全文获取类型
收费全文 | 4490篇 |
免费 | 268篇 |
国内免费 | 12篇 |
专业分类
耳鼻咽喉 | 29篇 |
儿科学 | 190篇 |
妇产科学 | 66篇 |
基础医学 | 532篇 |
口腔科学 | 43篇 |
临床医学 | 308篇 |
内科学 | 1045篇 |
皮肤病学 | 147篇 |
神经病学 | 202篇 |
特种医学 | 103篇 |
外科学 | 446篇 |
综合类 | 537篇 |
一般理论 | 3篇 |
预防医学 | 279篇 |
眼科学 | 68篇 |
药学 | 386篇 |
1篇 | |
中国医学 | 21篇 |
肿瘤学 | 364篇 |
出版年
2022年 | 46篇 |
2021年 | 125篇 |
2020年 | 53篇 |
2019年 | 69篇 |
2018年 | 88篇 |
2017年 | 61篇 |
2016年 | 80篇 |
2015年 | 126篇 |
2014年 | 139篇 |
2013年 | 150篇 |
2012年 | 190篇 |
2011年 | 255篇 |
2010年 | 194篇 |
2009年 | 144篇 |
2008年 | 183篇 |
2007年 | 195篇 |
2006年 | 186篇 |
2005年 | 193篇 |
2004年 | 221篇 |
2003年 | 133篇 |
2002年 | 114篇 |
2001年 | 124篇 |
2000年 | 103篇 |
1999年 | 97篇 |
1998年 | 43篇 |
1997年 | 62篇 |
1996年 | 48篇 |
1995年 | 35篇 |
1994年 | 37篇 |
1992年 | 76篇 |
1991年 | 64篇 |
1990年 | 43篇 |
1989年 | 57篇 |
1988年 | 60篇 |
1987年 | 48篇 |
1986年 | 61篇 |
1985年 | 63篇 |
1984年 | 56篇 |
1983年 | 38篇 |
1982年 | 41篇 |
1979年 | 48篇 |
1978年 | 52篇 |
1977年 | 36篇 |
1976年 | 39篇 |
1974年 | 32篇 |
1973年 | 40篇 |
1972年 | 31篇 |
1971年 | 40篇 |
1970年 | 42篇 |
1969年 | 30篇 |
排序方式: 共有4770条查询结果,搜索用时 31 毫秒
1.
2.
3.
4.
MUAMMER SEYHAN BAAK KANDI COKUN HÜLYA SALAM HAMDI ÖZCAN YELDA KARINCAOLU 《Pediatrics international》2006,48(6):525-530
BACKGROUND: The present study was aimed to define the gender ratio, familial occurrence, age of onset, precipitating factors, clinical types, nail and joint involvement of psoriasis in childhood and adolescence in Turkey. METHODS: A total of 61 children with psoriasis under 18 years old were evaluated retrospectively, for age, gender, age of disease onset, family history, concomitant disease, the clinical type of psoriasis, clinical localization, nail and joint involvement and treatment modalities. RESULTS: Of the patients, 23 (37.70%) were boys and 38 (62.30%) were girls. Mean age was 9.28 +/- 4.02 years in girls and 11.18 +/- 3.85 years in boys (9.96 +/- 4.03 years in all children). Mean age at the onset of the disease was 6.81 +/- 4.11 years in girls and 7.03 +/- 4.28 years in boys (6.89 +/- 4.14 years in all patients). In 14 (23%) cases, a positive family history was detected. The most frequent probable triggering factors were upper respiratory tract infections (14.8%) and positive throat culture for A group ss-hemolytic streptococcus (21.3%). Frequency of emotional stress and psychiatric morbidity were 54% and 9.8%, respectively. The most frequent localizations at onset were trunk (44.3%), extremities (54.0%), and scalp (36.0%). Three children (4.9%) had a history of dissemination from psoriatic diaper rash. In total, 51 (83.6%) patients presented with psoriasis vulgaris, eight (13.1%) with generalized pustular psoriasis, and the remaining two (3.3%) with erythrodermic psoriasis. CONCLUSION: The incidence of psoriasis among dermatological patients in childhood and adolescence was 3.8%. The disease tends to appear earlier in girls than boys. The authors suggested that stress and upper respiratory infections are the most important triggering factors in childhood and adolescence psoriasis. 相似文献
5.
V Aerra M Kuduvalli AN Moloto AK Srinivasan AD Grayson BM Fabri AY Oo 《Journal of cardiothoracic surgery》2006,1(1):6-5
Background
Atrial fibrillation can occur in up to 40% of patients undergoing coronary surgery. 相似文献6.
Daniel D. Billadeau Subrha Chatterjee Patricia Bramati Raghavakaimal Sreekumar Vijay Shah Karen Hedin Raul Urrutia 《Journal of gastrointestinal cancer》2006,37(4):110-119
CXCL12 and its receptor, CXCR4, are emerging as promising targets for modulating growth, angiogenesis, and metastasis in several human cancers. Indeed, blocking the receptor is sufficient to prevent metastasis and angiogenesis in experimental breast cancer xenografts. Recently, the biological effect of the CXCR4 in pancreatic cancer, one of the most deadly neoplastic diseases, has been reported. However, the molecular mechanism by which CXCR4 contributes to these properties is not completely understood. In this paper, we characterize the signaling pathways activated by CXCR4 in pancreatic cancer. We show that after CXCR4 activation, EGFR becomes tyrosine phosphorylated, and the kinase activity of this receptor, together with the activation of MMPs, Src, and PI3-Kinase, is required for CXCR4-mediated ERK activation. Analysis of this cascade in pancreatic cancer cells revealed that the ERK-mediated pathway regulates genes involved in angiogenesis, such as VEGF, CD44, HIF1α, and IL-8. Furthermore, ERK blockage inhibits the migration and tube formation of endothelial cells induced by CXCL12. Considering that inhibitors for several components of this pathway, including CXCR4 itself, are at different stages of clinical trials, this study provides theoretical justification for the clinical testing of these drugs in pancreatic cancer, thus extending the list of potential targets for treating this dismal disease. 相似文献
7.
S. K. Das Chandan Kumar Ghosal B. K. Roychaudhuri P. R. Chatterjee 《Indian journal of otolaryngology and head and neck surgery》1991,43(2):80-81
Haemangioma of the maxillary sinus is rare. Clinical diagnosis is of utmost importance for its operative treatment and prevention of hazards. A case is reported for its rarity and some unusual features. 相似文献
8.
9.
National Programme of Research in Human Reproduction S.K. Banerjee R. Baveja R.V. Bhatt A. Chatterjee S.D. Choudhury B. Coyaji A.D. Engineer M.P. Gogoi V. Hingorani K. Lal M. Kochhar U. Krishna P. Misra F.S. Philips R. Rajan P.C. Sen Gupta K. Zaveri S. Datey S. Gupta S. Mehta N.C. Saxena B.N. Saxena 《Contraception》1986,34(6):573-582
The return of fertility following discontinuation of norethisterone oenanthate (NET EN) 200 mg injectable contraceptive after use for a minimum period of six months or more was studied in 69 women who discontinued the method for planning pregnancy. Former users of copper intra-uterine device (CuT 200) were enrolled as a control group. Another 161 women who had discontinued NET EN due to other reasons (e.g. amenorrhoea, excessive bleeding or personal reasons) were also studied for return of fertility after ensuring that they were not using any other method of contraception and were exposed to the risk of pregnancy. The subjects from both groups were followed for a period of one year. The cumulative conception rates at one year were 72.5 and 83.6 per 100 subjects for ex-NET EN and ex-CuT 200 users who had discontinued the method for planning pregnancy and this difference was not statistically significant (P > 0.05). The median time for conception for ex-NET EN users was 7.8 months as compared to 3.7 months in ex-CuT 200 users but the cumulative conception rates at the end of one year show that future return of fertility in NET EN users does not appear to be adversely affected.
In 51 subjects who had discontinued NET EN due to amenorrhoea, the return of fertility was predictably slower and less. The return of fertility in subjects who discontinued NET EN for other reasons (e.g. excessive bleeding and other personal reasons) was similar to ex-NET EN and ex-CuT 200 users. 相似文献
10.