全文获取类型
收费全文 | 2370727篇 |
免费 | 177608篇 |
国内免费 | 5522篇 |
专业分类
耳鼻咽喉 | 32233篇 |
儿科学 | 76120篇 |
妇产科学 | 62961篇 |
基础医学 | 351400篇 |
口腔科学 | 64069篇 |
临床医学 | 214758篇 |
内科学 | 460577篇 |
皮肤病学 | 51961篇 |
神经病学 | 186496篇 |
特种医学 | 88939篇 |
外国民族医学 | 510篇 |
外科学 | 356499篇 |
综合类 | 51837篇 |
现状与发展 | 21篇 |
一般理论 | 852篇 |
预防医学 | 184040篇 |
眼科学 | 54965篇 |
药学 | 177753篇 |
40篇 | |
中国医学 | 6057篇 |
肿瘤学 | 131769篇 |
出版年
2021年 | 20538篇 |
2019年 | 20479篇 |
2018年 | 28076篇 |
2017年 | 21234篇 |
2016年 | 23573篇 |
2015年 | 26955篇 |
2014年 | 37729篇 |
2013年 | 55219篇 |
2012年 | 76594篇 |
2011年 | 81549篇 |
2010年 | 48373篇 |
2009年 | 45595篇 |
2008年 | 75919篇 |
2007年 | 80868篇 |
2006年 | 81617篇 |
2005年 | 79237篇 |
2004年 | 75195篇 |
2003年 | 72429篇 |
2002年 | 70052篇 |
2001年 | 109284篇 |
2000年 | 111995篇 |
1999年 | 94120篇 |
1998年 | 27483篇 |
1997年 | 24115篇 |
1996年 | 24442篇 |
1995年 | 23061篇 |
1994年 | 21165篇 |
1993年 | 19868篇 |
1992年 | 72194篇 |
1991年 | 70215篇 |
1990年 | 68521篇 |
1989年 | 65786篇 |
1988年 | 60434篇 |
1987年 | 59207篇 |
1986年 | 55302篇 |
1985年 | 53064篇 |
1984年 | 39344篇 |
1983年 | 33420篇 |
1982年 | 19877篇 |
1979年 | 35878篇 |
1978年 | 25651篇 |
1977年 | 21230篇 |
1976年 | 20332篇 |
1975年 | 21818篇 |
1974年 | 26148篇 |
1973年 | 24802篇 |
1972年 | 23200篇 |
1971年 | 22037篇 |
1970年 | 20247篇 |
1969年 | 19315篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
Hassen Lena M. Albarrak Rana A. Albahlal Reem A. Alsaqabi Dimah K. Hassen Ikhlass M. Daghestani Maha H. Alqurtas Eman M. Alkhalaf Abdulaziz T. Bedaiwi Mohammed K. Omair Mohammed A. Almaghlouth Ibrahim A. 《Quality of life research》2022,31(11):3229-3239
Quality of Life Research - The COVID-19 pandemic might add to the stressors experienced by people living with rheumatic diseases. This study aimed to examine rheumatic patients’ functional... 相似文献
2.
Ecotoxicology - Soil heavy metal pollution evaluations are a necessary measure for mine ecological control projects. In this study, the heavy metals Pb, Zn and Cd were studied in mining areas,... 相似文献
3.
Molnár B. Aroca S. Dobos A. Orbán K. Szabó J. Windisch P. Stähli A. Sculean A. 《Clinical oral investigations》2022,26(12):7135-7142
Clinical Oral Investigations - To evaluate t he long-term outcomes following treatment of RT 1 multiple adjacent gingival recessions (MAGR) using the modified coronally advanced tunnel (MCAT) with... 相似文献
4.
Background: Breast cancer (BC) is the most common malignant tumor in women, and its morbidity and mortality are
increasing each year, due to the lack of specific clinical symptoms in the early stage of BC, and the lack of diagnostic
methods for early breast cancer. Therefore, identifying an effective diagnostic method for early BC has become urgent.
Materials and Methods: Breast lesions with a histological diagnosis that were examined by ultrasonic elastography
(UE) in our department from June 2020 to December 2021 were reviewed. qRT-PCR was performed to measure
the expression levels of miR-144-5p and miR-26b-5p in the plasma of patients with BC. The receiver operating characteristics (ROC) curve and area under the curve (AUC) were used to investigate the potential diagnostic value of miR-
144-5p, miR-26b-5p and the elastographic score in BC. Results: The ultrasonic elastography score(UES) was found to
be significantly upregulated in BC compared with that in benign breast lesions, and the AUC, sensitivity and specificity
were 0.809, 0.717 and 0.806 for distinguishing BC from benign breast lesions, respectively. miR-144-5p and miR-26b-
5p were found to be upregulated in the plasma of BC patients, and miR-144-5p+miR-26b-5p had 0.781 sensitivity and
0.780 specificity for the diagnosis of BC. Furthermore, we found that the diagnostic performance of miR-144-5p and
miR-26b-5p combined with UES for BC had 0.913 sensitivity and 0.890 specificity. Conclusions: The combination of
plasma miR-144-5p, miR-26b-5p and UES has a very high clinical application value for the early detection of BC. 相似文献
5.
6.
7.
Lesmana Cosmas Rinaldi Adithya Paramitha Maria Satya Gani Rino A. Lesmana Laurentius A. 《Journal of Medical Ultrasonics》2022,49(3):359-370
Journal of Medical Ultrasonics - Chronic liver disease is still a major problem because disease progression will ultimately lead to liver cirrhosis. Portal hypertension is the hallmark in advanced... 相似文献
8.
痛情绪是指因疼痛引发的情绪和情感体验,是疾病过程中最常见的一种情绪。痛情绪相关神经机制非常复杂,但主要与单胺类神经递质、神经肽和某些神经环路有关,笔者将结合目前研究现状分别从以上两方面展开,就痛情绪相关单胺类神经递质和神经肽在受体分类、脑区通路、共疾病以及各神经递质之间的联系和痛情绪相关神经环路中各个蛋白的作用机制等方面进行探讨。 相似文献
9.
10.
Wuteng Cao Huabin Hu Jiao Li Qianyu Wu Lishuo Shi Biao Li Jie Zhou Xinhua Wang Junhong Chen Chao Wang Huaiming Wang Weihao Deng Yan Huang Yanhong Deng 《International journal of cancer. Journal international du cancer》2023,153(11):1894-1903
Neoadjuvant programmed cell death protein 1 (PD-1) blockade exhibits promising efficacy in patients with mismatch repair deficient (dMMR) colorectal cancer (CRC). However, discrepancies between radiological and histological findings have been reported in the PICC phase II trial (NCT 03926338). Therefore, we strived to discern radiological features associated with pathological complete response (pCR) based on computed tomography (CT) images. Data were obtained from the PICC trial that included 36 tumors from 34 locally advanced dMMR CRC patients, who received neoadjuvant PD-1 blockade for 3 months. Among the 36 tumors, 28 (77.8%) tumors achieved pCR. There were no statistically significant differences in tumor longitudinal diameter, the percentage change in tumor longitudinal diameter from baseline, primary tumor sidedness, clinical stage, extramural venous invasion status, intratumoral calcification, peritumoral fat infiltration, intestinal fistula and tumor necrosis between the pCR and non-pCR tumors. Otherwise, tumors with pCR had smaller posttreatment tumor maximum thickness (median: 10 mm vs 13 mm, P = .004) and higher percentage decrease in tumor maximum thickness from baseline (52.9% vs 21.6%, P = .005) compared to non-pCR tumors. Additionally, a higher proportion of the absence of vascular sign (P = .003, odds ratio [OR] = 25.870 [95% CI, 1.357-493.110]), nodular sign (P < .001, OR = 189.000 [95% CI, 10.464-3413.803]) and extramural enhancement sign (P = .003, OR = 21.667 [2.848-164.830]) was observed in tumors with pCR. In conclusion, these CT-defined radiological features may have the potential to serve as valuable tools for clinicians in identifying patients who have achieved pCR after neoadjuvant PD-1 blockade, particularly in individuals who are willing to adopt a watch-and-wait strategy. 相似文献