全文获取类型
收费全文 | 1626篇 |
免费 | 152篇 |
国内免费 | 49篇 |
专业分类
耳鼻咽喉 | 12篇 |
儿科学 | 97篇 |
妇产科学 | 19篇 |
基础医学 | 234篇 |
口腔科学 | 49篇 |
临床医学 | 153篇 |
内科学 | 391篇 |
皮肤病学 | 33篇 |
神经病学 | 31篇 |
特种医学 | 199篇 |
外科学 | 188篇 |
综合类 | 98篇 |
预防医学 | 98篇 |
眼科学 | 17篇 |
药学 | 113篇 |
中国医学 | 3篇 |
肿瘤学 | 92篇 |
出版年
2023年 | 17篇 |
2022年 | 23篇 |
2021年 | 31篇 |
2020年 | 23篇 |
2018年 | 25篇 |
2017年 | 46篇 |
2016年 | 42篇 |
2015年 | 36篇 |
2014年 | 68篇 |
2013年 | 74篇 |
2012年 | 34篇 |
2011年 | 36篇 |
2010年 | 77篇 |
2009年 | 74篇 |
2008年 | 36篇 |
2007年 | 79篇 |
2006年 | 47篇 |
2005年 | 41篇 |
2004年 | 32篇 |
2003年 | 25篇 |
2002年 | 20篇 |
2001年 | 38篇 |
2000年 | 24篇 |
1999年 | 20篇 |
1998年 | 82篇 |
1997年 | 65篇 |
1996年 | 61篇 |
1995年 | 54篇 |
1994年 | 48篇 |
1993年 | 43篇 |
1992年 | 15篇 |
1991年 | 24篇 |
1990年 | 32篇 |
1989年 | 37篇 |
1988年 | 39篇 |
1987年 | 30篇 |
1986年 | 34篇 |
1985年 | 39篇 |
1984年 | 19篇 |
1983年 | 16篇 |
1982年 | 13篇 |
1980年 | 12篇 |
1979年 | 18篇 |
1978年 | 15篇 |
1976年 | 17篇 |
1975年 | 17篇 |
1974年 | 19篇 |
1973年 | 14篇 |
1972年 | 13篇 |
1970年 | 13篇 |
排序方式: 共有1827条查询结果,搜索用时 15 毫秒
1.
A M Gonchar A S Kogan A V Troitski? M D Beliaev B N Sokolov S A Usov D G Danilov 《Khirurgiia》1990,(9):69-73
The authors discuss the results of application of proteinase preparations immobilized on a water soluble carrier (Immozymase) and a water insoluble carrier (Profezyme) in the management of ++pyo-necrotic processes of various etiology and localization in 1,059 patients. The wounds were cleansed 1.5-2 times quicker than with the traditional methods of treatment. Immobilized proteinases possessing a prolonged therapeutic effect were found to stimulate the regeneration process. The authors believe the use of Immozymase to be promising in the treatment of purulent foci which are drained with difficulty and in intracavitary administration for treating purulent processes in the thoracic or abdominal cavity. 相似文献
2.
3.
4.
Calciphylaxis – a topical overview 总被引:3,自引:0,他引:3
G Arseculeratne† AT Evans‡ SM Morley† 《Journal of the European Academy of Dermatology and Venereology》2006,20(5):493-502
'Calciphylaxis', a calcification syndrome associated with ischaemic cutaneous necrosis, is acquired naturally in humans in disease states. It is a life and limb-threatening complication, usually observed in patients with renal disease and secondary hyperparathyroidism, but known to occur in the absence of renal or parathyroid disease. The reported mortality rate, which ranges from 60-80%, relates to wound infection, sepsis and organ failure. It is a small-vessel vasculopathy, which is estimated to occur in about 4% of haemodialysis patients. Clinically, violaceous, reticulate areas of cutaneous necrosis and eschar may be evident, particularly in the extremities. In addition to the clinical picture, a raised calcium phosphorous product, an elevated parathyroid hormone level, radiographic evidence of vessel and soft-tissue calcification and the finding of mural calcification affecting small arteries and arterioles on histopathology help to confirm the diagnosis of this entity which generally has a poor prognosis. A high index of suspicion and an active multidisciplinary management approach, with rigorous attention to wound care and prevention of sepsis, are vital in the management of these patients. In this overview, we discuss the pathophysiology, clinical features and associations, risk factors, diagnosis and management issues relating to calciphylaxis. 相似文献
5.
Bastiaan R Klarenbeek Alexander AFA Veenhof Elly SM de Lange Willem A Bemelman Roberto Bergamaschi Piet Heres Antonio M Lacy Wim T van den Broek Donald L van der Peet Miguel A Cuesta 《BMC surgery》2007,7(1):16
Backround
Diverticulosis is a common disease in the western society with an incidence of 33–66%. 10–25% of these patients will develop diverticulitis. In order to prevent a high-risk acute operation it is advised to perform elective sigmoid resection after two episodes of diverticulitis in the elderly patient or after one episode in the younger (< 50 years) patient. Open sigmoid resection is still the gold standard, but laparoscopic colon resections seem to have certain advantages over open procedures. On the other hand, a double blind investigation has never been performed. The Sigma-trial is designed to evaluate the presumed advantages of laparoscopic over open sigmoid resections in patients with symptomatic diverticulitis. 相似文献6.
7.
8.
9.
Effect of porosity on the osteointegration and bone ingrowth of a weight-bearing nickel-titanium bone graft substitute 总被引:8,自引:0,他引:8
Porous nickel-titanium (NiTi) alloy is a promising new material for a bone graft substitute with good strength properties and an elastic modulus closer to that of bone than any other metallic material. The purpose of this study was to evaluate the effect of porosity on the osteointegration of NiTi implants in rat bone. The porosities (average void volume) and the mean pore size (MPS) were 66.1% and 259+/-30 microm (group 1, n=14), 59.2% and 272+/-17 microm (group 2, n=4) and 46.6% and 505+/-136 microm (group 3, n=15), respectively. The implants were implanted in the distal femoral metaphysis of the rats for 30 weeks. The proportional bone-implant contact was best in group 1 (51%) without a significant difference compared to group 3 (39%). Group 2 had lower contact values (29%) than group 1 (p=0.038). Fibrotic tissue within the porous implant was found more often in group 1 than in group 3 (p=0.021), in which 12 samples out of 15 showed no signs of fibrosis. In conclusion, porosity of 66.1% (MPS 259+/-30 microm) showed best bone contact (51%) of the porosities tested here. However, the porosity of 46.6% (MPS 505+/-136 microm) with bone contact of 39% was not significantly inferior in this respect and showed lower incidence of fibrosis within the porous implant. 相似文献
10.