全文获取类型
收费全文 | 557篇 |
免费 | 19篇 |
国内免费 | 21篇 |
专业分类
耳鼻咽喉 | 2篇 |
儿科学 | 27篇 |
妇产科学 | 5篇 |
基础医学 | 73篇 |
口腔科学 | 30篇 |
临床医学 | 34篇 |
内科学 | 103篇 |
皮肤病学 | 14篇 |
神经病学 | 8篇 |
特种医学 | 95篇 |
外科学 | 63篇 |
综合类 | 49篇 |
预防医学 | 26篇 |
眼科学 | 6篇 |
药学 | 48篇 |
肿瘤学 | 14篇 |
出版年
2022年 | 4篇 |
2021年 | 2篇 |
2020年 | 4篇 |
2019年 | 5篇 |
2018年 | 9篇 |
2017年 | 4篇 |
2016年 | 2篇 |
2015年 | 8篇 |
2014年 | 8篇 |
2013年 | 19篇 |
2012年 | 7篇 |
2011年 | 12篇 |
2010年 | 23篇 |
2009年 | 26篇 |
2008年 | 10篇 |
2007年 | 31篇 |
2006年 | 40篇 |
2005年 | 11篇 |
2004年 | 25篇 |
2003年 | 15篇 |
2002年 | 8篇 |
2001年 | 9篇 |
2000年 | 9篇 |
1999年 | 13篇 |
1998年 | 27篇 |
1997年 | 32篇 |
1996年 | 39篇 |
1995年 | 22篇 |
1994年 | 13篇 |
1993年 | 20篇 |
1992年 | 7篇 |
1991年 | 6篇 |
1990年 | 3篇 |
1989年 | 21篇 |
1988年 | 11篇 |
1987年 | 13篇 |
1986年 | 11篇 |
1985年 | 10篇 |
1984年 | 9篇 |
1983年 | 5篇 |
1982年 | 5篇 |
1981年 | 5篇 |
1980年 | 10篇 |
1979年 | 3篇 |
1978年 | 3篇 |
1977年 | 5篇 |
1976年 | 5篇 |
1975年 | 5篇 |
1962年 | 1篇 |
1935年 | 1篇 |
排序方式: 共有597条查询结果,搜索用时 31 毫秒
1.
Coronary artery bypass grafts: visualization with MR imaging 总被引:1,自引:0,他引:1
2.
G. Burastero N. Sessarego G. Grappiolo C. Castellazzo S. Castello A. Pitto G. Cittadini M. Podesta G. Bovio M. Peresi E. Fulcheri F. Frassoni L. Spotorno 《Journal of orthopaedics and traumatology》2007,8(1):49-54
Mesenchymal stem cells (MSC), easily culture-expanded from bone marrow, can significantly enhance bone defect healing. Several
proteins, such as the bone morphogenetic proteins (BMPs) and in particular BMP-7, are involved in bone formation in vitro
and in vivo. In this preclinical study, we evaluated if the association of human MSC (hMSC) with BMP-7 had synergic action
on bone healing. Rat femoral defects (n=12) were treated with: autoclaved bone and mononucleated cells (MNC) as control group
G1; bone and hMSC, group G2; bone with BMP-7, group G3; bone and hMSC plus BMP-7, group G4. Defect regeneration was evaluated
with plain radiographs after 2, 4, 8 and 12 weeks and with histological analysis. We observed organized trabeculae bridging
between the osteotomic ends of the host bone in rats treated with the association of hMSC and rhBMP-7. These trabeculae, formed
by a core of devitalized tissue surrounded by osteoblasts, osteocytes and osteoclasts, were continuous with a cortical-like
structure of bony tissue. Such new bone formation of the group treated with the association of hMSC and rhBMP-7 (G4) was clearly
superior compared to rats treated with rhBMP-7 (G2) or hMSC (G3) alone, as shown by radiographic analysis and histological
study. The present study suggests that the association of hMSC and BMP-7 is more effective than hMSC or BMP-7 alone in the
healing of femoral defects in rats. Further studies with larger samples are required to confirm these results and to evaluate
the best dosage. 相似文献
3.
4.
5.
6.
7.
Genotype-phenotype correlation for nucleotide substitutions in the IgII- IgIII linker of FGFR2 总被引:6,自引:3,他引:3
8.
9.
10.
Localization of a gene for otosclerosis to chromosome 15q25-q26 总被引:5,自引:0,他引:5
Tomek MS; Brown MR; Mani SR; Ramesh A; Srisailapathy CR; Coucke P; Zbar RI; Bell AM; McGuirt WT; Fukushima K; Willems PJ; Van Camp G; Smith RJ 《Human molecular genetics》1998,7(2):285-290
Among white adults otosclerosis is the single most common cause of hearing
impairment. Although the genetics of this disease are controversial, the
majority of studies indicate autosomal dominant inheritance with reduced
penetrance. We studied a large multi- generational family in which
otosclerosis has been inherited in an autosomal dominant pattern. Five of16
affected persons have surgically confirmed otosclerosis; the remaining nine
have a conductive hearing loss but have not undergone corrective surgery.
To locate the disease- causing gene we completed genetic linkage analysis
using short tandem repeat polymorphisms (STRPs) distributed over the entire
genome. Multipoint linkage analysis showed that only one genomic region, on
chromosome 15q, generated a lod score >2.0. Additional STRPs were typed
in this area, resulting in a lod score of 3.4. STRPs FES (centromeric) and
D15S657 (telomeric) flank the 14. 5 cM region that contains an otosclerosis
gene.
相似文献