全文获取类型
收费全文 | 759篇 |
免费 | 38篇 |
国内免费 | 8篇 |
专业分类
耳鼻咽喉 | 18篇 |
儿科学 | 47篇 |
妇产科学 | 5篇 |
基础医学 | 97篇 |
口腔科学 | 11篇 |
临床医学 | 68篇 |
内科学 | 125篇 |
皮肤病学 | 23篇 |
神经病学 | 49篇 |
特种医学 | 62篇 |
外科学 | 98篇 |
综合类 | 15篇 |
预防医学 | 113篇 |
眼科学 | 19篇 |
药学 | 28篇 |
中国医学 | 2篇 |
肿瘤学 | 25篇 |
出版年
2022年 | 6篇 |
2021年 | 13篇 |
2020年 | 8篇 |
2019年 | 16篇 |
2018年 | 11篇 |
2017年 | 10篇 |
2016年 | 11篇 |
2015年 | 11篇 |
2014年 | 15篇 |
2013年 | 32篇 |
2012年 | 31篇 |
2011年 | 10篇 |
2010年 | 30篇 |
2009年 | 19篇 |
2008年 | 13篇 |
2007年 | 18篇 |
2006年 | 29篇 |
2005年 | 13篇 |
2004年 | 21篇 |
2003年 | 13篇 |
2002年 | 15篇 |
2001年 | 18篇 |
2000年 | 16篇 |
1999年 | 22篇 |
1998年 | 26篇 |
1997年 | 16篇 |
1996年 | 18篇 |
1995年 | 29篇 |
1994年 | 10篇 |
1993年 | 15篇 |
1992年 | 18篇 |
1991年 | 16篇 |
1990年 | 16篇 |
1989年 | 27篇 |
1988年 | 19篇 |
1987年 | 28篇 |
1986年 | 19篇 |
1985年 | 16篇 |
1984年 | 12篇 |
1982年 | 6篇 |
1981年 | 6篇 |
1980年 | 9篇 |
1979年 | 10篇 |
1978年 | 9篇 |
1977年 | 7篇 |
1974年 | 7篇 |
1973年 | 7篇 |
1972年 | 8篇 |
1968年 | 7篇 |
1966年 | 10篇 |
排序方式: 共有805条查询结果,搜索用时 390 毫秒
1.
Prolidase deficiency is a rare autosomal recessive disorder characterized by cutaneous ulcers, facial dysmorphism, recurrent infections, and intellectual disability. We report a unique case of a 6‐year‐old boy with prolidase deficiency and Crohn's disease who presented with lower extremity ulcers. Cutaneous ulcers due to prolidase deficiency are historically resistant to treatment, and we report success with the novel use of topical tacrolimus. 相似文献
2.
3.
Exposure to high pressure produces neurologic changes in humans which manifest as tremor, EEG changes, and convulsions. Since previous studies have implicated the involvement of the serotoninergic system in these symptoms, it was of interest to study serotonin release at high pressure. Synaptosomes isolated from guinea pig striatum were used to follow serotonin efflux at 68 ATA. The major observation was a decrease in [3H]serotonin release from depolarized striatal synaptosomes at 68 ATA. In view of the role of serotonin as an inhibitory neurotransmitter in this area, the observed decrease in synaptic release leads us to conclude that decreased serotoninergic activity in striatal neurons probably is contributing to the hyperexcitability associated with HPNS. 相似文献
4.
TF Leung WC Tsoi CK Li KW Chik MMK Shing PMP Yuen 《Acta paediatrica (Oslo, Norway : 1992)》1998,87(6):705-777
We describe a 15-y-old girl with Fechtner-like syndrome, who is the first Chinese reported to have this rare syndrome. She presented with left homonymous hemianopia and neuroimaging revealed haemorrhage in both parietal and occipital lobes. Peripheral blood smear showed macrothrombocytopenia and intracytoplasmic inclusion bodies inside leucocytes. Thrombocytopenia and proteinuria responded to intravenous immunoglobulin and pulsed methylprednisolone. This case illustrates that life-threatening haemorrhage can occur in patients with Fechtner syndrome. Although there was no effective treatment reported in the literature, high dose steroid and immunoglobulin seemed to be useful in our patient. Our patient also had nephritic-nephrotic syndrome with renal insufficiency, which is unusual in adolescent female patients. 相似文献
5.
Theodore Colton Laurence Freedman Tony Johnson David MaChin 《Statistics in medicine》1989,8(6):639-639
6.
7.
8.
9.
10.
Bersinger NA; Brandenberger A; Berger E; Baumann CK; Birkhauser MH 《Human reproduction (Oxford, England)》1998,13(7):1962-1967
We have previously observed the repeated presence of low but detectable
amounts of the trophoblast marker pregnancy-specific beta1-glycoprotein
(SP1) in the serum of some women undergoing in-vitro fertilization (IVF)
treatment around the time of oocyte retrieval. The occurrence of these
signals seemed to be restricted to a defined group of patients which also
showed a lower pregnancy success rate in a preliminary study. To test our
hypothesis we have analysed 173 consecutive cycles leading to an embryo
transfer. Fifty-four cycles (31%) had a serum SP1 level of at least 0.1
ng/ml between days embryo transfer -5 and embryo transfer (group A). Five
pregnancies were obtained in this group (pregnancy rate = 9.3%), while in
group B, defined by the absence of detectable SP1 before embryo transfer
(119 cycles), 36 ongoing pregnancies were achieved (30.3%). Ten of the 41
pregnancies were achieved in 33 first-time non-pregnant patients undergoing
further attempts during the study period. Again the pregnancy rate was
higher in the first-time group B women (9/23 versus 1/10 for group A).
Patients tended to remain in their groups A or B, the latter being
associated with a better immediate as well as subsequent chance for
pregnancy. Group A cycles had a significantly lower endometrial thickness
two days before oocyte retrieval than group B (P = 0.0011). We postulate
that the presence of an unknown, maternal and progesterone- or follicle
stimulating hormone-independent factor in some patients could stimulate
tonic ectopic SP1 synthesis and at the same time negatively influence
endometrial development.
相似文献