血清CA125测定在妇科疾病中的应用价值

探讨血清ＣＡ１２５抗原测定对卵巢上皮癌等妇科疾病的临床应用价值。方法采用放射免疫法测定２０５例妇科疾病治疗前后血清ＣＡ１２５抗原含量。结果以ＣＡ１２５＞３５Ｕ／ｍｌ为阳性，其阳性率在卵巢上皮癌及子宫腺肌症或子宫内膜异位症分别为８４．６％（１１／１３）和６４％（１６／２５）。１１例血清ＣＡ１２５阳性的卵巢上皮癌患者经有效化疗和手术后，有９例＜３５Ｕ／ｍｌ以下。１６例ＣＡ１２５阳性的子宫腺肌症及子宫内膜异位症患者术后６周后均＜３５Ｕ／ｍｌ。当ＣＡ１２５复升高，预示上述疾病复发。结论血清ＣＡ１２５测定对卵巢上皮癌、子宫肌腺症和子宫内膜异位症的诊断、疗效评价和复发预测具有重要意义。     

侧脑室注射微量五肽胃泌素对大鼠胃电和胃运动的影响

在大鼠侧脑室微量注入五肽胃泌素(G-5)0.1μg观察其对胃电和胃运动的影响。实验结果表明:侧脑室注射G-5(0.1μg/10μl)后胃电慢波的振幅由对照值的0.56mV增加到0.847mV(P<0.01),快波的振幅和频率也明显增加;胃窦运动频率增加到对照值的41.556±1.01%(P<0.01),振幅增加196.68±2.07%(P<0.001)。这一反应被切断双侧颈迷走神经所阻断。提示脑内的胃泌素可参与对胃电和胃运动的调节,这一作用可能是通过迷走神经来实现的。     

827例开放性骨折创面的细菌学调查

感染是开放性骨折的严重并发症之一。开放性骨折术后感染与创面污染的细菌种类密切相关[1～ 3 ] 。本文对我科收治的 82 7例开放性骨折创面 3～4次不同时间采集标本进行细菌种类检测 ,以明确开放性骨折创面的细菌种类及来源 ,探讨开放性骨折创面细菌污染的相关因素 ,为治疗提供依据。材料与方法　我科于 1 997年 9月至 2 0 0 2年 7月间收治的 82 7例开放性骨折病例。男 671例 ,女1 5 6例。年龄 3～ 79岁 ,平均 3 7岁。术后创口感染 1 3例。创面采集标本第 1次在接诊室 ,第 2次在手术室清创术前 ,第 3次在清创术后创口闭合前 ,第 4次在术后创…     

INTRA-ARTERIAL CISPLATIN CHEMOTHERAPY WITH SURGERY AND/OR RADIOTHERAPY IN ADVANCED CERVICAL AND VAGINAL CARCINOMA

Seventy-four advanced cases of cervical (72) and vaginal (2) carcinoma were admitted consecutively since October 1980. A follow-up study of the thera- peutic results of intraarterial (lA) cisplatin infusions iri combination with surgery and/or radiotherapy was made up to August 1984. The clinical anatomic stage was found to be the most significant factor in influencing the outcome of prognosis. ' The lA cisplatin treatment achieved a high response rate (83.8%) which converted 36 (48.6%) of the 74 non resectable cases into resectable ones. The medial survival period for the 9 far-advanced cases who re ceived IA cisplatin treatment alone was 9.5 months. The over-all relapse-free remission rate and survival rate of the 74 were 62.9% + 7.79% and 74.41% + 3.49%. The patients treated by the lA cisplatin, surgery and radiotherapy fared best and this com- bination is the treatment of choice in advanced cer vical and vaginal carcinoma.