全文获取类型
收费全文 | 9639篇 |
免费 | 819篇 |
国内免费 | 28篇 |
专业分类
耳鼻咽喉 | 111篇 |
儿科学 | 334篇 |
妇产科学 | 185篇 |
基础医学 | 1264篇 |
口腔科学 | 314篇 |
临床医学 | 938篇 |
内科学 | 1649篇 |
皮肤病学 | 125篇 |
神经病学 | 926篇 |
特种医学 | 397篇 |
外科学 | 1622篇 |
综合类 | 148篇 |
一般理论 | 4篇 |
预防医学 | 798篇 |
眼科学 | 169篇 |
药学 | 506篇 |
中国医学 | 8篇 |
肿瘤学 | 988篇 |
出版年
2021年 | 110篇 |
2020年 | 83篇 |
2019年 | 122篇 |
2018年 | 137篇 |
2017年 | 90篇 |
2016年 | 146篇 |
2015年 | 119篇 |
2014年 | 230篇 |
2013年 | 285篇 |
2012年 | 417篇 |
2011年 | 421篇 |
2010年 | 220篇 |
2009年 | 215篇 |
2008年 | 366篇 |
2007年 | 402篇 |
2006年 | 407篇 |
2005年 | 371篇 |
2004年 | 370篇 |
2003年 | 354篇 |
2002年 | 373篇 |
2001年 | 297篇 |
2000年 | 318篇 |
1999年 | 304篇 |
1998年 | 123篇 |
1997年 | 105篇 |
1996年 | 75篇 |
1995年 | 98篇 |
1994年 | 82篇 |
1993年 | 72篇 |
1992年 | 249篇 |
1991年 | 260篇 |
1990年 | 229篇 |
1989年 | 234篇 |
1988年 | 208篇 |
1987年 | 254篇 |
1986年 | 214篇 |
1985年 | 188篇 |
1984年 | 156篇 |
1983年 | 129篇 |
1982年 | 79篇 |
1981年 | 87篇 |
1979年 | 133篇 |
1978年 | 98篇 |
1977年 | 86篇 |
1976年 | 76篇 |
1974年 | 79篇 |
1973年 | 86篇 |
1972年 | 82篇 |
1971年 | 77篇 |
1970年 | 71篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
Itay Zmora Yonit Wiener-Well Evan Avraham Alpert 《The American journal of emergency medicine》2019,37(5):1006.e5-1006.e7
Background
Purulent bacterial pericarditis is a rare and potentially fatal disease. The course may be fulminant, and the presentation may pose a diagnostic challenge.Case report
An otherwise healthy 75-year-old male was brought to the emergency department in a state of general deterioration, confusion, and shock. Bedside ultrasound showed a significant pericardial effusion. His condition quickly deteriorated and the resuscitation included emergent bedside pericardiocentesis. The drainage was purulent and later cultures grew out Streptococcus pneumoniae.Why should an emergency physician be aware of this?
Purulent pericarditis is extremely rare but should be considered in the patient with a fulminant infectious process (particularly pneumonia) and signs of pericardial effusion. Treatment should include appropriate antibiotics and early drainage. 相似文献3.
W. Do T. Elzerman R. de Bree A. Rosenberg T. Forouzanfar E.M. Van Cann 《International journal of oral and maxillofacial surgery》2021,50(5):591-597
The aim of this study was to analyse the effect of body mass index (BMI), both low and high values, on the perioperative complication rate in patients with oral squamous cell carcinoma (OSCC). The medical records of 259 patients operated between 2014 and 2017 for OSCC were reviewed. Univariate and multivariate analyses were performed. Sixty of the 259 patients developed 87 complications. Low or high BMI was not associated with the perioperative complication rate. A longer operating time and increased blood loss were associated with a higher perioperative complication rate and higher Clavien–Dindo grade. Low BMI, American Society of Anesthesiologists score 2 and 3, a longer operating time, and increased blood loss were associated with a longer hospital stay. Low BMI was associated with a longer hospital stay. Neither low nor high BMI was associated with the perioperative complication rate. A longer operating time and increased blood loss were associated with a higher perioperative complication rate and higher Clavien–Dindo grade. 相似文献
4.
5.
Hydration and Cognitive Function in Children 总被引:3,自引:0,他引:3
Kristen E. D'Anci PhD Florence Constant MD PhD Irwin H. Rosenberg MD 《Nutrition reviews》2006,64(10):457-464
Adequate fluid intake is critical for survival. While adults are at liberty to drink fluids as wanted, children and infants are dependent upon caregivers for food and fluid. Children are at greater risk for dehydration than adults due to their higher surface-to-mass ratio. Additionally, children have different thirst sensitivities and body cooling mechanisms than adults. Children differ from adults in total body water content, and boys and girls differ in body water content with maturation. Research in young adults shows that mild dehydration corresponding to only 1% to 2% of body weight loss can lead to significant impairment in cognitive function. Dehydration in infants is associated with confusion, irritability, and lethargy; in children, it may produce decrements in cognitive performance. 相似文献
6.
7.
Ophira Salomon Joseph Moisseiev Tamara Vilganski Rima Dardik Shimon Kurtz Eva Shpringer David M Steinberg Nurit Rosenberg 《Blood coagulation & fibrinolysis》2006,17(6):485-488
To determine whether polymorphisms of platelet surface glycoprotein associated with arterial thrombosis are risk factors for branch retinal vein occlusion. A case-control study in which 69 patients with branch retinal vein occlusion and 147 controls who attended the eye clinic for nonvascular complications participated. DNA was extracted from whole blood and analyzed for genotyping of platelet glycoprotein polymorphisms by polymerase chain reactions and specific restricted enzymes. No relationship was found between the four platelet glycoprotein polymorphisms i.e. GPIa C807T, VNTR and Kozak of glycoprotein Ibalpha, the HPA-1 of glycoprotein IIIa and the occurrence of branch retinal vein occlusion. The HPA-2 polymorphism was found in 18 out 60 (30%) patients with branch retinal vein occlusion in comparison with 27 out 142 (19%) of controls, with an estimated odds ratio of 1.8 (95% confidence interval, 0.91-3.65). The four platelet glycoprotein polymorphisms are not risk factors for branch retinal vein occlusion and therefore it seems unnecessary to screen those patients for it. A larger study is required, however, to determine whether HPA-2 is a novel risk factor for branch retinal vein occlusion. 相似文献
8.
Pamela D Reiter Adam A Rosenberg Robert Valuck Kathryn Novak 《Journal of perinatology》2005,25(2):125-129
OBJECTIVE: To determine the effectiveness of a 10-day subcutaneous erythropoietin (rHuEpo) course of 300 units per kg per dose plus oral iron compared to oral iron alone in anemic infants during their convalescent phase of illness. STUDY DESIGN: Prospective, randomized trial performed at a 40-bed, teaching, referral, level III, neonatal intensive care unit. Infants with a gestational age at birth of less than 32 weeks, hematocrit of less than or equal to 28% with a corrected reticulocyte count of less than or equal to 5%, postconceptual age of less than 48 weeks or 5 months chronological age, and a diagnosis of anemia of prematurity were considered for inclusion. Major outcome parameters included hematocrit, corrected reticulocyte count and red cell transfusion requirements. RESULTS: A total of 60 infants were enrolled (n=30 per group). Infants randomized to rHuEpo had a significantly higher post-treatment hematocrit and corrected reticulocyte count than infants in the iron only group (p<0.001). There was a trend towards fewer red cell requirements in the rHuEpo group. CONCLUSIONS: The rHuEpo regimen studied here was associated with an acute improvement in hematocrit and corrected reticulocyte counts. This study did not demonstrate a statistically significant decrease in transfusion therapy, in part related to increased subsequent use of rHuEpo in the control group. Taken together, these data demonstrate that this regimen can effectively treat anemia in convalescent premature infants. 相似文献
9.
Internal Hernias: Clinical Findings,Management, and Outcomes in 49 Nonbariatric Cases 总被引:1,自引:0,他引:1
Saber Ghiassi Scott Q. Nguyen Celia M. Divino John C. Byrn Avraham Schlager 《Journal of gastrointestinal surgery》2007,11(3):291-295
Internal hernia, the protrusion of a viscus through a peritoneal or mesenteric aperture, is a rare cause of small bowel obstruction.
We report the clinical presentation, surgical management, and outcomes of one of the largest series of nonbariatric internal
hernias. Ten-year retrospective review of patients at our institution yielded 49 cases of internal hernias. Majority of patients
presented with symptoms of acute (75%) or intermittent (22%) small bowel obstruction. While 16% of CT scans were suspicious
for internal hernia, in no cases the preoperative diagnosis of internal hernia was made. The most frequent internal hernias
were transmesenteric (57.0%) and 34 hernias (69%) were caused by previous surgery. All internal hernias were reduced and the
defects were repaired. Compromised bowel was present in 22 cases and 11 patients underwent small bowel resection. The mean
postoperative hospitalization was 10.9 days. The overall mortality rate from our series is 2%, and the morbidity rate is 12%.
Transmesenteric hernias, as complications of previous surgeries, are the most prevalent internal hernias. Preoperative diagnosis
of internal hernia is extremely difficult because of the nonspecific clinical presentation. However, if discovered promptly,
internal hernias can be repaired with acceptable morbidity and mortality.
Poster presentation at Digestive Disease Week, May 22, 2006, Los Angeles, California, USA. 相似文献
10.
Use of the deoxyuridine suppression test to evaluate localized folate deficiency in rat colonic epithelium 总被引:1,自引:0,他引:1
M L Cravo J B Mason J Selhub I H Rosenberg 《The American journal of clinical nutrition》1991,53(6):1450-1454
In this study the deoxyuridine suppression test (dUST) was performed on isolated rat colonocytes to establish its value as an indicator of folate status in the colonic epithelium. [3H]thymidine incorporation into DNA was suppressed greater than 90% by deoxyuridine (dU) concentrations greater than 2.5 mumol/L. Preincubation of cells with 5-fluorouracil (1-100 mumol/L) but not methotrexate (10-100 mumol/L) resulted in a significant decrease in the degree of suppression. The dUST performed on colonocytes from folate-deficient animals displayed less suppression than on colonocytes from folate-replete animals (P less than 0.05). The abnormal degree of suppression was corrected by adding 100 mumol folinic acid/L. There was a negative correlation between the degree of suppression and the folate concentration of the colonic epithelium (P less than 0.001). These data indicate that the dUST is useful for detecting folate deficiency in the colonic epithelium and may therefore be valuable in assessing a deficiency state localized to that epithelium. 相似文献