全文获取类型
收费全文 | 1384篇 |
免费 | 91篇 |
国内免费 | 9篇 |
专业分类
耳鼻咽喉 | 32篇 |
儿科学 | 34篇 |
妇产科学 | 38篇 |
基础医学 | 178篇 |
口腔科学 | 16篇 |
临床医学 | 119篇 |
内科学 | 309篇 |
皮肤病学 | 20篇 |
神经病学 | 63篇 |
特种医学 | 97篇 |
外科学 | 134篇 |
综合类 | 83篇 |
一般理论 | 3篇 |
预防医学 | 80篇 |
眼科学 | 43篇 |
药学 | 131篇 |
中国医学 | 11篇 |
肿瘤学 | 93篇 |
出版年
2023年 | 17篇 |
2022年 | 23篇 |
2021年 | 26篇 |
2020年 | 16篇 |
2019年 | 30篇 |
2018年 | 27篇 |
2017年 | 32篇 |
2016年 | 40篇 |
2015年 | 33篇 |
2014年 | 53篇 |
2013年 | 50篇 |
2012年 | 69篇 |
2011年 | 78篇 |
2010年 | 62篇 |
2009年 | 61篇 |
2008年 | 81篇 |
2007年 | 90篇 |
2006年 | 80篇 |
2005年 | 54篇 |
2004年 | 54篇 |
2003年 | 52篇 |
2002年 | 41篇 |
2001年 | 24篇 |
2000年 | 21篇 |
1999年 | 36篇 |
1998年 | 30篇 |
1997年 | 23篇 |
1996年 | 23篇 |
1995年 | 11篇 |
1994年 | 17篇 |
1993年 | 13篇 |
1992年 | 15篇 |
1991年 | 26篇 |
1990年 | 16篇 |
1989年 | 30篇 |
1988年 | 21篇 |
1987年 | 16篇 |
1986年 | 12篇 |
1985年 | 14篇 |
1984年 | 10篇 |
1983年 | 9篇 |
1981年 | 5篇 |
1980年 | 3篇 |
1979年 | 4篇 |
1977年 | 3篇 |
1976年 | 5篇 |
1974年 | 4篇 |
1973年 | 3篇 |
1972年 | 3篇 |
1971年 | 5篇 |
排序方式: 共有1484条查询结果,搜索用时 15 毫秒
1.
Emile Gogineni Zaker Rana Michael Wotman Jessie Karten Adam Riegel Mihaela Marrero Luis Maduro Dev Kamdar Douglas Frank Doru Paul Nagashree Seetharamu Maged Ghaly 《Journal of Geriatric Oncology》2021,12(1):122-127
PurposeManagement of head and neck cancers (HNC) in older adults is a common but challenging clinical scenario. We assess the impact of Stereotactic Body Radiation Therapy (SBRT) on survival utilizing the Geriatric-8 (G8) questionnaire.Materials and methods171 HNC patients, deemed medically unfit for definitive treatment, were treated with SBRT ± systemic therapy. G8 questionnaires were collected at baseline, at 4–6 weeks, and at 2–3 months post-treatment. Patients were stratified according to their baseline G8 score: <11 as ‘vulnerable’, 11–14 as ‘intermediate’, and >14 as ‘fit’. Overall survival (OS) was assessed through univariate Kaplan Meier analysis. Repeated measures ANOVA was used to determine if baseline characteristics affected G8 score changes.ResultsMedian follow-up was seventeen months. 60% of patients presented with recurrent HNC, 30% with untreated HNC primaries, and 10% with metastatic non-HNC primaries. Median age was 75 years. Median Charlson Comorbidity Index score was 2. 51% of patients were ‘vulnerable’, 37% were ‘intermediate’, and 12% were ‘fit' at baseline, with median survival of 13.2, 24.3, and 41.0 months, respectively (p = .004). Patients who saw a decrease in their follow-up G8 score (n = 69) had significantly lower survival than patients who had stable or increased follow-up G8 scores (n = 102), with median survival of 8.6 vs 36.0 months (p < .001).ConclusionThe G8 questionnaire may be a useful tool in upfront treatment decision-making to predict prognosis and prevent older patients from receiving inappropriate anti-cancer treatment. Decline in follow-up G8 scores may also predict worse survival and aid in goals of care following treatment. 相似文献
2.
3.
In contrast with cross-sectional designs used in previous studies, this exploratory study compared survey data from 127 matched pairs of clinical pharmacists and physicians working together. Physicians' perceptions of the importance of clinical pharmacy activities for patient care and the competence of pharmacists performing the activities were examined for their influence on prescribing behavior in an institutional setting. Data from a national survey showed that physicians rated pharmacists higher regarding recommendations based on drug use evaluations (p = 0.004) and competency to provide all clinical pharmacy services. Scores for pharmacokinetics ratings were similar between pharmacists and physicians (p = 0.168). Pharmacists rated the importance of recommendations based on cost-effectiveness higher than physicians (p = 0.012). Overall, physicians' perceptions of activity importance for patient care and pharmacist competency appear to dictate pharmacists' influence on physician prescribing behavior (R = 0.723). 相似文献
4.
5.
We report a case of malakoplakia in association with colonic adenocarcinoma. Tumour-associated malakoplakia in the gastrointestinal tract is a rare finding, generally confined to the colon. It may be locally aggressive, with invasion of pericolic tissues, but is always located adjacent to the tumour. This contrasts with the often more diffuse, multifocal distribution of colonic malakoplakia in association with other pathologies. 相似文献
6.
Resistant strains of Escherichia coli were obtained by stepwise cultivation in subinhibitory concentrations of two antimicrobially active amine oxides. Changes in the chemical composition of the outer membrane of the resistant strains were accompanied also by different antigenic reactions. New precipitation lines were revealed by double immunodiffusion and immuno-electrophoretic methods. The results of immunochemical analysis confirm the findings that the resistance to amphiphilic compounds is associated with the outer membrane which limits the access of antimicrobially active molecules to their sites of action in the cytoplasmic membrane. 相似文献
7.
8.
9.
10.