 |
综合类 | 14篇 |
一般理论 | 1篇 |
预防医学 | 252篇 |
眼科学 | 41篇 |
药学 | 77篇 |
中国医学 | 6篇 |
肿瘤学 | 103篇 |
出版年
2023年 | 17篇 |
2022年 | 78篇 |
2021年 | 97篇 |
2020年 | 42篇 |
2019年 | 54篇 |
2018年 | 60篇 |
2017年 | 25篇 |
2016年 | 41篇 |
2015年 | 53篇 |
2014年 | 45篇 |
2013年 | 62篇 |
2012年 | 83篇 |
2011年 | 72篇 |
2010年 | 34篇 |
2009年 | 36篇 |
2008年 | 74篇 |
2007年 | 62篇 |
2006年 | 65篇 |
2005年 | 80篇 |
2004年 | 56篇 |
2003年 | 51篇 |
2002年 | 47篇 |
2001年 | 28篇 |
2000年 | 28篇 |
1999年 | 34篇 |
1998年 | 9篇 |
1997年 | 10篇 |
1996年 | 6篇 |
1995年 | 10篇 |
1994年 | 13篇 |
1993年 | 9篇 |
1992年 | 10篇 |
1991年 | 13篇 |
1990年 | 13篇 |
1989年 | 24篇 |
1988年 | 14篇 |
1987年 | 19篇 |
1986年 | 13篇 |
1985年 | 18篇 |
1984年 | 20篇 |
1983年 | 5篇 |
1981年 | 6篇 |
1979年 | 8篇 |
1978年 | 6篇 |
1976年 | 6篇 |
1975年 | 8篇 |
1973年 | 5篇 |
1972年 | 6篇 |
1971年 | 4篇 |
1967年 | 6篇 |
排序方式: 共有1605条查询结果,搜索用时 15 毫秒
1.
William M. Chadduck Duc H. Duong John M. Kast David J. Donahue 《Child's nervous system》1995,11(10):579-583
Cerebellar hemorrhage is a devastating condition with morbidity and mortality related not only to the etiology of the hemorrhage, but also to the timing of the intervention. Sixteen consecutive pediatric patients with acute cerebellar hemorrhages are presented: 6 had vascular abnormalities, 3 had tumors, and 2 had hemorrhages of unknown etiology. Thirteen of the 16 patients survived with only 1 of the 13 having persistent vegetative state as a neurologic outcome. Six of 8 patients presenting in a moribund condition had good outcomes, and 3 of 4 patients presenting with fixed and dilated pupils also had good outcomes. Thus, in contrast to adults, rapid evaluation by CT scanning, followed by the judicious use of ventricular drainage and prompt surgical treatment, have resulted in favorable outcomes in pediatric patients despite their poor clinical presentations. None of the neonates having cerebellar hemorrhages required surgical intervention; their courses could be followed clinically and with transfontanel ultrasound.Presented as a poster at the 14th Congress of the European Society for Paediatric Neurosurgery, Lyon, France, 21–23 September 1994, and the XXII Annual Meeting of the International Society for Pediatric Neurosurgery, Birmingham, UK, 25–28 September 1994 相似文献
2.
The authors report their experience of percutaneous nephrolithotomy over a period of three years. The analysis of the first 250 cases performed reveals a low morbidity, with serious complications in 1% of cases, and an acceptable complete success rate of 83%. The indications for percutaneous nephrolithotomy have been modified since the opening of an extracorporeal lithotripsy unit. The choice between the two techniques depends on their efficacy and their expected morbidity based on four criteria: the volume, chemical composition and site of the stone and the morphology of the upper urinary tract. Percutaneous nephrolithotomy is the treatment of choice for large stones (greater than 2.5 cm), hard stones or those formed proximally to a stenotic lesion of the urinary tract, which can then be dilated at the same procedure. A combination of the two methods is sometimes uses to treat staghorn calculi with a success rate of 80%. On the other hand, very large staghorn calculi with caliceal branches are best treated by open surgery. 相似文献
3.
Since the last two decades, rapid progress has been made in the field of cancer immunotherapy relevant to manipulation of adaptative cytotoxic T lymphocytes (CTLs) and innate immunity natural killer (NK) cells as well as antibodies. Many possibilities are now offered for therapeutic purposes contributing to better approaches in treatment of cancer. 相似文献
4.
Robert Ritch Jeffrey M. Liebmann H. Viet Tran 《American journal of ophthalmology》2003,136(2):395-396
5.
C Duc I Barakat-Walter E Philippe B Droz 《Brain research. Developmental brain research》1991,59(2):209-219
The expression of substance P (SP) was studied in sensory neurons of developing chick lumbosacral dorsal root ganglia (DRG) by using a mixture of periodic acid, lysine and paraformaldehyde as fixative and a monoclonal antibody for SP-like immunostaining. The first SP-like-immunoreactive DRG cells appeared first at E5, then rapidly increased in number to reach a peak (88% of ganglion cells) at E8, and finally declined (59% at E12, 51% after hatching). The fall of the SP-like-positive DRG cells resulted from two concomitant events affecting a subset of small B-neurons: a loss of neuronal SP-like immunoreactivity and cell death. After one hindlimb resection at an early (E6) or late (E12) stage of development (that is before or after establishment of peripheral connections), the DRG were examined 6 days later. In both cases, a drastic neuronal death occurred in the ispilateral DRG. However, the resection at E6 did not change the percentage of SP-like-positive neurons, while the resection at E12 severely reduced the proportion of SP-like-immunoreactive DRG cells (25%). In conclusion, connections established between DRG and peripheral target tissues not only promote the survival of sensory neurons, but also control the maintenance of SP-like-expression. Factors issued from innervated targets such as NGF would support the survival of SP-expressing DRG cells and enhance their SP content while other factors present in skeletal muscle or skin would hinder SP expression and therefore lower SP levels in a subset of primary sensory neurons. 相似文献
6.
X Favereau T Corcos P Duc P Quennevat E Benarroch P Desoutter 《Archives des maladies du coeur et des vaisseaux》1988,81(7):903-906
Owing to the ever growing practice of coronary angioplasty, each patient is subjected to multiple examinations and it has become imperative, both for ethical and functional reasons, to reduce the morbidity of coronary arteriography. For this purpose, reduction in the caliber of catheters is a step forward which must be made without altering the procedure and even while making it simpler (shorter stay in bed and in hospital). Between april, 1986 and january, 1987, 300 consecutive coronary arteriographies were performed in a uniform manner and using 5 French catheters in 239 men (mean age 55.4 years) and 61 women (mean age 60.3 years). There were 13 "failures" (4 p. 100) in the sense that the examination was pursued with conventional 7 F or 8 F catheters, or that the brachial route was used. Bilateral femoral puncture was necessary in 6 cases (2 p. 100), and 2 complications (0.7 p. 100) were observed: subacute femoral thrombosis in one case, and regressive cerebral vascular accident in another patient. Thus, it seems permissible and more convenient nowadays to perform all coronary arteriographies with a 5 French catheter. The femoral route can be used in ambulatory patients who get up 4 hours after the procedure. 相似文献
7.
8.
We report here the case of a patient suffering from idiopathic cold urticaria who did not respond to H1 antihistamine but who responded dramatically to the combination of H1 and H2 antagonists. Under H1 treatment, the urticaria was florid and the ice cube test clearly positive. After the addition of an H2 antihistamine, all the symptoms disappeared and the ice cube test became negative. The different therapeutic schedules proposed thereafter, showed that only the combination therapy was effective H1 antihistamine alone or H2 antihistamine alone being unable to modify the course of the disease. 相似文献
9.
10.
Randomized comparison of transurethral electroresection and holmium: YAG laser vaporization for symptomatic benign prostatic hyperplasia 总被引:3,自引:0,他引:3
Mottet N Anidjar M Bourdon O Louis JF Teillac P Costa P Le Duc A 《Journal of endourology / Endourological Society》1999,13(2):127-130
OBJECTIVE: To evaluate the safety and efficacy of holmium:YAG laser vaporization v transurethral electroresection (TURP) for benign prostatic hyperplasia. PATIENTS AND METHODS: Thirty-six patients were randomized. Two laser procedures (60 to 80 W) were performed for one TURP. Symptom Score, peak flow rate, potency, and ejaculation status were measured at baseline and at 1, 3, 6, and 12 months. RESULTS: The mean operative time was 75 minutes for laser and 56 minutes for TURP (P = 0.0407). With a mean laser energy delivered of 103.6 kJ, hemostasis was satisfactory during vaporization. The mean catheterization time was 1.7 and 2.1 days in the laser and TURP group, respectively. For the laser and TURP groups, the mean AUA Score improved from 20 preoperatively to 7 and from 24.1 to 5, respectively, at 12 months. The mean peak flow increased from 8.4 to 19.5 mL/sec and from 7.6 to 16.8 ml/sec, respectively, at 12 months. These results are not statistically different. No significant initial dysuria occurred. No significant difference between the groups appeared in potency or ejaculatory status during the follow-up. One patient in the laser group (Day 5) and two in the TURP group (2nd and 6th month) had to undergo a second procedure to relieve obstruction. CONCLUSION: Although taking slightly longer to accomplish, holmium:YAG laser vaporization of BPH provides early results very similar to those of TURP with a shorter catheterization time and no initial dysuria or pain. 相似文献