全文获取类型
收费全文 | 118篇 |
免费 | 8篇 |
专业分类
儿科学 | 3篇 |
妇产科学 | 3篇 |
基础医学 | 13篇 |
临床医学 | 9篇 |
内科学 | 23篇 |
皮肤病学 | 2篇 |
神经病学 | 5篇 |
特种医学 | 1篇 |
外科学 | 15篇 |
综合类 | 1篇 |
预防医学 | 11篇 |
眼科学 | 20篇 |
药学 | 11篇 |
肿瘤学 | 9篇 |
出版年
2024年 | 1篇 |
2023年 | 1篇 |
2022年 | 1篇 |
2021年 | 6篇 |
2020年 | 5篇 |
2019年 | 2篇 |
2018年 | 7篇 |
2017年 | 7篇 |
2016年 | 6篇 |
2015年 | 9篇 |
2014年 | 10篇 |
2013年 | 6篇 |
2012年 | 17篇 |
2011年 | 15篇 |
2010年 | 6篇 |
2009年 | 5篇 |
2008年 | 3篇 |
2007年 | 4篇 |
2006年 | 2篇 |
2005年 | 2篇 |
2004年 | 3篇 |
2003年 | 4篇 |
2002年 | 1篇 |
2001年 | 1篇 |
1990年 | 1篇 |
1984年 | 1篇 |
排序方式: 共有126条查询结果,搜索用时 31 毫秒
1.
2.
3.
Carla Lanca Li-Lian Foo Marcus Ang Chuen-Seng Tan Biten Kathrani Hla Myint Htoon Donald Tan Quan V. Hoang Noel Brennan Seang-Mei Saw Charumathi Sabanayagam 《Investigative ophthalmology & visual science》2021,62(4)
PurposeThe purpose of this study was to evaluate the association of childhood progression of spherical equivalent (SE) with high myopia (HM) in teenagers in the Singapore Cohort of Risk factors for Myopia (SCORM).MethodsWe included 928 SCORM children followed over a mean follow-up of 6.9 ± 1.0 years from baseline (6–11 years old) until their teenage years (12–19 years old). Cycloplegic autorefraction and axial length (AL) measurements were performed yearly. The outcomes in teenagers were HM (SE ≤ −5 diopter [D)], AL ≥ 25 mm, SE and AL. Three-year SE and AL progression in childhood and baseline SE and AL with outcomes were evaluated using multivariable logistic or linear regression models, with predictive performance of risk factors assessed using the area under the curve (AUC).ResultsAt the last visit, 9.8% of teenagers developed HM and 22.7% developed AL ≥ 25 mm. In multivariate regression analyses, every −0.3 D/year increase in 3-year SE progression and every 0.2 mm/year increase in 3-year AL progression were associated with a −1.14 D greater teenage SE and 0.52 mm greater teenage AL (P values < 0.001). The AUC (95% confidence interval [CI]) of a combination of 3-year SE progression and baseline SE for teenage HM was 0.97 (95% CI = 0.95 – 0.98). The AUC of 3-year AL progression and baseline AL for teenage AL ≥ 25 mm was 0.91 (95% CI = 0.89 – 0.94).ConclusionsThree-year myopia progression in childhood combined with baseline SE or AL were good predictors of teenage HM. Clinicians may use this combination of factors to guide timing of interventions, potentially reducing the risk of HM later in life. 相似文献
4.
5.
Epizootic hemorrhagic disease virus (EHDV) was isolated from a pregnant cow in Indiana, USA, exhibiting excessive salivation, pyrexia and abortion. VP2, VP5, and VP7 sequences of the isolated bovine EHDV showed 97.7, 97.4, and 97.9 % identity to a serotype 2 reference virus. Bovine EHDV was closely related (>99.9 %) to white tailed deer (WTD) EHDV collected from Iowa in 2013 and showed less than 2.1 % divergence from EHDV collected from WTD across the USA in 2013. The high degree of sequence identity between bovine and WTD EHDV isolates demonstrates that similar viruses concurrently circulate in both species and suggests possible further incursions into bovines. 相似文献
6.
Aswin kumar Anbalagan Shivam Gupta Mayur Chaudhary Rishi Ranjan Kumar Yu-Lun Chueh Nyan-Hwa Tai Chih-Hao Lee 《RSC advances》2021,11(38):23345
Correction for ‘Consequences of gamma-ray irradiation on structural and electronic properties of PEDOT:PSS polymer in air and vacuum environments’ by Aswin kumar Anbalagan et al., RSC Adv., 2021, 11, 20752–20759, DOI: 10.1039/D1RA03463D.The authors regret that incorrect details were given for ref. 18. The correct version of ref. 18 is given here as ref. 1.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers. 相似文献
7.
Diogo Ribeiro Ana Rita Nunes Michael Gliksberg Savani Anbalagan Gil Levkowitz Rui F. Oliveira 《Journal of neuroendocrinology》2020,32(4)
Sociality is a complex phenomenon that involves the individual´s motivation to approach their conspecifics, along with social cognitive functions that enable individuals to interact and survive. The nonapeptide oxytocin (OXT) is known to regulate sociality in many species. However, the role of OXT in specific aspects of sociality is still not well understood. In the present study, we investigated the contribution of the OXT receptor (OXTR) signalling in two different aspects of zebrafish social behaviour: social preference, by measuring their motivation to approach a shoal of conspecifics, and social recognition, by measuring their ability to discriminate between a novel and familiar fish, using a mutant zebrafish lacking a functional OXTR. Although oxtr mutant zebrafish displayed normal attraction to a shoal of conspecifics, they exhibited reduced social recognition. We further investigated whether this effect would be social‐domain specific by replacing conspecific fish by objects. Although no differences were observed in object approach, oxtr mutant fish also exhibited impaired object recognition. Our findings suggest that OXTR signalling regulates a more general memory recognition of familiar vs novel entities, not only in social but also in a non‐social domain, in zebrafish. 相似文献
8.
Charumathi Dasarathan Prashant Vaijyanath Kothurathu Mammem Cherian 《Indian Journal of Thoracic and Cardiovascular Surgery》2010,26(3):207-209
An infected tricuspid valve was successfully replaced with a fresh antibiotic treated Homovital mitral homograft procured
from recipient cardiectomy specimen of simultaneous cardiac transplant in our unit. This operation seems superior to valvectomy
alone or the use of a stented prosthesis in terms of hemodynamics and resistance to infection. 相似文献
9.
Sivakumar R Anbalagan N Gunasekaran V Leonard JT 《Biological & pharmaceutical bulletin》2003,26(10):1407-1411
The synthesis and pharmacological evaluation of novel 1-substituted-1,2-dihydro-pyridazine-3,6-diones (4a--l, 5a--j) as potential anticonvulsant agents are described. The compounds were tested in vivo for the anticonvulsant activity. The compound which have maximum protection against MES induced seizures is 1-[3-(2-aminophenylamino)-2-hydroxypropyl)-1,2-dihydro-pyridazine-3,6-dione 4h (ED(50)=44.7 mg x kg(-1) i.p.) 1-[2-hydroxy-3-piperazin1-yl-propyl)-1,2-dihydro-pyridazine-3,6-dione 4c (ED(50)=72 mg x kg(-1) i.p.) and 1-[2-hydroxy-3-imidazol-1-yl-propyl)-1,2-dihydro-pyridazine-3,6-dione 4d (ED(50)=79 mg x kg(-1) i.p.) were also found to have maximum protection against MES induced seizures. Whereas all these compounds failed to protect the animals from subcutaneous pentylenetetrazole (Metrozol) seizure threshold test (sc-Met). 相似文献
10.