全文获取类型
收费全文 | 22490篇 |
免费 | 1949篇 |
国内免费 | 409篇 |
专业分类
耳鼻咽喉 | 226篇 |
儿科学 | 559篇 |
妇产科学 | 501篇 |
基础医学 | 2647篇 |
口腔科学 | 434篇 |
临床医学 | 2546篇 |
内科学 | 4184篇 |
皮肤病学 | 465篇 |
神经病学 | 1743篇 |
特种医学 | 939篇 |
外国民族医学 | 12篇 |
外科学 | 3326篇 |
综合类 | 1461篇 |
现状与发展 | 1篇 |
一般理论 | 12篇 |
预防医学 | 1637篇 |
眼科学 | 520篇 |
药学 | 1514篇 |
8篇 | |
中国医学 | 399篇 |
肿瘤学 | 1714篇 |
出版年
2024年 | 32篇 |
2023年 | 240篇 |
2022年 | 579篇 |
2021年 | 1034篇 |
2020年 | 663篇 |
2019年 | 744篇 |
2018年 | 824篇 |
2017年 | 659篇 |
2016年 | 715篇 |
2015年 | 904篇 |
2014年 | 1149篇 |
2013年 | 1234篇 |
2012年 | 1914篇 |
2011年 | 1876篇 |
2010年 | 1182篇 |
2009年 | 888篇 |
2008年 | 1370篇 |
2007年 | 1389篇 |
2006年 | 1295篇 |
2005年 | 1111篇 |
2004年 | 920篇 |
2003年 | 877篇 |
2002年 | 751篇 |
2001年 | 306篇 |
2000年 | 273篇 |
1999年 | 233篇 |
1998年 | 152篇 |
1997年 | 134篇 |
1996年 | 115篇 |
1995年 | 81篇 |
1994年 | 81篇 |
1993年 | 84篇 |
1992年 | 114篇 |
1991年 | 83篇 |
1990年 | 86篇 |
1989年 | 73篇 |
1988年 | 52篇 |
1987年 | 37篇 |
1986年 | 42篇 |
1985年 | 44篇 |
1984年 | 46篇 |
1983年 | 26篇 |
1982年 | 38篇 |
1981年 | 25篇 |
1980年 | 27篇 |
1978年 | 24篇 |
1977年 | 26篇 |
1976年 | 21篇 |
1975年 | 29篇 |
1974年 | 28篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
1.
2.
3.
Qiangsheng He Chongfei Huang Xiwen Qin Yuanyuan Yu Di Tang Junjie Huang Zi Chong Kuo Yuyao Ling Deli Mao Bin Xia Wenjing Li Kuiqing Lu Man Yang Yulong He Wenbo Meng Jinqiu Yuan Yihang Pan 《International journal of cancer. Journal international du cancer》2023,153(5):942-949
Recent epidemiological studies suggested that proton pump inhibitor (PPI) use was associated with an increased risk of biliary tract cancer (BTC), however, confounders were not adequately controlled. Our study aimed to evaluate PPI use and subsequent risk of BTC and its subtypes in three well-established cohorts. We conducted a pooled analysis of the subjects free of cancers in UK Biobank (n = 463 643), Nurses' Health Study (NHS, n = 80 235) and NHS II (n = 95 869). Propensity score weighted Cox models were used to estimate marginal HRs of PPIs use on BTC risk, accounting for potential confounders. We documented 284 BTC cases in UK Biobank (median follow-up: 7.6 years), and 91 cases in NHS and NHS II cohorts (median follow-up: 15.8 years). In UK biobank, PPI users had a 96% higher risk of BTC compared to nonusers in crude model (HR 1.96, 95% CI 1.44-2.66), but the effect was attenuated to null after adjusting for potential confounders (HR 0.95, 95% CI 0.60-1.49). PPI use was not associated with risk of BTC in the pooled analysis of three cohorts (HR 0.93, 95% CI 0.60-1.43). We also observed no associations between PPI use with risk of intrahepatic (HR 1.00, 95% CI 0.49-2.04), extrahepatic bile duct (HR 1.09, 95% CI 0.52-2.27) and gallbladder cancers (HR 0.66, 95% CI 0.26-1.66) in UK Biobank. In summary, regular use of PPIs was not associated with the risk of BTC and its subtypes. 相似文献
4.
Brittney H. Cotta Margaret F. Meagher Aaron Bradshaw Stephen T. Ryan Gerant Rivera-Sanfeliz 《Expert review of anticancer therapy》2019,19(4):301-308
Introduction: Percutaneous renal mass biopsy has evolved over the last decade with improvements on previous pitfalls including low tissue yield, high non-diagnostic rates, and complications. As understanding of tumor biology and natural history of renal cortical neoplasms has improved, percutaneous renal mass biopsy is poised to have an expanding role in an area characterized by individualized management and refined risk stratification.
Areas covered: This review summarizes the evolution of renal mass biopsy to its current state with respect to outcomes, indications, and clinical guidelines.
Expert opinion: With improved understanding of differential biological potential of renal cortical neoplasms combined with technical improvements in diagnostic yield and accuracy, utilization of renal mass biopsy is becoming an important adjunct to patient care in a broad range of clinical scenarios, including active surveillance, thermal ablation, and use of primary systemic therapy in localized and advanced settings. 相似文献
5.
6.
7.
Norwani Basir Pemasari Upali Telisinghe Vui Heng Chong 《The Indian journal of surgery》2015,77(6):545-546
Paraneoplastic pemphigus is a relatively rare but significant acquired autoimmune mucocutaneous disorder that is characterised by diffuse erythema, painful blistering and sores of the skin and mucus membranes. The underlying pathogenesis is believed to be triggered by altered immune system in response to underlying neoplasm. The manifestations can predate, occur at the same time or after the diagnosis of cancer. Associations with gastric cancer have only been reported twice. A 78-year-old lady presented with a month’s history of extensive skin lesions that started off as bullous lesions and biopsy revealed bullous pemphigus. Endoscopy for anemia revealed gastric cancer. This case reinforced the need to consider underlying malignancy in elderly patient with new onset dermatological presentation. 相似文献
8.
Aaron Pitzele Mohammad Rahimi Eric Armbrecht 《The journal of maternal-fetal & neonatal medicine》2015,28(15):1770-1773
Objective: To determine whether packed red blood cell (PRBC) transfusion affects post-prandial superior mesenteric artery blood flow velocities (SMA BFVs) in very-low birth weight (VLBW) neonates and if so, at what time point after transfusion restoration of previous SMA BFV patterns occurs.Design/Methods: VLBW pre-term neonates, older than 14 days and tolerating bolus enteral feedings administered every 3?h were enrolled in this prospective observational study. Pulsed Doppler ultrasound was used to measure pre- and post-prandial (at 45?min) time-averaged mean, peak and end diastolic velocities (TAMV, PSV, EDV) immediately before and after 15?ml/kg of PRBC transfusion was given over 3?h; patent ductus arteriosus (PDA) status was also evaluated. Subsequent pre- and post-prandial SMA BFVs were recorded 24 and 48?h after the transfusion.Results: Pre- and post-prandial measurements were obtained for 21 out of 25 enrolled infants. Post-prandial SMA BFVs were attenuated during the feedings immediately after transfusion; at 24 and 48?h after transfusion, changes in post-prandial SMA BFVs were similar to those measured prior to transfusion; the presence of the PDA did not affect results.Conclusions: PRBC transfusion blunted SMA BFV responses to feedings immediately after the transfusion with normalization observed 24?h post-transfusion. 相似文献
9.