经闭孔无张力尿道中段悬吊术治疗女性压力性尿失禁的临床观察

Objective To evaluate the efficacy and safety of the transobturator tension-free vaginal tape (TVT-O) surgery, a minimally invasive surgery for treating patients with the stress urinary incontinence (SUI). Methods 28 cases with female stress uri-nary incontinence treated by TVT-O procedure from April 2006 to June 2008 were retrospectively analyzed. The follow-up time is from 4 to 24 months. Results The mean operation time was 23 min (rang 10～30 min) and the mean intraoperative bleeding was 24 ml (range 15～40 ml). An indwelling catheter had been used for 3 d because of urinary retention in 3 cases. 24 patients(85.7%)reached complete control after the surgery,effective control in 4 patients(14.35%). Conclusions TVT-O surgery is an effective, safe, minimally invasive management to treat the stress urinary incontinence.     

屈螺酮和炔雌醇复合片治疗绝经过渡期异常子宫出血的临床观察

目的探讨屈螺酮和炔雌醇复合片（商品名：优思明）对绝经过渡期异常子宫出血的疗效。方法对2009年4～9月来中山市博爱医院妇科门诊就诊的绝经过渡期异常子宫出血患者50例,采用屈螺酮3mg和炔雌醇30μg复合片周期治疗,即月经第1天开始口服,1片/d,21d/周期,停7d,再进行下一个周期,共6个周期。观察用药后1、3、6个月的疗效。结果 50例患者用药后,月经量明显减少,合并贫血者血红蛋白升高,体重和血压较用药前均有所下降。结论屈螺酮和炔雌醇复合片对绝经过渡期异常子宫出血有肯定的疗效。     

经闭孔无张力尿道中段悬吊术治疗女性压力性尿失禁的临床观察

Objective To evaluate the efficacy and safety of the transobturator tension-free vaginal tape (TVT-O) surgery, a minimally invasive surgery for treating patients with the stress urinary incontinence (SUI). Methods 28 cases with female stress uri-nary incontinence treated by TVT-O procedure from April 2006 to June 2008 were retrospectively analyzed. The follow-up time is from 4 to 24 months. Results The mean operation time was 23 min (rang 10～30 min) and the mean intraoperative bleeding was 24 ml (range 15～40 ml). An indwelling catheter had been used for 3 d because of urinary retention in 3 cases. 24 patients(85.7%)reached complete control after the surgery,effective control in 4 patients(14.35%). Conclusions TVT-O surgery is an effective, safe, minimally invasive management to treat the stress urinary incontinence.     

铂类和氟化嘧啶类药物对宫颈癌移植瘤抑制作用的实验研究

目的 研究铂类和氟化嘧啶类药对HeLa细胞裸鼠移植瘤的抑制作用.方法 将HeLa细胞注射于4～6周龄的雌性裸小鼠皮下,药物分组如下：A为对照组、B1为顺铂组、B2为卡铂组、B3为5-Fu组、B4为卡培他滨组、B5为顺铂＋5-Fu组、B6为顺铂＋卡培他滨组、B7为卡铂＋5-Fu组.结果 肿瘤体积变化：各实验组都能抑制肿瘤生长,与对照组比较,有显著性差异,P＜0.05.B1、B2、B3、B4、B5、B6、B7的抑瘤率分别是：47.59%、56.83%、27.36%、34.63%、72.64%、80.00%、59.10%.用药后B1、B2、B5、B6、B7的肿瘤质量明显小于对照组,有显著性差异,P＜0.05,其中B5、B6的瘤量明显轻于B3的,P＜0.05,但是析因分析结果得出无正交互效应.结论 关于宫颈癌移植瘤的化疗,卡铂可以替代顺铂;卡培他滨为口服制剂,使用方便,可以替代5-Fu;联合用药时各药物之间的抗肿瘤作用并没有相互增强而只是药效的相加.     

宫颈癌前病变患者电子档案的建立与信息化管理模式的探讨*

目的探讨宫颈癌前病变患者电子档案的建立与信息化管理模式,提高宫颈癌前病变患者的随访率,及早发现宫颈癌,降低死亡率。方法成立宫颈病变中心,由专职医护人员建立宫颈癌前病变患者电子档案,所有信息及时录入中山市妇幼信息系统,对患者进行及时随访。结果宫颈癌共筛查130 475人,TCT异常5 559人,TCT阳性率为4.26%。复诊人数3 337人,复诊率为60.03%。共检出宫颈癌前病变972例,其中CIN I 411例,CIN II 267例,CIN III 294例。对中山市宫颈癌前病变患者进行系统管理,TCT筛查阳性随访率由2011年的63.50%上升至2015年的80.58%。宫颈癌前病变患者随访率由实施前的19.05%上升至实施后的76.19%。结论宫颈癌前病变患者电子档案的建立及信息化管理,可以加强患者的随访管理,提高随访率,保证患者就诊资料及时性、完整性和连续性,全市妇幼机构医护人员可以随时查看患者就诊情况,提高工作效率,方便科研人员统计分析,及时发现问题并解决。     

自然妊娠发生输卵管双胎妊娠1例

患者40岁,因"停经57天"入院。既往史:顺产2次,人流1次,平素月经规则,末次月经2013-10-08。本次妊娠前未服用任何药物,停经后无恶心、呕吐等妊娠反应,无下腹痛,无阴道流血等不适。2013-12-04患者至我院行阴道彩超检查,结果显示:子宫内膜厚14 mm,子宫内未见明显孕囊回声,左侧附件区左侧卵巢旁见37 mm×25 mm混合回声包块,包块内见一无     

正常晚期妊娠孕妇脑钠肽参考值的研究

目的:探讨正常妊娠晚期孕妇氨基末端脑钠肽(NT-proBNP)水平并确立其正常值范围,为临床应用提供参考。方法:用电化学发光免疫方法测定1 860名正常晚期妊娠孕妇血清脑钠肽NT-proBNP水平。结果:正常晚期妊娠孕妇血清NT-proBNP水平为(56.93±42.04)pg/ml(5~364.90 pg/ml)。并进一步将1 860例正常晚期妊娠孕妇分为3个亚组,即A组(孕28~31周)、B组(32~34周)、C组(≥孕35周),其值分别为(51.99±43.45)pg/ml、(58.87±52.91)pg/ml、(55.11±51.65)pg/ml,差异无统计学意义。结论:该文在国内首次用电化学发光免疫法测得中国正常晚期妊娠孕妇脑钠肽(NT-proBNP)水平,样本量大,其结果可以初步确立正常晚期妊娠孕妇脑钠肽参考值的范围。     

经闭孔无张力尿道中段悬吊术治疗女性压力性尿失禁的临床观察

Objective To evaluate the efficacy and safety of the transobturator tension-free vaginal tape (TVT-O) surgery, a minimally invasive surgery for treating patients with the stress urinary incontinence (SUI). Methods 28 cases with female stress uri-nary incontinence treated by TVT-O procedure from April 2006 to June 2008 were retrospectively analyzed. The follow-up time is from 4 to 24 months. Results The mean operation time was 23 min (rang 10～30 min) and the mean intraoperative bleeding was 24 ml (range 15～40 ml). An indwelling catheter had been used for 3 d because of urinary retention in 3 cases. 24 patients(85.7%)reached complete control after the surgery,effective control in 4 patients(14.35%). Conclusions TVT-O surgery is an effective, safe, minimally invasive management to treat the stress urinary incontinence.     

经闭孔无张力尿道中段悬吊术治疗女性压力性尿失禁的临床观察

Objective To evaluate the efficacy and safety of the transobturator tension-free vaginal tape (TVT-O) surgery, a minimally invasive surgery for treating patients with the stress urinary incontinence (SUI). Methods 28 cases with female stress uri-nary incontinence treated by TVT-O procedure from April 2006 to June 2008 were retrospectively analyzed. The follow-up time is from 4 to 24 months. Results The mean operation time was 23 min (rang 10～30 min) and the mean intraoperative bleeding was 24 ml (range 15～40 ml). An indwelling catheter had been used for 3 d because of urinary retention in 3 cases. 24 patients(85.7%)reached complete control after the surgery,effective control in 4 patients(14.35%). Conclusions TVT-O surgery is an effective, safe, minimally invasive management to treat the stress urinary incontinence.